Electron scattering and transport for plasma-liquid interactions. The project aims to address the emerging technologies associated with the interaction of plasmas with liquids and biological matter, including plasma medicine. The project expects to generate new knowledge on the role of electron-induced processes through the development of complete and accurate sets of microscopic cross-sections for electrons with biomolecules within tissue. This microscopic data will inform new microscopic model ....Electron scattering and transport for plasma-liquid interactions. The project aims to address the emerging technologies associated with the interaction of plasmas with liquids and biological matter, including plasma medicine. The project expects to generate new knowledge on the role of electron-induced processes through the development of complete and accurate sets of microscopic cross-sections for electrons with biomolecules within tissue. This microscopic data will inform new microscopic models for non-equilibrium electron transport in liquids and biological matter, and its coupling to plasmas. The expected outcomes of this project include progress towards the optimisation of safety/efficacy of future generation plasma medicine devices through detailed understanding of plasma-biological tissue interactions.Read moreRead less
Low-energy electron transport in soft-condensed biological matter. To obtain optimal accuracy and selectivity of ionising radiation based technologies requires an understanding and quantification of the underpinning fundamental physical processes. This project will focus on developing accurate theoretical models of low-energy electron transport in biological matter which account for new physical mechanisms.
Cellular Cross-talk Between Liver Progenitor Cells And Hepatic Stellate Cells Is Required For Hepatic Fibrogenesis
Funder
National Health and Medical Research Council
Funding Amount
$618,517.00
Summary
Deloitte Access Economics data proposes the total economic burden of liver disease in Australia in 2012 was >$50 billion. This study will identify how the liver heals itself by inducing liver cell populations which interact to regenerate damaged liver tissue in chronic liver disease. This knowledge may lead to the development of novel therapeutic interventions for the treatment of liver scarring and liver cancer, and to assist in normal liver regeneration following chronic liver disease.
Novel collision experiments with metastable neon atoms in an atom trap. The aim of this project is to investigate collisions involving atoms in long lived excited states (metastable states). The project will utilise a magneto-optical trap to investigate electron-atom collisions as well as interatomic collisions for ultra-cold atoms. The outcomes of such investigations extend scientific knowledge of these important processes as a well as provide data for testing fundamental scattering theories. T ....Novel collision experiments with metastable neon atoms in an atom trap. The aim of this project is to investigate collisions involving atoms in long lived excited states (metastable states). The project will utilise a magneto-optical trap to investigate electron-atom collisions as well as interatomic collisions for ultra-cold atoms. The outcomes of such investigations extend scientific knowledge of these important processes as a well as provide data for testing fundamental scattering theories. This scientific knowledge may lead to further technological advances such as more efficient light sources or a metastable-atom laser that could be used for the production of nano-scale electric circuits.Read moreRead less
Role Of Hepatic Stellate Cell And Liver Progenitor Cell Interactions In The Regulation Of Wound Healing And Liver Regeneration
Funder
National Health and Medical Research Council
Funding Amount
$620,716.00
Summary
The liver has a remarkable capacity for regeneration following acute and chronic liver injury, however, the mechanisms which facilitate this wound healing are not understood. This project will examine the interactions between different liver cell populations, including hepatic stellate cells (liver fibroblasts) and liver progenitor cells (stem cells of the liver) and will determine which factors regulate inflammation, liver scarring and restitution of liver mass following chronic liver injury.
A Photonic Interconnect for Trapped Ion Quantum Computing. Computer networks are the foundation of our digital economy. Quantum computing offer revolutionary solutions to current limitations by taking advantage of quantum physics. Methods for factoring large numbers or searching unordered databases run with significantly fewer operations on quantum computers. Quantum encryption offers completely secure communication. There have been small-scale demonstrations of these technologies, and clear roa ....A Photonic Interconnect for Trapped Ion Quantum Computing. Computer networks are the foundation of our digital economy. Quantum computing offer revolutionary solutions to current limitations by taking advantage of quantum physics. Methods for factoring large numbers or searching unordered databases run with significantly fewer operations on quantum computers. Quantum encryption offers completely secure communication. There have been small-scale demonstrations of these technologies, and clear roadmaps exist for large-scale implementations. We will advance the state of the art by interconnecting light based quantum communication and trapped ion quantum computing together with phase Fresnel lenses, a micro-fabricated optic similar to a computer generated holographic plate.Read moreRead less
Attosecond physics with ultra cold metastable neon. This research will generate new knowledge about how atoms behave when they are placed in strong optical fields. One of the phenomena which can be observed in these systems is the production of extreme ultraviolet radiation. This radiation has potential applications in areas as diverse as precision spectroscopy and structural biology. The research will use the recently ARC funded, state-of-the-art short pulse laser facility, ultra-cold atom trap ....Attosecond physics with ultra cold metastable neon. This research will generate new knowledge about how atoms behave when they are placed in strong optical fields. One of the phenomena which can be observed in these systems is the production of extreme ultraviolet radiation. This radiation has potential applications in areas as diverse as precision spectroscopy and structural biology. The research will use the recently ARC funded, state-of-the-art short pulse laser facility, ultra-cold atom trap technology and will provide excellent research training opportunities for higher degree students. The outcomes of the research project will enable Australian researchers to make significant contributions to the exciting field of attosecond science which is still in its infancy.
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Mechanisms Of Hepatic Fibrogenesis In Chronic Liver Disease
Funder
National Health and Medical Research Council
Funding Amount
$697,209.00
Summary
Despite advances made in understanding the mechanisms of liver injury, chronic liver disease continues to be one of the most rapidly growing causes of death in subjects aged <65 years. This is the result of uncontrolled wound healing and regeneration leading ultimately to cirrhosis and liver cancer. This research will identify and characterise pathways that control the wound healing response to liver injury, involving the processes of inflammation, scarring and restitution of normal liver mas ....Despite advances made in understanding the mechanisms of liver injury, chronic liver disease continues to be one of the most rapidly growing causes of death in subjects aged <65 years. This is the result of uncontrolled wound healing and regeneration leading ultimately to cirrhosis and liver cancer. This research will identify and characterise pathways that control the wound healing response to liver injury, involving the processes of inflammation, scarring and restitution of normal liver mass.Read moreRead less