Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453480
Funder
Australian Research Council
Funding Amount
$236,899.00
Summary
Nanostructured Polymer Processing Network. The Nanostructured Polymer Processing Network will promote the understanding and manipulation of the processing of novel nanostructured plastic materials. High technology, online polymer processing equipment will be sought that will enable the design of nanostructured polymers via a range of techniques including insitu polymerisation, nanocomposites and polymer blending which are ideal for designing high value nanostructured polymers that are tailored f ....Nanostructured Polymer Processing Network. The Nanostructured Polymer Processing Network will promote the understanding and manipulation of the processing of novel nanostructured plastic materials. High technology, online polymer processing equipment will be sought that will enable the design of nanostructured polymers via a range of techniques including insitu polymerisation, nanocomposites and polymer blending which are ideal for designing high value nanostructured polymers that are tailored for high performance applications. The equipment in this proposal, when combined with existing leading edge polymer characterisation and analysis equipment, will provide a Network with international state-of-the-art equipment that will fast track the success of integrated research projects across the sites.Read moreRead less
Safety And Efficacy Of A Surgically Implanted Suprachoroidal Retinal Prosthesis (Bionic Eye)
Funder
National Health and Medical Research Council
Funding Amount
$1,233,826.00
Summary
A bionic eye is a electronic device which can stimulate the remaining visual pathway in a person who is blind, to restore some basic vision. Our team have previously shown that our novel bionic eye device can be safely implanted in a patient, and can give improvements in vision when tested in a laboratory environment. The next stage of the research is to provide patients with a more advanced device, which will contain more electrodes and also be able to be taken home.
A Systematic Evaluation Of The Neurosurgical Application Of Peri-operative And Intra-operative MR Tractography In Different Paediatric Disease States
Funder
National Health and Medical Research Council
Funding Amount
$130,910.00
Summary
My research investigates changes in brain nerve fibre tracts/white matter in paediatric disease states and changes related to surgery by using nerve fibre tract imaging before, during and after surgery. It will also generate an imaging atlas to help understand white matter pathway development. It then serves as normative comparison to better understand aberrations in diseased neural pathways. The outcome will aid understanding in brain development, recovery and plasticity, and helps improve whit ....My research investigates changes in brain nerve fibre tracts/white matter in paediatric disease states and changes related to surgery by using nerve fibre tract imaging before, during and after surgery. It will also generate an imaging atlas to help understand white matter pathway development. It then serves as normative comparison to better understand aberrations in diseased neural pathways. The outcome will aid understanding in brain development, recovery and plasticity, and helps improve white matter lesion localisation.Read moreRead less
Improving The Long-term Outcomes Of The Australian And New Zealand Fontan Population
Funder
National Health and Medical Research Council
Funding Amount
$89,836.00
Summary
The Fontan procedure is the last of a series of operations offered to children born with hearts with a single pumping chamber. Without this procedure these children would die, however, with this procedure their long-term expectations are still uncertain. This study will investigate the long-term outcomes of the Australian and New Zealand Fontan population and how these outcomes can be improved.
Reduction Of Chronic Post-surgical Pain With Ketamine - ROCKet Study
Funder
National Health and Medical Research Council
Funding Amount
$4,823,395.00
Summary
Chronic post-surgical pain (CPSP) is a common complication of major surgery, and a significant burden on quality of life and ongoing health costs. Ketamine is a drug used by anaesthetists to treat severe acute surgical pain. Various small studies suggest that it may be unique in its ability to reduce the risk of CPSP. We propose a large trial of ketamine during & after anaesthesia for major surgery to test this. Demonstration of effectiveness would promote widespread change in clinical practice.
Regulation Of Key Pathways Causing Peri-implant Bone Loss.
Funder
National Health and Medical Research Council
Funding Amount
$403,639.00
Summary
The failure of bone prostheses is becoming a major health problem in our aging population. Despite the impressive success of joint replacement surgery, a significant number of arthroplasties fail. It is now apparent that most implants fail due to bone loss around them which leads to loosening. This project aims to obtain a better understanding of the causes of implant failure and find ways to extend the life of these implants .
Clinical Trial Of A Suprachoroidal Visual Prosthesis For The Profoundly Vision Impaired
Funder
National Health and Medical Research Council
Funding Amount
$1,098,802.00
Summary
For 15 years we have been designing a bionic eye. We have made a device called the Phoenix99 and shown in short term animal tests that it is both safe to implant but also that it potentially performs better than any other device in the world. We are requesting funds to complete longer term animal testing of the device and then commence a small human clinical trial to demonstrate the benefits of the technology – specifically that it is able to help blind people navigate without assistance.
New Biomimetic Nanostructured Coatings for Hip Implants. Over 30,000 hip implants operations take place in Australia each year, due largely to a significant and growing proportion of the population suffering from conditions such as osteoporosis. The coating on the implants, required to cause good bone ingrowth and adhesion between bone and implant, is far from perfect. We propose to spray coatings which mimic the structure of bone, and thus offer improved mechanical properties such as appropriat ....New Biomimetic Nanostructured Coatings for Hip Implants. Over 30,000 hip implants operations take place in Australia each year, due largely to a significant and growing proportion of the population suffering from conditions such as osteoporosis. The coating on the implants, required to cause good bone ingrowth and adhesion between bone and implant, is far from perfect. We propose to spray coatings which mimic the structure of bone, and thus offer improved mechanical properties such as appropriate rigidity and toughness, and stimulate better bone growth at the interface. In this way the implant should be much longer lasting and the need for undesirable revision surgery reduced. The processing technique proposed could also be a useful platform coating technology in a number of other industries.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560981
Funder
Australian Research Council
Funding Amount
$160,940.00
Summary
Confronting the Challenges in Modern Spectroscopy of Polymers. Polymers and nanocomposites are increasingly being used in new, high value applications as diverse as medicine, structural engineering, optics and electronics. In order to control and understand polymer performance, a detailed knowledge of the chemical structure at all stages in their lifecycle is required - in the liquid, rubber and solid states and during degradation. This application seeks to establish a coordinated Polymer Spectr ....Confronting the Challenges in Modern Spectroscopy of Polymers. Polymers and nanocomposites are increasingly being used in new, high value applications as diverse as medicine, structural engineering, optics and electronics. In order to control and understand polymer performance, a detailed knowledge of the chemical structure at all stages in their lifecycle is required - in the liquid, rubber and solid states and during degradation. This application seeks to establish a coordinated Polymer Spectroscopy Network using new forms of infrared and NMR spectroscopy to probe samples (usually of an non-planar geometry) in a range of configurations. These will be used simultaneously with other techniques such as rheology or thermogravimetry, and will produce capabilities unique in Australia.Read moreRead less
Modelling for Optimisation and Scale-up of the Multilayer Blown Film Process. Multilayered blown film plastic films play an important role in the food and packaging industry in Australia and SE Asia. This project aims to predict the polymer film properties for a large scale line based on experimental data from the pilot scale studies using limited quantities of polymer. This project will investigate the fundamental rheology of polymer resins and blends used for multilayered films and correlate ....Modelling for Optimisation and Scale-up of the Multilayer Blown Film Process. Multilayered blown film plastic films play an important role in the food and packaging industry in Australia and SE Asia. This project aims to predict the polymer film properties for a large scale line based on experimental data from the pilot scale studies using limited quantities of polymer. This project will investigate the fundamental rheology of polymer resins and blends used for multilayered films and correlate these to the operating parameters in pilot and industrial scales using blown-film models. The interrelationship between the models in two scales will result in reducing trial and error and will optimise production costs.Read moreRead less