Investigating Biomarkers Of Dementia And Improving Clinical Criteria Using Population- And Clinic-based Approaches
Funder
National Health and Medical Research Council
Funding Amount
$264,704.00
Summary
It is difficult to accurately diagnose an individual with dementia especially at early stages of the disease. This project aims to see what markers in the brain differentiate those with and without subtypes of dementia and to see what clinical criteria best relate to these markers. It is hoped that results will improve clinical criteria for dementia and its subtypes, thus improving the diagnostic accuracy of dementia.
Maternal And Neonatal Vaccination - How Early Can We Protect Infants?
Funder
National Health and Medical Research Council
Funding Amount
$196,331.00
Summary
Currently, only hepatitis B vaccine is routinely given at birth and for all other vaccines the earliest recommended administration is at 6 weeks old. This is too late to protect infants against pertussis and the most severe cases (hospitalisation or death) occur before 4 months. This research aims to assess if birth pertussis vaccination can protect infants earlier, measure the longevity of immunity following birth hepatitis B vaccination and examine the potential role for maternal vaccination
Modelling The Evolution Of Hepatitis C Virus By Integrating Large Sequence- And Immunological-databases.
Funder
National Health and Medical Research Council
Funding Amount
$289,980.00
Summary
Two hundred million people are infected with the Hepatitis C virus. There is no vaccine and the rate at which new strains of the virus arise enable it to evade the human immune system. This study aims to decipher how new viral strains are generated and transmitted, thereby enabling the development of new vaccines.
A Practical New Method Of Measuring Population Salt Intake
Funder
National Health and Medical Research Council
Funding Amount
$327,193.00
Summary
The World Health Organization has set a target for member countries to reduce salt intake by 30% by 2025. Key to this is measurement of population salt intake. Collection of 24-hour urine samples is the gold standard used to estimate salt intake but this method is burdensome. Collection of a single urine sample is an alternative method. This project will bring together all of the available data worldwide to assess the reliability of using a single urine sample to measure population salt intake.
Stroke Outcomes Following Catheter Ablation In Patients With Atrial Fibrillation
Funder
National Health and Medical Research Council
Funding Amount
$408,353.00
Summary
Atrial fibrillation is the most common heart rhythm disorder encountered in clinical practice. It is an irregular rhythm that predisposes individuals to stroke. Recently, catheter ablation has been shown to be successful in controlling this irregular rhythm. My research will investigate whether this treatment will decrease the risk of stroke in patients with atrial fibrillation by following a large cohort of patients after catheter ablation compared to those who have not underwent the procedure.
The first kernels of cardiovascular disease begin very early in life; in the womb and early infancy. These early indications are known to track into adulthood, eventually resulting in diseases such as heart attacks. Dr Huang has found that childhood obesity, high blood pressure, cholesterol and a "prediabetes" profile, cluster together and additionally are associated with many factors in the womb and first few years of life. She investigates how to give babies the optimal healthy start.