Elucidating the molecular mechanisms underlying migraine and endometriosis via genetic dissection. The research aims to identify genetic variants underlying migraine and endometriosis susceptibility. Advances in the genetics of these common and painful disorders, including identification of genetic biomarkers (genetic variations that can predict disease susceptibility, disease outcome, or treatment response), will offer better rationales for scientific enquiry, helping the discovery of new treat ....Elucidating the molecular mechanisms underlying migraine and endometriosis via genetic dissection. The research aims to identify genetic variants underlying migraine and endometriosis susceptibility. Advances in the genetics of these common and painful disorders, including identification of genetic biomarkers (genetic variations that can predict disease susceptibility, disease outcome, or treatment response), will offer better rationales for scientific enquiry, helping the discovery of new treatment pathways and improve predictions of drug efficacy and safety. Thus providing improved treatment strategies for the individual sufferer and reduce the direct medical and indirect economic costs to individual sufferers as well as to the general community.Read moreRead less
Novel Epidemiological Methods To Infer The Causal Effects Of Risk Factors On Neuropsychiatric And Cardiovascular Disorders
Funder
National Health and Medical Research Council
Funding Amount
$182,003.00
Summary
Epidemiological studies, which associate risk factors and disease, are central in informing public health policy. Because causality is difficult to ascertain from these associations, public health interventions based on these findings are at some risk of failure. We propose to develop, extend and apply an innovative epidemiological approach, Mendelian randomization (MR) to resolve the causal relationship between risk factors and neuropsychiatric and cardiovascular disorders.
Humanitarian migrants' settlement in Australia: A longitudinal study. Current evidence suggests that humanitarian migrants settle less successfully than other immigrants both economically and socially. This project aims to examine the causal mechanisms and pathways to economic, sociocultural and political settlement outcomes of humanitarian migrants to Australia. This project expects to generate new knowledge in the area of humanitarian migrants’ settlement by using nationally representative dat ....Humanitarian migrants' settlement in Australia: A longitudinal study. Current evidence suggests that humanitarian migrants settle less successfully than other immigrants both economically and socially. This project aims to examine the causal mechanisms and pathways to economic, sociocultural and political settlement outcomes of humanitarian migrants to Australia. This project expects to generate new knowledge in the area of humanitarian migrants’ settlement by using nationally representative data and cutting-edge longitudinal techniques.Expected outcomes include enhanced research capacity in causal methods, interdisciplinary and institutional collaborations, and evidence-based social policy for humanitarian migrants, significantly benefitting humanitarian migrants directly and society more broadly. Read moreRead less
From science to policy: quantifying and managing the risk of mosquito borne disease in the context of climate change. It is important to assess and manage the health risks of climate change. This research will create fundamental knowledge and practical skills on the interdisciplinary assessment and management of health risks of climate change, and explore policy ramifications of research outcomes in this study.
Trajectories and turning points for women's reproductive health. This project will take a whole life perspective to investigate women’s reproductive health. It uses data from more than 150,000 women in 10 cohort studies across six nations. Findings will advance our understanding of reproductive health and will support a more tailored approach to women’s health policy and strategies for healthy ageing.