The Effect Of Aging And Mitochondria Dysfunction On Optic Nerve Response To Oxidative Stress In Glaucoma
Funder
National Health and Medical Research Council
Funding Amount
$100,381.00
Summary
Glaucoma is a disease of the nerve cells in the retina and optic nerve of the eye, it is the second most common cause of blindness worldwide. The risk of developing glaucoma increases exponentially with age but the mechanisms that predispose older individuals to glaucoma are not known. This study examines whether age-related changes in mitochondria, a characteristic finding in aging, results in increase susceptibility to glaucoma development.
OCULAR PERFUSION PRESSURE: A MODIFIABLE RISK FACTOR FOR GLAUCOMA?
Funder
National Health and Medical Research Council
Funding Amount
$327,560.00
Summary
This project aims to study the mechanisms underlying glaucoma, the second leading cause of vision loss. Specifically it will provide proof for the idea that a person can develop vision loss without having high eye pressure, if their blood pressure cannot provide enough supply to the eye. It will achieve this by combining expertise from several disciplines; physiology, blood pressure control, anatomy and biochemistry. This project will help to improve glaucoma detection, monitoring and treatment.