Evaluation Of The Incorporation Of WHO Guidelines Into Post-graduate Medical Curriculum; The Impact On Quality Of Care
Funder
National Health and Medical Research Council
Funding Amount
$130,704.00
Summary
There is abundant evidence that many patients do not receive medical treatments of proven effectiveness. This is even more apparent in developing countries. Strategies to improve use of proven treatments is needed. Our research aims to evaluate an educational program for doctors in Lao PDR, based on World Health Organisation guidelines for the care of sick children in hospitals, including the impact on the knowledge of doctors and on the quality of care in the hospitals in which they work.
The Epidemiology Of Post Thrombotic Syndrome Following The Use Of Central Venous Lines In Paediatrics
Funder
National Health and Medical Research Council
Funding Amount
$130,203.00
Summary
The association between central venous lines (CVL) and blood clots in children is well known. Possible consequences of CVL-related blood clots are line blockage, pulmonary embolism (blood clots in the lungs) and post-thrombotic syndrome (PTS). PTS symptoms can be physically limiting, painful and disfiguring. Yet as the incidence of PTS is unknown, the importance of treating CVL-related blood clots is unclear. This study will assess the incidence of PTS and the associated risk factors in children ....The association between central venous lines (CVL) and blood clots in children is well known. Possible consequences of CVL-related blood clots are line blockage, pulmonary embolism (blood clots in the lungs) and post-thrombotic syndrome (PTS). PTS symptoms can be physically limiting, painful and disfiguring. Yet as the incidence of PTS is unknown, the importance of treating CVL-related blood clots is unclear. This study will assess the incidence of PTS and the associated risk factors in children.Read moreRead less
Characterization Of Sex-Specific Differences In Cardiovascular Adaptation In The First Three Years Of Life
Funder
National Health and Medical Research Council
Funding Amount
$567,725.00
Summary
Male babies born significantly premature are up to twice likely to die than females. The reasons for this are unknown. This study will determine the cardiovascular differences in male and female babies born preterm and will examine how they adapt over the first 5 days. Defining the mechanisms that contribute to the difference in mortality between the sexes will also show how changes starting around birth affect the way the blood pressure system functions for life, a major lifetime stroke risk.
Immunisation Safety And Adverse Events: Improving Our Understanding Of Causes And Management
Funder
National Health and Medical Research Council
Funding Amount
$295,223.00
Summary
As the incidence of vaccine preventable diseases declines, adverse events following vaccination become increasingly important for both public and providers. This fellowship aims to improve our understanding of the risks of vaccination, potential causes, including genetic predisposition and long term clinical outcomes. A range of epidemiological, clinical and genetics studies will be performed. All these studies are targeted to understand who, what, how and why vaccine reactions occur and what ca ....As the incidence of vaccine preventable diseases declines, adverse events following vaccination become increasingly important for both public and providers. This fellowship aims to improve our understanding of the risks of vaccination, potential causes, including genetic predisposition and long term clinical outcomes. A range of epidemiological, clinical and genetics studies will be performed. All these studies are targeted to understand who, what, how and why vaccine reactions occur and what can be done to prevent or manage them better.Read moreRead less
Immunisation Practice And Policy Development In Australia: Responding To Urgent Priorities In Prevention Of Endemic And Epidemic Infectious Diseases In Children.
Funder
National Health and Medical Research Council
Funding Amount
$401,361.00
Summary
Despite high immunisation coverage rates in Australia deaths still occur in young infants from vaccine preventable diseases such as whooping cough, meningitis and influenza. My research in vaccines and immunisation involves trialing new vaccines such as meningococcal B and H1N1 vaccine to ensure their safety and effectiveness in children and investigation of new ways to deliver vaccines to improve uptake of new vaccines in the community to ensure earlier and better protection for infants and chi ....Despite high immunisation coverage rates in Australia deaths still occur in young infants from vaccine preventable diseases such as whooping cough, meningitis and influenza. My research in vaccines and immunisation involves trialing new vaccines such as meningococcal B and H1N1 vaccine to ensure their safety and effectiveness in children and investigation of new ways to deliver vaccines to improve uptake of new vaccines in the community to ensure earlier and better protection for infants and children against severe infectious diseases.Read moreRead less
Can Pentoxifylline Improve Long-term Outcomes In Preterm Infants With Late-onset Sepsis Or Necrotizing Enterocolitis – A Pragmatic, Randomized, Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,901,130.00
Summary
Very preterm infants are at high risk of death and disability. Brain injury is often the result of inflammation caused by infection or bowel disease. To date, there is no treatment to reduce the harmful effects of inflammation. Pentoxifylline reduces inflammation and is a promising, safe and inexpensive treatment option for preterm infants. This study will determine whether Pentoxifylline in addition to antibiotics improves survival without disability in preterm infants.