Geelong Osteoporosis Study: Fracture Risk Prediction Based On Twenty Years Of Prospective Data.
Funder
National Health and Medical Research Council
Funding Amount
$1,107,758.00
Summary
In this population-based study we will generate evidence, both environmental and genetic, for defining fracture risk in Australian men and women. This will help identify individuals likely to sustain fragility fractures so that suitable therapies can be recommended. The data will be useful for developing prognostic models in both a clinical setting and for genetic screening programmes.
The feasibility, acceptability and cost-effectiveness of nurse-led models of chronic disease management in general practice. This study directly relates to the National Research Priority of 'promoting and maintaining good health' through our approach to trial a new and innovative model of chronic disease management specifically for CVD and Type II diabetes in general practice. This project aims to test a new model of health service delivery - that is, the use of a practice nurse to provide chro ....The feasibility, acceptability and cost-effectiveness of nurse-led models of chronic disease management in general practice. This study directly relates to the National Research Priority of 'promoting and maintaining good health' through our approach to trial a new and innovative model of chronic disease management specifically for CVD and Type II diabetes in general practice. This project aims to test a new model of health service delivery - that is, the use of a practice nurse to provide chronic disease care rather than a general practitioner. Our strategy involves collaboration with health providers, stakeholders and consumers to help achieve this by providing patient education and disease management through a registered nurse in general practice.Read moreRead less
Pathways to healing: determining effective care pathways for chronic wounds for timely healing, prevention and cost effectiveness. Care for chronic leg ulcers is reported to cost 1-2.5% of total health budgets (>3 billion $US/year, $500 million AUD/year). Efficient use of health resources and improved health as a result of effective chronic wound management (early healing and prevention) are the most significant potential outcomes from this study. In addition to direct health care costs, chronic ....Pathways to healing: determining effective care pathways for chronic wounds for timely healing, prevention and cost effectiveness. Care for chronic leg ulcers is reported to cost 1-2.5% of total health budgets (>3 billion $US/year, $500 million AUD/year). Efficient use of health resources and improved health as a result of effective chronic wound management (early healing and prevention) are the most significant potential outcomes from this study. In addition to direct health care costs, chronic wounds are associated with significant hidden burdens on the community resulting from loss of mobility, decreased functional ability, social isolation and loss of participation in the workforce/society. This study will provide much needed information on management of this chronic disease to promote improved quality of life, health and independence in this population.Read moreRead less
A Randomised Controlled Trial Of Interventional Versus Conservative Treatment Of Primary Spontaneous Pneumothorax
Funder
National Health and Medical Research Council
Funding Amount
$412,315.00
Summary
Primary spontaneous pneumothorax (PSP) is a collapsed lung that occurs in otherwise healthy people without underlying lung disease. Current standard treatment is to insert a chest drain into the chest to remove the air around the collapsed lung so that the lung re-inflates rapidly ("interventional treatment"). We will determine whether doing nothing, i.e. letting the lung re-inflate slowly on its own over several weeks ("conservative treatment"), is just as good or even better for patients.
Understanding Tendon Response to Sport and Exercise: Implications for Optimising Training, Injury Prevention and Accelerated Rehabilitation. This research will use frontier technologies to establish the effect of physical activity on tendon adaptation and injury. It will address National Research Priorities and lead to contemporary evidence-based physical activity practices to optimise health and fitness, prevent injury, and expedite rehabilitation after injury. Given the significant national in ....Understanding Tendon Response to Sport and Exercise: Implications for Optimising Training, Injury Prevention and Accelerated Rehabilitation. This research will use frontier technologies to establish the effect of physical activity on tendon adaptation and injury. It will address National Research Priorities and lead to contemporary evidence-based physical activity practices to optimise health and fitness, prevent injury, and expedite rehabilitation after injury. Given the significant national investment in sport, the rise in obesity, and the immense cost of sedentary behaviour and sport-related injuries, this research will have applications for enhancing physical activity recommendations that maintain health for all Australians. It will enhance Australia's leading position in international sport and sport science research and have beneficial applications for occupational health.Read moreRead less
Re-EValuating The Inhibition Of Stress Erosions (REVISE): Gastrointestinal Bleeding Prophylaxis In ICU
Funder
National Health and Medical Research Council
Funding Amount
$2,955,164.00
Summary
Around 50,000 patients in Australian Intensive Care Units receive a drug called pantoprazole each year with the aim of preventing bleeding from the gut. Recent research suggests this practice is ineffective and may harm patients by increasing their risk of serious infections. We will perform a definitive study to determine whether the widespread use of pantoprazole is beneficial or harmful.
Citizen engagement: Listening to citizens' views about Australia's health system and prevention. This project will yield new and important perspectives from citizens on preventive health and health promotion, which can be used to develop better targeted and more effective prevention and promotion policies and strategies. Citizens views will be investigated in relation to vexed issues such as: new approaches to financing and program delivery, reorienting the health insurance sector, reorienting ....Citizen engagement: Listening to citizens' views about Australia's health system and prevention. This project will yield new and important perspectives from citizens on preventive health and health promotion, which can be used to develop better targeted and more effective prevention and promotion policies and strategies. Citizens views will be investigated in relation to vexed issues such as: new approaches to financing and program delivery, reorienting the health insurance sector, reorienting the health system to focus more on prevention and health promotion, improving current approaches of consumer participation in prevention and chronic disease management, tackling broader issues in public policy trade-offs between health and non-health, diversifying workforce roles and involving health professionals in prevention and promotion.Read moreRead less
Long term economic impacts of disease on older workers to 2030: Costs to government and individuals and opportunities for intervention. This project will fill substantial gaps in Australian evidence about the health conditions of the future that will keep older workers out of the labour market and diminish their own immediate and long-term livings standards, thereby reducing funds available to government. We will address one of the most significant issues resulting from the fundamental changes t ....Long term economic impacts of disease on older workers to 2030: Costs to government and individuals and opportunities for intervention. This project will fill substantial gaps in Australian evidence about the health conditions of the future that will keep older workers out of the labour market and diminish their own immediate and long-term livings standards, thereby reducing funds available to government. We will address one of the most significant issues resulting from the fundamental changes to the demography of the Australian labour market and one that is regularly raised by the government following the release of the 2002 and 2007 Intergenerational Reports. This project will also examine the interventions that would improve the health of older workers and increase labour force participation over the long term.Read moreRead less
Planning female and male vaccination and cervical screening strategies to achieve optimal prevention of HPV-related disease. The findings from this research will inform the development of public health policy on the most cost-effective utilisation of resources for preventing cervical, anogenital and head/neck cancers, and genital warts, in women and men, due to human papillomavirus (HPV). We will evaluate strategies for using emerging screening and vaccine technologies to prevent HPV-related dis ....Planning female and male vaccination and cervical screening strategies to achieve optimal prevention of HPV-related disease. The findings from this research will inform the development of public health policy on the most cost-effective utilisation of resources for preventing cervical, anogenital and head/neck cancers, and genital warts, in women and men, due to human papillomavirus (HPV). We will evaluate strategies for using emerging screening and vaccine technologies to prevent HPV-related disease, and assess potential adverse outcomes of vaccination. Men are currently not covered by routine vaccination or screening programs; this research will assess the benefit to men of vaccinating women only, and will consider the impact of vaccination and other interventions targeted towards men.Read moreRead less
The Darwin Prospective Melioidosis Study: Years 27-31
Funder
National Health and Medical Research Council
Funding Amount
$1,281,718.00
Summary
The Darwin Prospective Melioidosis Study has documented 914 cases since 1989, with 115 fatalities. A surge in Darwin melioidosis cases over the past 5 years has been linked to urban development and the discovery of a new bacterial strain. Whole genome sequencing of our unique 25+ year set of bacteria and their linked patient data will unravel the changing epidemiology and identify important virulence factors, forming a foundation for future diagnostics, therapeutics, and vaccines.