Germ Cell Development In The Postnatal Testis: The Key To Early Surgery To Prevent Infertility And Malignancy In Cryptorchidism
Funder
National Health and Medical Research Council
Funding Amount
$725,326.00
Summary
The germ cells have been studied very extensively before birth or after puberty, but little is known about what happens shortly after birth. In children with undescended testes, early germ cell development is deranged, and this may be the key to find the right time for surgery to prevent subsequent infertility and risk of cancer. This project proposes some novel hypotheses to explain this and the studies aim to obtain the evidence to support surgery in the first 3-6 months of life..
Randomised Controlled Trial Of Surgical Skin Preparation For Prevention Of Superficial Wound Complications In Prosthetic Hip And Knee Replacement Surgery
Funder
National Health and Medical Research Council
Funding Amount
$403,128.00
Summary
The demand for prosthetic joint replacement surgery will double over the next decade. Complications involving the surgical wound are a devastating complication of this surgery. This randomised controlled trial aims to investigate whether skin cleansing prior to surgical incision with alcoholic iodine reduces the number of patients with superficial wound complications when compared to alcoholic chlorhexidine. The study will be performed in patients undergoing orthopaedic joint replacement surgery ....The demand for prosthetic joint replacement surgery will double over the next decade. Complications involving the surgical wound are a devastating complication of this surgery. This randomised controlled trial aims to investigate whether skin cleansing prior to surgical incision with alcoholic iodine reduces the number of patients with superficial wound complications when compared to alcoholic chlorhexidine. The study will be performed in patients undergoing orthopaedic joint replacement surgery: a high volume, high cost surgery.Read moreRead less