N-glycan Profiling As A Risk Stratification Biomarker For Type 2 Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$549,644.00
Summary
This study sets out to establish an N-glycan biomarker profile of suboptimal health in a well-established cohort of adult Australians, the Busselton Healthy Ageing Study (BHAS) and Chinese (SHS cohort) . This biomarker profile will contribute to the future development of N-glycan traits as a tool for (i) risk prediction of chronic disease onset, in particular those chronic conditions that constitute type II diabetes mellitus, and (ii) the prediction of a patient’s response to treatment.
Understanding The Impact Of Social, Economic And Geographic Disadvantage On The Health Of Australians In Mid - Later Lif
Funder
National Health and Medical Research Council
Funding Amount
$1,943,571.00
Summary
This research will examine the ways in which social, economic and environmental factors contribute to the health of Australians in mid to later life. It will help identify ways in which policy and preventive programs can contribute to improving health in mid to later life particularly among disadvantaged Australians. We will explore in detail social, economic and environmental factors in 100,000 people aged 45 and over; this will be the largest study of its kind ever undertaken in Australia. We ....This research will examine the ways in which social, economic and environmental factors contribute to the health of Australians in mid to later life. It will help identify ways in which policy and preventive programs can contribute to improving health in mid to later life particularly among disadvantaged Australians. We will explore in detail social, economic and environmental factors in 100,000 people aged 45 and over; this will be the largest study of its kind ever undertaken in Australia. We will examine the relationship between these social, economic factors, and lifestyle factors such as smoking, physical activity, environmental and obesity. This will enable us to identify where programs and policies should be directed to most rapidly improve the health of disadvantaged Australians.Read moreRead less
Cost Effectiveness Of Salt Reduction Interventions In Pacific Islands
Funder
National Health and Medical Research Council
Funding Amount
$1,045,593.00
Summary
This project will assess the impact and cost effectiveness of interventions to reduce salt intake in Fiji and Samoa. Precise data on salt consumption patterns amongst selected groups of adults at baseline will inform the development of subsequent interventions which will focus on changing both the food supply and consumer knowledge and behaviour. Repeat monitoring using the same indicators on completion of the intervention will enable quantification of the impact and examination of likely criter ....This project will assess the impact and cost effectiveness of interventions to reduce salt intake in Fiji and Samoa. Precise data on salt consumption patterns amongst selected groups of adults at baseline will inform the development of subsequent interventions which will focus on changing both the food supply and consumer knowledge and behaviour. Repeat monitoring using the same indicators on completion of the intervention will enable quantification of the impact and examination of likely criteria for successful interventions.Read moreRead less
E-PREDICE Early Prevention Of Diabetes Complications In Europe
Funder
National Health and Medical Research Council
Funding Amount
$917,400.00
Summary
The e-PREDICE study will randomise 3000 people aged 45-74 with mild hyperglycaemia or early diabetes to treatment with intensive lifestyle modification alone, or plus metformin, or sitagliptin, or liraglutide, aiming to reduce diabetes eye, kidney and nerve damage. The Australian arm will be co-ordinated by the University of Sydney and other sites include Baker IDI Heart and Diabetes Institute, Royal Melbourne Hospital, St Vincent’s Hospital Melbourne and Royal Brisbane and Womens Hospital