A mental health "thermometer" to monitor and prevent adverse treatment outcomes and self-harm among psychiatric inpatients. Our project stands to prevent adverse outcomes in psychiatric patients. An estimated 660 000 people are admitted to psychiatric hospitals each year; 99 000 of these people are worse off following treatment (assuming a deterioration rate of 15 per cent). Since monitoring can halve that rate, if this project can halve the deterioration rate again, then 24 750 inpatients acr ....A mental health "thermometer" to monitor and prevent adverse treatment outcomes and self-harm among psychiatric inpatients. Our project stands to prevent adverse outcomes in psychiatric patients. An estimated 660 000 people are admitted to psychiatric hospitals each year; 99 000 of these people are worse off following treatment (assuming a deterioration rate of 15 per cent). Since monitoring can halve that rate, if this project can halve the deterioration rate again, then 24 750 inpatients across the nation would not be worse off after treatment representing an annual saving of nearly $19.2 million per annum and reduce the number of patients who fall into a cycle of admission and readmission. Further, although suicide occurs in less than one per cent of admissions, if this research is able to predict and then reduce the suicide rate by as little as 10 per cent, then 660 lives can be saved each year.Read moreRead less
Development of dense gas technology platforms for the formulation of oral vaccines. This project will aim to develop a technology platform that enables the formulation of vaccines that can be delivered orally and this research has the potential to radically change existing vaccination regimens. The availability of needle-free vaccination also has potential for considerable societal and economic impact in developing countries.
A new approach to reversing and preventing immune-mediated diseases. Chronic inflammatory diseases affect up to 20 per cent of Australians. These diseases reduce wellbeing and life potential and shorten lifespan. This project addresses the urgent need for effective therapies and focuses on developing strategies for disease cure and prevention.
Protecting young people from harm and injury: investigating the utility of a risk and protective framework. Serious injuries due to transport, violence and alcohol associated risk-taking are the main cause of teenage death. An innovative school course will be taught and evaluated that increases protecting others from risk, helping injured friends and promoting a connected environment where teachers and peers reach out to provide support.
Short sleep as a cause of obesity: a longitudinal examination of Australian children and adults. This project will examine whether short sleep durations predict weight gain and obesity in Australian children and adults. The findings will have potentially important implications for how obesity is treated and prevented in Australia.
Highly multiplexed rapid-analysis microarrays for early disease diagnosis. Molecular diagnostics are revolutionising the treatment of disease in hospitals by providing rapid and accurate identification of pathogens; saving costs, time and lives. This project will accelerate this revolution by combining new array technology from the University of Sydney with a proven multiplex method from the Sydney based company, AusDiagnostics.
The effect of a practice change intervention in increasing, on a network-wide basis, the provision of preventive care by community health clinicians. Community health services do not routinely deliver care that aims to decrease client health risk behaviours. The effectiveness of an intervention designed to enhance the delivery of such care will be examined.
From risk factor analysis to translation: multiple sclerosis and vitamin D deficiency. This research on multiple sclerosis will focus on its causes and lifestyle factors that affect it and will trial vitamin D supplementation as a treatment. Studies on vitamin D deficiency in healthy populations aim to develop new public health recommendations on sun exposure and vitamin D that balance risk of skin cancer against vitamin D deficiency.
Patients' preference for participation in patient safety activities. This study will identify patient and nurse perceptions of involving patients in patient safety activities. Priorities for implementing strategies to support patient participation in patient safety activities will be identified, which will influence both health policy and practice.
Mathematical modelling can provide vital information on the effectiveness and practical implementation of microbicides and vaccines against HIV. This project will produce mathematical models of the earliest stages of HIV infection suitable for investigation of the implementation of vaccines and microbicides. It will provide a framework to investigate why these interventions have performed poorly to date, and how these may be better implemented.