Assessing the mechanisms and dynamics of myelination in the brain. This project is expected to refine our understanding of brain plasticity by revealing how myelin plasticity optimises brain function in response to experience. Using a multidisciplinary approach incorporating animal studies, mathematical modelling and computational neuroscience, the project seeks to redefine our understanding of myelin remodelling using an entirely new integrated cell-to-system approach. The expected outcome is f ....Assessing the mechanisms and dynamics of myelination in the brain. This project is expected to refine our understanding of brain plasticity by revealing how myelin plasticity optimises brain function in response to experience. Using a multidisciplinary approach incorporating animal studies, mathematical modelling and computational neuroscience, the project seeks to redefine our understanding of myelin remodelling using an entirely new integrated cell-to-system approach. The expected outcome is fundamental knowledge revealing how myelination is dynamically regulated by neural activity throughout life. This may transform current understanding of neuroplasticity that could aid in the future development of strategies to improve brain health.Read moreRead less
Nonstochastic information flows in networked dynamical systems. Feedback control is a crucial element of manufacturing, vehicular and energy systems, and is needed to guarantee hard performance bounds in safety- and mission-critical environments. When these control systems are implemented over communication networks, the amount of information flowing through them becomes a critical determinant of performance. However, the nonprobabilistic control objectives make standard information theory inapp ....Nonstochastic information flows in networked dynamical systems. Feedback control is a crucial element of manufacturing, vehicular and energy systems, and is needed to guarantee hard performance bounds in safety- and mission-critical environments. When these control systems are implemented over communication networks, the amount of information flowing through them becomes a critical determinant of performance. However, the nonprobabilistic control objectives make standard information theory inapplicable. This project aims to develop a novel, nonstochastic theory of information in order to analyse and design networked dynamical systems that obey worst-case performance limits. This will yield robust, probability-free algorithms for distributed control, filtering and causality inference.Read moreRead less
Interactive learning for robots in human environments. This project aims to develop robots that can interact with and learn from humans to quickly and safely learn new skills. Recent advances in robotics and artificial intelligence are poised to transform our economy, workplaces and homes, and even the organisation of society, however these advances are limited by robots’ inability to learn and adapt in uncertain environments. The outcomes of this project are expected to include new validated me ....Interactive learning for robots in human environments. This project aims to develop robots that can interact with and learn from humans to quickly and safely learn new skills. Recent advances in robotics and artificial intelligence are poised to transform our economy, workplaces and homes, and even the organisation of society, however these advances are limited by robots’ inability to learn and adapt in uncertain environments. The outcomes of this project are expected to include new validated methods and frameworks to enable robots to be used by non-experts and to be quickly deployed in a variety of settings. This is anticipated to provide transformative benefits, improving safety and productivity in the workspace, and enabling improved comfort, convenience and quality of life in the home.Read moreRead less
Optimal Control of Multi-Object System. Better understanding of multi-object systems developed from this research, in particular, optimal control algorithms for multi-object systems have several significant socio-economic benefits. Application areas that benefits from our research include aerospace applications such as radar, sonar, guidance, navigation, and air traffic control and non-aerospace areas such as image processing, oceanography autonomous vehicles and robotics, remote sensing, and bi ....Optimal Control of Multi-Object System. Better understanding of multi-object systems developed from this research, in particular, optimal control algorithms for multi-object systems have several significant socio-economic benefits. Application areas that benefits from our research include aerospace applications such as radar, sonar, guidance, navigation, and air traffic control and non-aerospace areas such as image processing, oceanography autonomous vehicles and robotics, remote sensing, and biomedical research. The sensor network discipline also stand to benefit from the understanding of multi-object system and control framework. Read moreRead less
Real time optimisation by extremum seeking control and learning control. Optimal control technology provides the systematic design of systems that exhibit optimal behaviour, such as maximal productivity, best efficiency, minimal cost and best quality. Real time optimisation finds the solution of the optimal control in real time, relaxing requirements on the system knowledge. The proposed research will build on Australia's well-established strength in control and optimisation, and aim to establis ....Real time optimisation by extremum seeking control and learning control. Optimal control technology provides the systematic design of systems that exhibit optimal behaviour, such as maximal productivity, best efficiency, minimal cost and best quality. Real time optimisation finds the solution of the optimal control in real time, relaxing requirements on the system knowledge. The proposed research will build on Australia's well-established strength in control and optimisation, and aim to establish within Australia world-leading expertise in real time optimisation theories and applications. This will have direct benefits to the Australian economy through various engineering applications ranging from vehicle dynamics to emissions reduction to manufacturing process to efficiency improvement of power generation systems.Read moreRead less
Highly efficient electric power and value-added synthesis gas co-generation from methane with zero greenhouse gas emission. This project addresses a novel sealing-free solid oxide fuel cell system producing simultaneously synthesis gas and electricity from methane with zero greenhouse gas emission. The project aims to deliver economic benefits and contribute to environmental protection and increased employment opportunities.
Modelling, Identification and Control of Complex Networks. Australia has been well known for its leading research in systems and control and many real-world applications in, for instance, telecommunications, defence, power grids and life sciences. This project will further promote Australia's leading position in the emerging new research field - complex networks by theoretical breakthrough in modelling, identification and control of complex networks, and cutting-edge platform technology that can ....Modelling, Identification and Control of Complex Networks. Australia has been well known for its leading research in systems and control and many real-world applications in, for instance, telecommunications, defence, power grids and life sciences. This project will further promote Australia's leading position in the emerging new research field - complex networks by theoretical breakthrough in modelling, identification and control of complex networks, and cutting-edge platform technology that can help Australian energy industry to reduce greenhouse emissions. It will also result in education of the next generation research leaders in this emerging field.Read moreRead less
Genomic and molecular characterisation of a novel Australian leishmania pathogen. Leishmaniasis is the second most serious protozoal disease after malaria. This project will help characterise the first Leishmania species identified in Australia providing molecular tools to monitor the pathogen and a detailed assessment of any potential risk to human health. Comparative analysis with more pathogenic species will help identify genes and mechanisms that determine the progression of human disease le ....Genomic and molecular characterisation of a novel Australian leishmania pathogen. Leishmaniasis is the second most serious protozoal disease after malaria. This project will help characterise the first Leishmania species identified in Australia providing molecular tools to monitor the pathogen and a detailed assessment of any potential risk to human health. Comparative analysis with more pathogenic species will help identify genes and mechanisms that determine the progression of human disease leading to the potential identification of new drug and vaccine targets. The methodologies and expertise developed will be used will be available to other research groups working on infectious diseases.Read moreRead less
Increasing internet energy and cost efficiency by improving higher-layer protocols. Australians rely heavily on our telecommunications infrastructure due to our geographic dispersion. We are also very susceptible to climate change, given our reliance on agriculture. Information technology is consuming a rapidly increasing fraction of our power and our budget. This research will help to reverse both those trends, by finding novel and practical ways to use our infrastructure more efficiently, and ....Increasing internet energy and cost efficiency by improving higher-layer protocols. Australians rely heavily on our telecommunications infrastructure due to our geographic dispersion. We are also very susceptible to climate change, given our reliance on agriculture. Information technology is consuming a rapidly increasing fraction of our power and our budget. This research will help to reverse both those trends, by finding novel and practical ways to use our infrastructure more efficiently, and to minimise its energy use. This will enable the Australian telecommunications industry to provide better service (including to Australian industries and rural communities) at lower economic and environmental cost. This project will put Australia on the international stage as a leading contributor to energy-efficient internet technology.Read moreRead less
Networked control systems: harnessing an emerging technology. Drive-by-wire cars, fly-by-wire aircraft and sensor/actuator wireless networks in process and manufacturing industries are just a few examples of emerging networked control technologies that are currently reshaping our world. These technological advances have a vast potential to reduce the cost, weight and volume of engineered systems, simplify their maintenance and installation and their novel architectures and features may enable u ....Networked control systems: harnessing an emerging technology. Drive-by-wire cars, fly-by-wire aircraft and sensor/actuator wireless networks in process and manufacturing industries are just a few examples of emerging networked control technologies that are currently reshaping our world. These technological advances have a vast potential to reduce the cost, weight and volume of engineered systems, simplify their maintenance and installation and their novel architectures and features may enable us to address significant environmental and socio-economic challenges, such as an increased demand for energy and other limited resources. This project will develop a systematic design methodology for networked control systems that will be essential in ensuring that its full potential is exploited.Read moreRead less