Conducting Clinical Research In Chronic Kidney Disease
Funder
National Health and Medical Research Council
Funding Amount
$569,219.00
Summary
The burden of Chronic Kidney Disease (CKD) is large, increasing, and ultimately unsustainable. One in ten Australians have CKD which puts them at higher risk of cardiovascular disease and cancer, and a higher likelihood of an early death. CKD also has a negative impact on people's lifestyles and relationships. Practitioner Fellowship support will allow me relief from my clinical commitments to invest in promising lines of new enquiry to support people with CKD and their carers.
Molecular Imaging As A Critical Tool In Discovery Of The Basis Of Tumour Heterogeneity And Developing Novel Therapies To Overcome Therapeutic Resistance
Funder
National Health and Medical Research Council
Funding Amount
$467,961.00
Summary
Determining treatment options for cancer currently relies on the size and extent of tumour deposits on imaging, combined with a biopsy. However, this approach fails to recognise the ability of tumours to evolve components that are, or become, resistant to treatment. My laboratory uses advanced molecular imaging, targeted biopsies, animal models and genetic analysis to detect and understand the basis of such resistance and thereby develop new, targeted treatments to improve patient outcomes.