Australian plague locust population genetics and migratory behaviour. The project will allow improved monitoring and forecasting of locusts in Australia and thereby help prevent locust outbreaks. Benefits will arise directly through greater effectiveness in reducing locust damage to crops, and indirectly to Australian rural industry generally through the economic benefits of reduced losses and locust control costs. Environmental and social benefits will also arise from reduced, better targeted u ....Australian plague locust population genetics and migratory behaviour. The project will allow improved monitoring and forecasting of locusts in Australia and thereby help prevent locust outbreaks. Benefits will arise directly through greater effectiveness in reducing locust damage to crops, and indirectly to Australian rural industry generally through the economic benefits of reduced losses and locust control costs. Environmental and social benefits will also arise from reduced, better targeted use of chemical insecticides. This in turn can produce secondary economic benefits, e.g. through enhanced growth and profitability of the organic beef industry within the main locust-outbreak area. Read moreRead less
Regulation of Plant Development by Small RNAs. Understanding the roles of small RNAs and their pathways is a new field of research that is giving, and will continue to give profound insights into how multicellular organisms regulate gene expression at a genomic level. Research in this area has already led to RNA interference technology, by which almost any gene can be switched off, and there is considerable potential for other gene silencing and trait modification technologies to emerge. The pro ....Regulation of Plant Development by Small RNAs. Understanding the roles of small RNAs and their pathways is a new field of research that is giving, and will continue to give profound insights into how multicellular organisms regulate gene expression at a genomic level. Research in this area has already led to RNA interference technology, by which almost any gene can be switched off, and there is considerable potential for other gene silencing and trait modification technologies to emerge. The project will yield insights into fundamental biological processes which are expected to engender applications in agriculture and biotechnology. It will maintain and enhance Australia's position in this area.Read moreRead less
Small RNAs: what makes a plant, a plant. Understanding the roles of small RNAs and their pathways is a young field of research that is giving, and will continue to give, profound insights into how multicellular organisms regulate gene expression at a genomic level. Research in this area has already led to RNA interference technology, by which almost any gene can be switched off, and there is considerable potential for other gene silencing and trait modification technologies to emerge. The projec ....Small RNAs: what makes a plant, a plant. Understanding the roles of small RNAs and their pathways is a young field of research that is giving, and will continue to give, profound insights into how multicellular organisms regulate gene expression at a genomic level. Research in this area has already led to RNA interference technology, by which almost any gene can be switched off, and there is considerable potential for other gene silencing and trait modification technologies to emerge. The project will yield insights into fundamental biological processes which are expected to engender applications in agriculture and biotechnology. It will maintain and enhance Australia's position in this area.Read moreRead less
Does developmental noise have an epigenetic basis? One's ultimate phenotype is the result of a combination of genotype and environment, and includes a poorly understood component termed ?developmental noise?. The molecular basis of developmental noise remains unknown, but it appears to be established in early development and to be retained for the life of the organism. We propose that the molecular basis of developmental noise is the epigenetic state of the genome. The stochastic nature of th ....Does developmental noise have an epigenetic basis? One's ultimate phenotype is the result of a combination of genotype and environment, and includes a poorly understood component termed ?developmental noise?. The molecular basis of developmental noise remains unknown, but it appears to be established in early development and to be retained for the life of the organism. We propose that the molecular basis of developmental noise is the epigenetic state of the genome. The stochastic nature of the establishment of epigenetic state, combined with its heritability during mitosis, provides all the essential components for developmental noise. If our hypothesis proves correct, our work will have a major impact on the understanding of one of the most basic concepts in genetics.Read moreRead less
The future of fruit fly control: making the Sterile Insect Technique work for Queensland fruit fly. The future of fruit fly control in Australia lies in the Sterile Insect Technique (SIT): it is the only non-pesticide option that can totally eliminate pest populations. Millions of dollars have already been invested to establish an SIT program against Queensland fruit fly (Q-fly) in southern and eastern Australia, but this program is currently largely ineffective due to the poor performance of t ....The future of fruit fly control: making the Sterile Insect Technique work for Queensland fruit fly. The future of fruit fly control in Australia lies in the Sterile Insect Technique (SIT): it is the only non-pesticide option that can totally eliminate pest populations. Millions of dollars have already been invested to establish an SIT program against Queensland fruit fly (Q-fly) in southern and eastern Australia, but this program is currently largely ineffective due to the poor performance of the mass-reared sterile flies. This project will apply genetic, ecological and technical solutions to the problems facing the current Q-fly control program. Effective control of Q-fly will enhance the international competitiveness of Australia's horticultural industries.Read moreRead less
Fruit fly pests in northwestern Australia: invasion, hybridisation or evolution? In northwestern Australia, recent events suggest that a new and serious fruit fly pest is now present, wher previously none existed. Due to difficulties in accurate identification, we do not know whether these new pest fruit flies are endemic fruit flies that have changed their behaviour, invasions of Queensland fruit fly, or hybrids between them. This project will use DNA microsatellites to distinguish between th ....Fruit fly pests in northwestern Australia: invasion, hybridisation or evolution? In northwestern Australia, recent events suggest that a new and serious fruit fly pest is now present, wher previously none existed. Due to difficulties in accurate identification, we do not know whether these new pest fruit flies are endemic fruit flies that have changed their behaviour, invasions of Queensland fruit fly, or hybrids between them. This project will use DNA microsatellites to distinguish between these possibilities. It will also establish whether the different species involved are actually different species, or should be regarded merely as different races. Such distinctions are important both scientifically and for export quarantine purposes.Read moreRead less
Discovery of novel microRNA biogenesis and functional components. Discovery of novel microRNA components will provide new strategies for confronting a diverse array of challenges Australia faces, such as the increasing rates of certain cancers in our population, to stresses on our crop plants faced with environmental changes. The biological mechanisms underlying these disparate problems are unified by microRNA involvement in many instances. By finding microRNA controlling factors common to all h ....Discovery of novel microRNA biogenesis and functional components. Discovery of novel microRNA components will provide new strategies for confronting a diverse array of challenges Australia faces, such as the increasing rates of certain cancers in our population, to stresses on our crop plants faced with environmental changes. The biological mechanisms underlying these disparate problems are unified by microRNA involvement in many instances. By finding microRNA controlling factors common to all higher organisms, we expect our community will benefit from the increased knowledge base that will help our researchers adopt new strategies in fighting diseases and improving our agricultural industry.Read moreRead less
Sex and the dominant male determiner in Australia's true fruit flies (Diptera: Tephritidae). A novel method to separate male and female embryos of the Queensland fruit fly will enable discovery of the molecular switch that causes embryos to change from the female to the male developmental pathway when they carry a Y chromosome. The results will lead to major improvements in the control of horticultural pest insects.