Which Mental Activities And When For Dementia Prevention? The Four Nations Longitudinal Collaboration
Funder
National Health and Medical Research Council
Funding Amount
$183,218.00
Summary
We will examine the link between lifetime participation in complex mental activities and long term dementia risk in a level of detail not previously possible. Four major studies of brain health from around the world will join forces for the first time to determine which mental activities are most closely linked to protection from dementia, and when during the lifespan these are most important. Mental activity will be assessed using our recently published Lifetime of Experiences Questionnaire.
This program of research is firmly focussed on the basic mechanisms involved in normal functioning of cells and tissues, followed by a step by step process to understand the abnormal or the diseased. The disease states we are investigating involve the blood and blood vessels, and when there is malfunction it may contribute to conditions as diverse as atherosclerosis, thrombosis, inflammation and cancer. The program thus addresses the fundamentals of diseases which are responsible for most deaths ....This program of research is firmly focussed on the basic mechanisms involved in normal functioning of cells and tissues, followed by a step by step process to understand the abnormal or the diseased. The disease states we are investigating involve the blood and blood vessels, and when there is malfunction it may contribute to conditions as diverse as atherosclerosis, thrombosis, inflammation and cancer. The program thus addresses the fundamentals of diseases which are responsible for most deaths in our society. We will use technology which is proven to provide precise information, the molecular and biochemical processes responsible for cell function (or malfunction). However in each individual project there will be a clear path to a clinical use, diagnostic or therapeutic. Indeed in a number of the components of the program there are already potential treatments and diagnostics in development and trial.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346889
Funder
Australian Research Council
Funding Amount
$670,000.00
Summary
Optical fibre fabrication and characterisation facility for next-generation photonics research. Australia is a world leader in photonics, underpinning the future of information communications technologies. ICT research demands the next generation of optical fibres; requiring high precision, state-of-the-art fibre fabrication and characterization equipment for advanced research into new photonic materials and technologies. OFTC is the keystone supplier of application specific optical fibre to alm ....Optical fibre fabrication and characterisation facility for next-generation photonics research. Australia is a world leader in photonics, underpinning the future of information communications technologies. ICT research demands the next generation of optical fibres; requiring high precision, state-of-the-art fibre fabrication and characterization equipment for advanced research into new photonic materials and technologies. OFTC is the keystone supplier of application specific optical fibre to almost all photonics related research and developing industry in Australia. New equipment will enable OFTC to lead innovation and a high level of excellence in research in fundamental science, new technologies, new fibre including non-linear and photonic-bandgap, fibre devices, lasers and amplifiers, and support commercial development in Australia.Read moreRead less
Human-Unmanned Aerial Vehicle interactions: Making drones talk and listen. This project aims to develop audio technology to enable unmanned aerial vehicles or drones to hear, use speech and sound to communicate with humans, acoustically sense their surroundings and make them less noisy. This project expects to generate new knowledge in acoustic signal processing and its application in drones using innovative approaches, such as use of miniature microphone and loudspeaker arrays, and active noise ....Human-Unmanned Aerial Vehicle interactions: Making drones talk and listen. This project aims to develop audio technology to enable unmanned aerial vehicles or drones to hear, use speech and sound to communicate with humans, acoustically sense their surroundings and make them less noisy. This project expects to generate new knowledge in acoustic signal processing and its application in drones using innovative approaches, such as use of miniature microphone and loudspeaker arrays, and active noise control. Expected outcomes include development of new theories, Intellectual Property, with potential commercial value, and training of next generation researchers. This should provide significant benefits with applications in life saving, search and rescue operations, transportation of goods, and creation of 3D media.Read moreRead less
VHF wireless technologies for last-mile Internet access in regional Australia. One of Australia's most vexing social issues is the provision of the last-mile Internet connection in regional Australia. The BushLAN team will solve this problem at minimal cost by developing a cellular wireless local area network operating on the TV band I channels (45-70 MHz). We will do this by developing a wireless modem whose design takes into account the properties of radio propagation in the Australian enviro ....VHF wireless technologies for last-mile Internet access in regional Australia. One of Australia's most vexing social issues is the provision of the last-mile Internet connection in regional Australia. The BushLAN team will solve this problem at minimal cost by developing a cellular wireless local area network operating on the TV band I channels (45-70 MHz). We will do this by developing a wireless modem whose design takes into account the properties of radio propagation in the Australian environment. We are collaborating with Internet service providers in regional Australia to trial systems currently being developed. In the process we will develop a new technology that will provide training for young engineers.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347407
Funder
Australian Research Council
Funding Amount
$100,000.00
Summary
Infrastructure for wireless Internet technology development for rural Australia. Three nodes of a low-power, very-high frequency digital wireless network will be installed at two locations in the Australian National University and one location at the University of Canberra. An additional node will then be located a further distance away (> 50 kms) in the ACT. This network will allow the development of novel technology for moderate speed (>100 kbps) non-line of sight wireless Internet access o ....Infrastructure for wireless Internet technology development for rural Australia. Three nodes of a low-power, very-high frequency digital wireless network will be installed at two locations in the Australian National University and one location at the University of Canberra. An additional node will then be located a further distance away (> 50 kms) in the ACT. This network will allow the development of novel technology for moderate speed (>100 kbps) non-line of sight wireless Internet access over ranges of 3-100 km for potential use by regional Australian Internet providers. The network will also catalyse research and training in wireless communication technology , digital signal processing, and computer networking.Read moreRead less
Genomic Analysis Of DNA Binding And Gene Regulation By The Chromatin Remodelling Factor UBF
Funder
National Health and Medical Research Council
Funding Amount
$624,254.00
Summary
Synthesis of ribosomes, the cellular protein synthetic machinery, is the major anabolic event of a growing cell and is frequently dysregulated during disease such as cancer. This grant will examine a protein termed UBF that we think plays an important role in orchestrating the cellular response to dysregulated ribosome biogenesis. By understanding how UBF functions we hope to uncover novel therapeutic approaches to treat diseases associated with ribosome stress .
System Theoretical Aspects of Spatial Signal Processing. The aims of the project is to gain better understanding of spatial characteristics of wireless communication channels; and to apply spatial signal processing theory to design receivers for wireless systems. The expected outcomes of the projects are new system theory for spatial signal processing, a new spatial model to characterize wireless communication channels, categorize a relationship between scattering environment antenna spacing and ....System Theoretical Aspects of Spatial Signal Processing. The aims of the project is to gain better understanding of spatial characteristics of wireless communication channels; and to apply spatial signal processing theory to design receivers for wireless systems. The expected outcomes of the projects are new system theory for spatial signal processing, a new spatial model to characterize wireless communication channels, categorize a relationship between scattering environment antenna spacing and multi-element antenna system capacity, and novel use of multiple antennas to improve the performance of wireless systems. Success in this investigation could have wide applications in the development of future mobile and fixed wireless communication systems.Read moreRead less
Model-Based Approach to Adaptive Channel Coding and Estimation for Future Wireless Communication Systems. The project aims to maximise capacity, data rate and user mobility in wireless communication systems and will advance Australia's fundamental knowledge base in this field so that it stays at the forefront of international research in mobile communications. The application of research outcomes by the Australian telecommunications industry will improve the extent and quality of mobile networks ....Model-Based Approach to Adaptive Channel Coding and Estimation for Future Wireless Communication Systems. The project aims to maximise capacity, data rate and user mobility in wireless communication systems and will advance Australia's fundamental knowledge base in this field so that it stays at the forefront of international research in mobile communications. The application of research outcomes by the Australian telecommunications industry will improve the extent and quality of mobile networks, increasing network capacity and the number of mobile phone subscribers in Australia. This project will also optimise the use of mobile network resources (such as bandwidth and power) in next generation mobile networks, which in turn will result in faster and more reliable services such as wireless Internet access for business and private use.Read moreRead less
Image-based teleoperation of semi-autonomous robotic vehicles. This project will contribute strongly to Australia's robotic service industry in the development of semi-autonomous robotic inspection vehicles by; developing core technology in image-based teleoperation, training experts in the area, promoting the study of this topic within the Australian academia, and developing test facilities and prototype vehicles. Robotic inspection vehicles have the potential to replace direct human presence i ....Image-based teleoperation of semi-autonomous robotic vehicles. This project will contribute strongly to Australia's robotic service industry in the development of semi-autonomous robotic inspection vehicles by; developing core technology in image-based teleoperation, training experts in the area, promoting the study of this topic within the Australian academia, and developing test facilities and prototype vehicles. Robotic inspection vehicles have the potential to replace direct human presence in difficult, dangerous or simply uncomfortable inspection tasks such as; inspection of industrial pressure vessels, piping and conduits in factories or mines, undersea cabling, inspection of bridges, dams and other large scale civil buildings, amongst many other possibilities.Read moreRead less