Australian Laureate Fellowships - Grant ID: FL180100134
Funder
Australian Research Council
Funding Amount
$3,007,316.00
Summary
Deep earth cycles of carbon, water and nitrogen. This project aims to understand the roles of carbon, water and nitrogen in the development of plate tectonics as drivers of mantle evolution. Through improved understanding of the impact of melting on the deep earth cycles of carbon, water and nitrogen, this project intends to better understand how key elements are enriched towards economically viable concentrations. This project will generate knowledge of long-term benefit for decision-making in ....Deep earth cycles of carbon, water and nitrogen. This project aims to understand the roles of carbon, water and nitrogen in the development of plate tectonics as drivers of mantle evolution. Through improved understanding of the impact of melting on the deep earth cycles of carbon, water and nitrogen, this project intends to better understand how key elements are enriched towards economically viable concentrations. This project will generate knowledge of long-term benefit for decision-making in the minerals exploration industry and key government agencies. The project will establish a new generation of Australian scientists with a deep interdisciplinary understanding of earth sciences, and pave the way for eventual unification of plate tectonic with climate systems.Read moreRead less
The structure and geochemistry of mineral interfaces in Earth's mantle. The interfaces between mineral grains are critical in determining rock properties and behaviour, yet we know little about them. This project uses emerging nano-technologies to establish the structure, chemistry and energy characteristics of interfaces in rocks from Earth’s mantle that control fundamental Earth processes such as plate tectonics and melting. The expected outcomes include a new understanding on one of the funda ....The structure and geochemistry of mineral interfaces in Earth's mantle. The interfaces between mineral grains are critical in determining rock properties and behaviour, yet we know little about them. This project uses emerging nano-technologies to establish the structure, chemistry and energy characteristics of interfaces in rocks from Earth’s mantle that control fundamental Earth processes such as plate tectonics and melting. The expected outcomes include a new understanding on one of the fundamental controls on rock properties and an enhanced ability to predict and model rock behaviour. The project provides research training in innovative research methodologies, will strengthen Australia’s leadership in nano-geoscience and will provide new methodologies for advanced rock characterisation.Read moreRead less
Maximising accuracy and reliability of carbonate climate proxy archives. This project brings together expertise and cutting-edge methodology from different disciplines to identify the controls on the compositions of the shells and skeletons of marine organisms. The compositions of these materials are essential tools to reconstruct environmental conditions before modern climate records began. However, recent insights into how they form profoundly complicate and affect their interpretations.
The r ....Maximising accuracy and reliability of carbonate climate proxy archives. This project brings together expertise and cutting-edge methodology from different disciplines to identify the controls on the compositions of the shells and skeletons of marine organisms. The compositions of these materials are essential tools to reconstruct environmental conditions before modern climate records began. However, recent insights into how they form profoundly complicate and affect their interpretations.
The results will enable us to develop new, realistic models for the behaviour of chemical elements in these materials. This will significantly improve paleoclimate interpretations and provide critical benefit for protecting Australia’s marine resources in the future. Read moreRead less
Mechanisms of proxy uptake in biominerals. This project plans to combine nano-analytical and aquaculture methods to develop new models that improve the reliability of paleoclimate reconstructions. The compositions of shells and skeletal materials of marine invertebrates are essential archives for quantifying temperatures and environmental conditions before modern climate records began. However, their reliability relies on understanding their formation. Emerging knowledge from material sciences i ....Mechanisms of proxy uptake in biominerals. This project plans to combine nano-analytical and aquaculture methods to develop new models that improve the reliability of paleoclimate reconstructions. The compositions of shells and skeletal materials of marine invertebrates are essential archives for quantifying temperatures and environmental conditions before modern climate records began. However, their reliability relies on understanding their formation. Emerging knowledge from material sciences indicates that these biocarbonates form via transient precursors rather than direct precipitation from seawater, profoundly affecting their interpretation. This project plans to transfer this new understanding to the earth sciences using nanoscale analytical methods including in vitro geochemical partitioning experiments. This would enable realistic models for geochemical proxy behaviour to be developed, significantly improving paleoclimate interpretations and assessments of ocean acidification effects on marine calcifiers.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100035
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre in Critical Resources for the Future. The proposed ARC Training Centre in Critical Resources aims to train the next generation of geoscientists needed to enable resourcing of the transition to a high-tech, clean energy society. Training of PhD students and postdoctoral scientists will primarily focus on bridging the gap between mineral systems science, mineral exploration protocols and ore processing/metallurgical extraction. This will provide geoscientists with an essential ....ARC Training Centre in Critical Resources for the Future. The proposed ARC Training Centre in Critical Resources aims to train the next generation of geoscientists needed to enable resourcing of the transition to a high-tech, clean energy society. Training of PhD students and postdoctoral scientists will primarily focus on bridging the gap between mineral systems science, mineral exploration protocols and ore processing/metallurgical extraction. This will provide geoscientists with an essential understanding of the whole value chain of the critical resources of the future.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100054
Funder
Australian Research Council
Funding Amount
$1,341,398.00
Summary
Dedicated High-throughput 3D-Electron Diffractometer. This proposal aims to install the first dedicated high-throughput 3D-electron diffractometer in the Southern Hemisphere, and one of the first in the world. It will be able to rapidly solve the atomic-scale structures of molecules and materials for which this is now extremely difficult and time-consuming – or impossible – due to the inability to grow large enough crystals for traditional X-ray diffraction. It will thus provide a significant ad ....Dedicated High-throughput 3D-Electron Diffractometer. This proposal aims to install the first dedicated high-throughput 3D-electron diffractometer in the Southern Hemisphere, and one of the first in the world. It will be able to rapidly solve the atomic-scale structures of molecules and materials for which this is now extremely difficult and time-consuming – or impossible – due to the inability to grow large enough crystals for traditional X-ray diffraction. It will thus provide a significant advantage for chemists, physicists, biologists, geologists, and engineers who rely on detailed structural knowledge to rationally optimise the properties of their compounds, from pharmaceutical activity to carbon capture to superconductivity, to the substantial benefit of multiple national priority areas.Read moreRead less
Chemical staples and chemical probes to dissect dynamins cellular roles. Modulation of protein structure drives cellular function. Dynamin GTPase forms at least two macromolecular structures with different cellular functions. The drivers behind these different structures is unknown. In this project we will leverage our discoveries, and planned enhancements, of chemical biology probes that will modulate dynamin activity by inhibiting at three distinct sites, and one site that stimulates dynamin a ....Chemical staples and chemical probes to dissect dynamins cellular roles. Modulation of protein structure drives cellular function. Dynamin GTPase forms at least two macromolecular structures with different cellular functions. The drivers behind these different structures is unknown. In this project we will leverage our discoveries, and planned enhancements, of chemical biology probes that will modulate dynamin activity by inhibiting at three distinct sites, and one site that stimulates dynamin activity. It is known that Dynamin helices and rings are believed responsible for at least three in cell biological functions: in hormone, neutral and receptor internalisation; cellular mitosis and in actin dynamics. Prior to this work we have lacked the tools to understand the role of shape modulation of protein function.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100707
Funder
Australian Research Council
Funding Amount
$450,926.00
Summary
Towards a molecular fingerprint for human-specific endogenous retroviruses. This project aims to understand how ancient viral sequences resident in the human genome can contribute to cellular processes. Using a novel molecular toolbox that combines affinity-directed proximity labelling mass spectrometry and single molecule microscopy, this project will characterise the cellular fingerprint of a human endogenous retrovirus family HERV-K (HML-2). This fingerprint will comprehensively describe how ....Towards a molecular fingerprint for human-specific endogenous retroviruses. This project aims to understand how ancient viral sequences resident in the human genome can contribute to cellular processes. Using a novel molecular toolbox that combines affinity-directed proximity labelling mass spectrometry and single molecule microscopy, this project will characterise the cellular fingerprint of a human endogenous retrovirus family HERV-K (HML-2). This fingerprint will comprehensively describe how expressed HERV-K loci engage with the homeostasis network in human cells. This will provide significant benefits in the form of new knowledge concerning fundamental aspects of cellular homeostasis, and a state-of-the-art molecular biology toolbox ready to explore quantitatively the role of HERV-K in human health and disease.Read moreRead less