Wall Turbulence Drag: Physical Mechanisms and Practicable Control Strategies. The proposed research will build on Australia's well-established strengths in Fluid Mechanics, and aim to establish within Australia world-leading expertise in turbulence control and drag reduction technology. This will have direct benefits to the Australian economy through Tourism (among other industries) by reducing the adverse impact of rising fuel prices on long-distance air travel, on which Australia is disproport ....Wall Turbulence Drag: Physical Mechanisms and Practicable Control Strategies. The proposed research will build on Australia's well-established strengths in Fluid Mechanics, and aim to establish within Australia world-leading expertise in turbulence control and drag reduction technology. This will have direct benefits to the Australian economy through Tourism (among other industries) by reducing the adverse impact of rising fuel prices on long-distance air travel, on which Australia is disproportionately reliant due to its geographic isolation. Efficient turbulence control strategies will also lead to improved combustion processes, resulting in not only better fuel efficiency but also reduced CO2 and pollutant emissions.Read moreRead less
Advanced products through multiscale microstructure engineering. The metals manufacturing industry is one of the most important in Australia. Future growth and sustainability of the sector is critically dependent on the development of innovative metal products and materials.. In this program Australia's leading research group in metal manufacturing will develop new products and processes through the controlled manipulation of the microstructure at a number of levels: from nano scale to macro s ....Advanced products through multiscale microstructure engineering. The metals manufacturing industry is one of the most important in Australia. Future growth and sustainability of the sector is critically dependent on the development of innovative metal products and materials.. In this program Australia's leading research group in metal manufacturing will develop new products and processes through the controlled manipulation of the microstructure at a number of levels: from nano scale to macro scale. The areas of application include the automotive industry, biomaterials, surface engineering and the emerging area of microforming technologiesRead moreRead less
Molecular machines that drive microbial pathogens. We will provide a comprehensive understanding of molecular machines situated at the surface of bacteria. This ground-breaking research will provide excellent outcomes in the training of research students and staff: this project entails frontier technology, and the transfer of technological capabilities not currently available in Australia. Our study on a non-pathogenic species of bacteria is timely too for National security: related species of b ....Molecular machines that drive microbial pathogens. We will provide a comprehensive understanding of molecular machines situated at the surface of bacteria. This ground-breaking research will provide excellent outcomes in the training of research students and staff: this project entails frontier technology, and the transfer of technological capabilities not currently available in Australia. Our study on a non-pathogenic species of bacteria is timely too for National security: related species of bacteria were amongst the first organisms trialed as biological weapons, and the pathogenic species remain rated as Class 3 organisms by the Centers for Disease Control.Read moreRead less
Molecular control of apoptosis and protein homeostasis. A million cells are produced every second by cell division. At the same time a million cells commit suicide by a process called apoptosis. When cells fail to die when they should they can develop into cancers. In heart attacks, stroke and neurodegenerative diseases, many cells appear to activate their self destruct mechanism to die unnecessarily. Drugs that can cause cancer cells to kill themselves, or drugs that prevent cells dying when th ....Molecular control of apoptosis and protein homeostasis. A million cells are produced every second by cell division. At the same time a million cells commit suicide by a process called apoptosis. When cells fail to die when they should they can develop into cancers. In heart attacks, stroke and neurodegenerative diseases, many cells appear to activate their self destruct mechanism to die unnecessarily. Drugs that can cause cancer cells to kill themselves, or drugs that prevent cells dying when they shouldn't, would make a major impact on many important diseases. Understanding the molecular mechanisms of cell death is the first step towards developing these drugs.Read moreRead less
Design in Nanostructured Materials - Formation and Stability of Nanostructure in Light Alloys and Light Metal Hybrids. Under its Light Metals Action Agenda, Australia recognizes a strategic interest in the production, processing and applications of the light metals, and a growth in global markets for light metals technology. Light metals research is a designated national priority, and this program will advance an established international leadership in the design and downstream processing of the ....Design in Nanostructured Materials - Formation and Stability of Nanostructure in Light Alloys and Light Metal Hybrids. Under its Light Metals Action Agenda, Australia recognizes a strategic interest in the production, processing and applications of the light metals, and a growth in global markets for light metals technology. Light metals research is a designated national priority, and this program will advance an established international leadership in the design and downstream processing of the light alloys. It will also provide leadership in a new national research activity in light metal hybrid structures, targeted at innovation in materials design and the expansion of markets for the light metals. It will underpin major developments in the light metals industry nationally and globally, and extend linkages with major research centres internationally.Read moreRead less
In vivo imaging of the immune system in self tolerance and infectious disease. This proposal will introduce sophisticated imaging technology into our cutting-edge research program. Our approach will permit high resolution imaging of the immune response within an intact animal; currently not possible in Australia at the present time. The unique combination of technology and biological resources will significantly advance knowledge in key areas of basic immunology research. It will provide local ....In vivo imaging of the immune system in self tolerance and infectious disease. This proposal will introduce sophisticated imaging technology into our cutting-edge research program. Our approach will permit high resolution imaging of the immune response within an intact animal; currently not possible in Australia at the present time. The unique combination of technology and biological resources will significantly advance knowledge in key areas of basic immunology research. It will provide local researchers insights into how the body responds to infectious disease and immune-related disorders and be directly applicable to vaccine design. The facility and related research program will undoubtedly attract a team of top-level national and international scientists and students keen to work with this advanced technology.Read moreRead less