A terrestrial hot spring setting for the origin of life. This project aims to test the proposal that a terrestrial hot spring field could have been the setting for the origin of life, in preference over the currently favoured site at deep sea vents. The project will involve an integrated, and multi-disciplinary study of the rocks, fluids, and molecules that together make up ancient to modern hot spring systems, and experiments on prebiotic organic chemistry using early Earth materials. Results w ....A terrestrial hot spring setting for the origin of life. This project aims to test the proposal that a terrestrial hot spring field could have been the setting for the origin of life, in preference over the currently favoured site at deep sea vents. The project will involve an integrated, and multi-disciplinary study of the rocks, fluids, and molecules that together make up ancient to modern hot spring systems, and experiments on prebiotic organic chemistry using early Earth materials. Results will be used to develop a terrestrial origin of life setting and assist in the search for life on Mars.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100110
Funder
Australian Research Council
Funding Amount
$474,000.00
Summary
High Resolution Mass Spectrometer for Chemical Characterisation in WA. The aim of this proposal is to establish new high resolution mass spectrometry facilities for Western Australia which will support multiple areas of chemical, materials and environmental science. The proposed platform will address a major need for the separation and characterisation of molecules relevant to synthetic and natural products chemistry, advanced materials and environmental analyses. The facility will support a num ....High Resolution Mass Spectrometer for Chemical Characterisation in WA. The aim of this proposal is to establish new high resolution mass spectrometry facilities for Western Australia which will support multiple areas of chemical, materials and environmental science. The proposed platform will address a major need for the separation and characterisation of molecules relevant to synthetic and natural products chemistry, advanced materials and environmental analyses. The facility will support a number of high impact ARC funded research projects in diverse areas, such as plant growth regulation, molecular electronics and environmental contaminants. The new instrumentation will be easy to use, provide advanced high quality data and overall benefit the next generation of researchers in Western Australia.Read moreRead less
Characterising the transport and delivery of oligonucleotides . Short RNA and DNA molecules represent a class of macromolecules that have great potential, but to facilitate their trafficking across cellular and membrane barriers into specific sites of action is challenging. This project aims to develop and apply novel imaging approaches to track them in cells and tissues. Expected outcomes include better understanding of the trafficking across cellular and membrane barriers, and improved imaging ....Characterising the transport and delivery of oligonucleotides . Short RNA and DNA molecules represent a class of macromolecules that have great potential, but to facilitate their trafficking across cellular and membrane barriers into specific sites of action is challenging. This project aims to develop and apply novel imaging approaches to track them in cells and tissues. Expected outcomes include better understanding of the trafficking across cellular and membrane barriers, and improved imaging tools that could be used to further study the molecular mechanisms of accumulation, metabolism and trafficking of these molecules. This project should provide new strategies to target these molecules to specific cells and tissues, which have significant social and economic benefits to the Australian community.Read moreRead less
Deciphering organelle transport mechanisms in plants. Plant growth, productivity and seed yield all depend on organelle function which requires metabolites and proteins
to be transported across membranes. This mechanism of transport is carried out by specific transporters that have
the ability to transport macromolecules, and regulate organelle function. We have identified new transporters that
are involved in amino acid and protein transport in the mitochondria, chloroplast and peroxisomes. We ....Deciphering organelle transport mechanisms in plants. Plant growth, productivity and seed yield all depend on organelle function which requires metabolites and proteins
to be transported across membranes. This mechanism of transport is carried out by specific transporters that have
the ability to transport macromolecules, and regulate organelle function. We have identified new transporters that
are involved in amino acid and protein transport in the mitochondria, chloroplast and peroxisomes. We will assign
function to each protein and investigate the importance in regulating organelle biogenesis. This will allow us to
modulate plant energy production for optimal growth and to withstand abiotic stress, all of which have
agriculturally beneficial consequences. Read moreRead less
ARC Centre of Excellence for Innovations in Peptide and Protein Science. The ARC Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS) strives to build a critical understanding of peptides and proteins in order to unleash the potential of these biomolecules for human benefit. We will discover nature’s untapped reservoir of peptides and proteins, decode their structures and functions, and
develop enhanced synthetic technologies to address biology’s next grand challenge—the d ....ARC Centre of Excellence for Innovations in Peptide and Protein Science. The ARC Centre of Excellence for Innovations in Peptide and Protein Science (CIPPS) strives to build a critical understanding of peptides and proteins in order to unleash the potential of these biomolecules for human benefit. We will discover nature’s untapped reservoir of peptides and proteins, decode their structures and functions, and
develop enhanced synthetic technologies to address biology’s next grand challenge—the design of peptides and proteins for targeted scientific, agricultural, biotechnology, animal health and pharmaceutical applications. CIPPS will assemble leading researchers from diverse disciplines to create a sustainable national entity that will drive new Australian industries and train next generation researchers.Read moreRead less