Discovery Early Career Researcher Award - Grant ID: DE200100800
Funder
Australian Research Council
Funding Amount
$415,693.00
Summary
Legume meristem signalling peptides: an untapped niche. This project aims to characterise novel signalling peptides regulating legume stem cell niches to enhance molecular-genetic networks and uncover potential key targets for crop improvement. Legumes represent agricultural sustainability through their decreased fertiliser requirements resulting in reduced carbon and nitrogen footprints. However, their unique gene signalling networks are poorly understood in comparison to traditional cereal cro ....Legume meristem signalling peptides: an untapped niche. This project aims to characterise novel signalling peptides regulating legume stem cell niches to enhance molecular-genetic networks and uncover potential key targets for crop improvement. Legumes represent agricultural sustainability through their decreased fertiliser requirements resulting in reduced carbon and nitrogen footprints. However, their unique gene signalling networks are poorly understood in comparison to traditional cereal crops. The proposed research intends to generate new knowledge in peptide signalling, plant development and legume symbiosis using multidisciplinary techniques. Expected project outcomes will increase understanding of peptide signalling in legume growth and adaption with useful findings for crop enhancement.Read moreRead less
Circular Plant Proteins with Pharmaceutical Applications. The proposed research will develop methods for using plants as protein production factories. Initially I will use plants to create engineered cyclotides that incorporate peptides with proven therapeutic activity against cancer and multiple sclerosis. Successful production of therapeutic proteins in plants will benefit Australians by making treatments for these and other diseases more accessible. It also has the potential for a major econo ....Circular Plant Proteins with Pharmaceutical Applications. The proposed research will develop methods for using plants as protein production factories. Initially I will use plants to create engineered cyclotides that incorporate peptides with proven therapeutic activity against cancer and multiple sclerosis. Successful production of therapeutic proteins in plants will benefit Australians by making treatments for these and other diseases more accessible. It also has the potential for a major economic benefit from the sales of Australian-based drugs. This proposal will also provide outstanding research training for graduate students in multidisciplinary methods that constitute state-of the-art structural and plant molecular biology.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101570
Funder
Australian Research Council
Funding Amount
$352,000.00
Summary
Inducible hyper-expression as a tool for metabolic engineering. This project aims to develop methods to improve plant natural products yields and diversify the products manufactured from a wide array of plant species. Valuable plant metabolites, including chemotherapeutics and opiates, are usually synthesised in minute amounts and can be so complex they can’t be chemically manufactured, limiting their use and affordability. This project aims to develop an inducible system that confers hyper-elev ....Inducible hyper-expression as a tool for metabolic engineering. This project aims to develop methods to improve plant natural products yields and diversify the products manufactured from a wide array of plant species. Valuable plant metabolites, including chemotherapeutics and opiates, are usually synthesised in minute amounts and can be so complex they can’t be chemically manufactured, limiting their use and affordability. This project aims to develop an inducible system that confers hyper-elevated levels of gene expression and independent control of multiple genes involved in metabolite synthesis in the same host. This technology is expected to enable flexible multi-trait bio-factories to be developed.Read moreRead less
The genes and pathways regulated by the AMYB80 network are involved in Arabidopsis pollen development. Tapetum is the inner layer of an anther essential for pollen formation. The project will study tapetal AtMYB80 network regulating pollen development. Knowledge of the network will be important in developing means to protect crop yields against cold and drought. Regulation of AtMYB80 activity is being used to create hybrid crops of high productivity.
Industrial Transformation Training Centres - Grant ID: IC210100047
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Training Centre for Accelerated Future Crop Development . The Centre will create a new generation of leaders in the implementation of advanced gene and field technologies for the benefit of the Australian agriculture industry. We will build the workforce and foundations that will drive translation of breakthroughs in advanced breeding, phenotyping and genetic technologies into higher-yielding crops. This will increase productivity across the sector and create new markets. Our technical trai ....ARC Training Centre for Accelerated Future Crop Development . The Centre will create a new generation of leaders in the implementation of advanced gene and field technologies for the benefit of the Australian agriculture industry. We will build the workforce and foundations that will drive translation of breakthroughs in advanced breeding, phenotyping and genetic technologies into higher-yielding crops. This will increase productivity across the sector and create new markets. Our technical training programs for graduates, trainees and industry will interface with best evidence-based practices in the wider socio-economic, regulatory and environmental contexts. Coupled with community and stakeholder engagement, the Centre will redefine and secure Australia’s future in agriculture. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100784
Funder
Australian Research Council
Funding Amount
$365,058.00
Summary
Improving cereal grain quality using epigenetic regulators. The project aims to determine the epigenetic regulatory mechanisms that control cereal grain quality and yield under water-deficit and heat stress. The project will use next-generation sequencing to identify key epigenetic regulators and their functional target genes, which confer superior grain quality to elite genotypes under adverse environments. Project outcomes will benefit cereal breeding by providing more-tailored screening stra ....Improving cereal grain quality using epigenetic regulators. The project aims to determine the epigenetic regulatory mechanisms that control cereal grain quality and yield under water-deficit and heat stress. The project will use next-generation sequencing to identify key epigenetic regulators and their functional target genes, which confer superior grain quality to elite genotypes under adverse environments. Project outcomes will benefit cereal breeding by providing more-tailored screening strategies and superior parental germplasm with enhanced quality and yield. The development of nutritionally improved crops will benefit the Australian cereal industry and export opportunities.Read moreRead less
Novel methods for the production of micronutrient-enriched rice. The increasingly productive Australian rice industry generated AUD$1 billion revenue in 2012. By targeting a rice gene that we recently identified as a key regulator of iron uptake and transport, this project will produce high value, micronutrient-enriched rice grain to improve the nutritional health of people in Australia and throughout the world.
Ecophysiology of stem succulent halophytes subject to changes in salinity and water availability: distinguishing natural dynamics from potential mine-related impacts. This project contributes to the National Research Priority of an environmentally sustainable Australia. The project will underpin management strategies of vegetation in saline lakes/marshes; wetlands of national importance to biodiversity. Understanding the vegetation at the Fortescue Marshes will provide vital base-information for ....Ecophysiology of stem succulent halophytes subject to changes in salinity and water availability: distinguishing natural dynamics from potential mine-related impacts. This project contributes to the National Research Priority of an environmentally sustainable Australia. The project will underpin management strategies of vegetation in saline lakes/marshes; wetlands of national importance to biodiversity. Understanding the vegetation at the Fortescue Marshes will provide vital base-information for the future, and have flow-on benefits for improved strategies for revegetation of saline lands. Improvement of the publicly available Herbarium database on samphire species will also enable improved species identifications for conservation and/or rehabilitation efforts. The project will train a PhD student in an industry-relevant research area that is currently in high demand.Read moreRead less
Effects of environmental factors on ecophysiological performance in the toxic cyanobacterium Nodularia. Nodularia is a toxic cyanobacterium that causes problem blooms in Australian waters and worldwide. The effects of environmental conditions on physiological processes in Nodularia are poorly understood and information on the effects on macromolecular synthesis and photosynthesis in Nodularia is limited. This project is of fundamental biological importance, making a major contribution to under ....Effects of environmental factors on ecophysiological performance in the toxic cyanobacterium Nodularia. Nodularia is a toxic cyanobacterium that causes problem blooms in Australian waters and worldwide. The effects of environmental conditions on physiological processes in Nodularia are poorly understood and information on the effects on macromolecular synthesis and photosynthesis in Nodularia is limited. This project is of fundamental biological importance, making a major contribution to understanding the impacts of environmental conditions on the physiological performance and ecology of Nodularia. The research has significance, both nationally and internationally, for the prediction of algal blooms in coastal and estuarine ecosystems, and will increase our knowledge of the factors controlling growth and toxicity of Nodularia worldwide. Read moreRead less
Stomata functioning in halophytes for improved plant stress tolerance. This project aims to determine how halophytes balance photosynthesis and water loss under extreme soil conditions. Salinity and drought affect crop production. Plants’ ability to balance carbon dioxide uptake and water loss through stomata determines how they cope with stressors. Halophytes can achieve this balance at conditions that normally kill 99% of crops, but how they do so is unknown. This project will characterise the ....Stomata functioning in halophytes for improved plant stress tolerance. This project aims to determine how halophytes balance photosynthesis and water loss under extreme soil conditions. Salinity and drought affect crop production. Plants’ ability to balance carbon dioxide uptake and water loss through stomata determines how they cope with stressors. Halophytes can achieve this balance at conditions that normally kill 99% of crops, but how they do so is unknown. This project will characterise the transport systems mediating stomata function in halophytes and contribute to understanding the molecular and physiological basis of their operation. This should allow breeders to use this trait to improve crop performance under conditions of extreme salinity and drought.Read moreRead less