The protein O-glycosylation pathway of Neisseria: a model system for O-glycosylation of bacterial proteins with potential use in biotechnology. Proteins can be modified by the addition of sugar molecules. This process, called glycosylation, has been studied for some time in humans and other higher organisms, but is relatively new in the field of bacteria. This study will use the bacterium Neisseria as a model system for this process and work to harness the system for use in biotechnology.
HoliCOW - A holobiont strategy to uncover the core microbiome in cows. Human population growth is driving a rise in cattle production for food, which necessitates sustainable practices that simultaneously optimise animal nutrition while reducing methane emissions, a critical greenhouse gas. This project aims to unravel and exploit biological connections across the cow holobiont, which pertains to the feed cows eat, their bodily function and the microbes in their rumen. This project will leverage ....HoliCOW - A holobiont strategy to uncover the core microbiome in cows. Human population growth is driving a rise in cattle production for food, which necessitates sustainable practices that simultaneously optimise animal nutrition while reducing methane emissions, a critical greenhouse gas. This project aims to unravel and exploit biological connections across the cow holobiont, which pertains to the feed cows eat, their bodily function and the microbes in their rumen. This project will leverage multi-layered molecular data derived from the cow holobiont to identify, characterise and ultimately control the core rumen microbiome that causes methane production in animals. The outcome will be new knowledge to facilitate microbiome-based interventions that benefit animal production and reduce its carbon footprint.Read moreRead less