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Scheme : Discovery Projects
Australian State/Territory : NT
Research Topic : Psychiatric Genetics
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  • Funded Activity

    Discovery Projects - Grant ID: DP0343672

    Funder
    Australian Research Council
    Funding Amount
    $290,000.00
    Summary
    Engineering and expression of recombinant antibodies that interact with plant pathogenic phytoplasma membrane proteins - a model for phytoplasma disease management. . In Australia phytoplasmas are associated with serious diseases including papaya dieback and strawberry lethal yellows. Phytoplasmas cannot be cultured so there is a paucity of knowledge at the genomic level. We have identified the ABC Transporter and FtsH genes and expressed these phytoplasma membrane proteins (MP) in E. coli . We .... Engineering and expression of recombinant antibodies that interact with plant pathogenic phytoplasma membrane proteins - a model for phytoplasma disease management. . In Australia phytoplasmas are associated with serious diseases including papaya dieback and strawberry lethal yellows. Phytoplasmas cannot be cultured so there is a paucity of knowledge at the genomic level. We have identified the ABC Transporter and FtsH genes and expressed these phytoplasma membrane proteins (MP) in E. coli . We will generate antibody fragments that bind these MP and express them in tomato. We will analyse antibody expression in tomato and study their association with the phytoplasma membrane. Transgenic plants will be inoculated with phytoplasma and monitored for resistance. This work represents a major step towards engineering resistance to phytoplasmas.
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    Funded Activity

    Discovery Projects - Grant ID: DP0208516

    Funder
    Australian Research Council
    Funding Amount
    $101,000.00
    Summary
    Minimum sizes and habitat areas for viable populations. This project will address two critical issues in conservation biology: How large do wildlife populations need to be to ensure long-term persistence? How large an area needs to be preserved? At present, no such estimates exist for most species. I will develop realistic population viability analysis (PVA) models (encompassing all threats to persistence) on many bird, mammal, reptile, amphibian, invertebrate and plant species, and estimate the .... Minimum sizes and habitat areas for viable populations. This project will address two critical issues in conservation biology: How large do wildlife populations need to be to ensure long-term persistence? How large an area needs to be preserved? At present, no such estimates exist for most species. I will develop realistic population viability analysis (PVA) models (encompassing all threats to persistence) on many bird, mammal, reptile, amphibian, invertebrate and plant species, and estimate the minimum population sizes and habitat areas required for long-term survival. My prior research has validated the predictive accuracy of PVA. This research will deliver practical guidelines for managing threatened species.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP210103227

    Funder
    Australian Research Council
    Funding Amount
    $417,000.00
    Summary
    Can animal dispersal inform fire management for species conservation? This project aims to improve fire management for environmental outcomes in northern Australia. It will address a key knowledge gap in our understanding of the effects of fire on biodiversity, relating to the spatial pattern of fire in the landscape. This is important because changing patterns of fire are not only a risk to humans but have major effects on our environment. This project will involve researchers, environmental ma .... Can animal dispersal inform fire management for species conservation? This project aims to improve fire management for environmental outcomes in northern Australia. It will address a key knowledge gap in our understanding of the effects of fire on biodiversity, relating to the spatial pattern of fire in the landscape. This is important because changing patterns of fire are not only a risk to humans but have major effects on our environment. This project will involve researchers, environmental managers and indigenous land owners to design better fire management strategies for biodiversity. The key benefits include new knowledge and tools to better manage fire and address one of our major environmental challenges, the decline of native wildlife in northern Australia.
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