I am a consultant psychiatrist and clinical researcher. Over the last 15 years I have been trying to detect people at risk of development of schizophrenia and other psychotic disorders by the prospective identification of the prodromal phase of these diso
A Randomised Controlled Trial Of NMDA Antagonist, Memantine, For The Treatment Of Borderline Personality Disorder
Funder
National Health and Medical Research Council
Funding Amount
$993,067.00
Summary
Borderline Personality Disorder (BPD) affects 5.9% of Australians and is a poorly understood mental illness with no clear medication treatment. The key symptoms of BPD all stem from impaired cognitive processes. Our early data shows improvement of symptoms with memantine - a cognitive enhancing drug used in Alzheimer’s disease.We plan to conduct a clinical trial; giving either 20mg memantine or placebo to 150 people with BPD across 2 Victorian sites.
Early Intervention For Borderline Personality Disorder In Youth: A Randomised Controlled Trial.
Funder
National Health and Medical Research Council
Funding Amount
$709,932.00
Summary
Borderline Personality Disorder (BPD) is a severe mental disorder involving instability of emotions, impulse control, self-concept and interpersonal relationships. BPD arises during adolescence and has a suicide rate of 10%. This study investigates the most effective form of early intervention for BPD that improves the daily lives of individuals and reduces poor outcomes, such as deliberate self-harm. The findings will inform the dissemination of early intervention for BPD in the health system.
Mental Health Of Young People With Developmental Disabilities
Funder
National Health and Medical Research Council
Funding Amount
$5,622,916.00
Summary
Mental health problems of people with developmental disabilities are a substantial public health problem. A large Australian study shows that the problem begins early and persists without intervention. We will evaluate the Stepping Stones Triple P model of parenting early intervention after adding newly developed modules for specific causes of ID. The effectiveness of the program across three states will be evaluated.
Optimising The Motor Outcomes Of Infants With Cerebral Palsy Using Environmental And Goal Oriented Interventions
Funder
National Health and Medical Research Council
Funding Amount
$116,563.00
Summary
Cerebral palsy is the most common physical disability in childhood. Early diagnosis enables intervention when the brain is developing. Current early intervention has little impact on movement. This research tests the effectiveness of “goal-directed training” and enriched environments by: systematically reviewing literature, piloting the intervention, conducting a clinical trial and interviewing parents. Findings have the potential to improve the outcomes of the 700 new cases diagnosed each year.
Parent Education For The Treatment Of Severe Behaviour Problems In Children With Developmental Disabilities
Funder
National Health and Medical Research Council
Funding Amount
$116,220.00
Summary
Approximately 40% of children with developmental disabilities have severe behaviour problems (e.g., aggression, self-injury, property destruction, and extreme tantrums) (Einfeld and Tonge, 1996). The care of a child with such problems represents a significant burden to parents and society. One of the most promising treatments is functional communication training (FCT), which aims to reduce problem behaviours by improving the child's communication skills. Numerous studies have demonstrated the ef ....Approximately 40% of children with developmental disabilities have severe behaviour problems (e.g., aggression, self-injury, property destruction, and extreme tantrums) (Einfeld and Tonge, 1996). The care of a child with such problems represents a significant burden to parents and society. One of the most promising treatments is functional communication training (FCT), which aims to reduce problem behaviours by improving the child's communication skills. Numerous studies have demonstrated the effectiveness of FCT (Mirenda, 1997). Wacker et al. (1998) have shown that parents can be taught to use FCT, but these parents received individual consultations, which would seem to limit its practicality. Preliminary results from our current APEX grant suggest that parents can learn to implement this treatment in a group format, which is more practical from a public health perspective. However, it is currently unknown if group training is as effective as individual consultation. In the present application, we aim to compare these two ways of teaching parents how to use FCT. From a total sample of 36, the parents of 18 children will be randomly assigned to the group training format and 18 to the individual format. All parents will receive 12 hours of training on how to use FCT, either as part of a group of 3 families (mothers and-or fathers) in the clinic or on a one-to-one basis in the family home. Pre, post, and follow-up measures of problem behaviours will be used to address the research question: Is group training as effective as individual consultation? If so, we would have demonstrated a more practical way of teaching parents how to implement this evidence-based treatment for child behaviour problems.Read moreRead less
Early Detection And Early Intervention For Cerebral Palsy
Funder
National Health and Medical Research Council
Funding Amount
$2,088,220.00
Summary
Cerebral Palsy (CP) is Australia’s 5th expensive health condition. Early Detection and effective early interventions are vitally needed to improve long-term outcomes. This fellowship develops and tests novel interventions to optimise neuroplasticity by improving early detection and physical, cognitive, psychological and health outcomes in children with CP. Earlier accurate detection of CP will ensure effective treatments utilise critical periods of brain development.
Enhancing The Capacity Of Mental Health Services To Review, Personalise And Intervene Early Through Implementation Of Real-time Outcome Monitoring
Funder
National Health and Medical Research Council
Funding Amount
$181,065.00
Summary
By monitoring functioning and symptom changes experienced by severe mental illness patients in their living environments, mental health services can identify those experiencing decline earlier and hence deliver appropriate and timely interventions. However, monitoring is currently poorly implemented in Australian mental health services and inadequately supported by national policy. The applicant proposes to address this evidence-practice gap through a mobile phone-based monitoring system.
Labels Used By Young People To Describe Mental Disorders: Their Determinants And Impact On Stigma And Help-seeking.
Funder
National Health and Medical Research Council
Funding Amount
$108,234.00
Summary
When a young person first begins to experience a mental health problem, getting professional help as early as possible is recommended. However, it is unclear whether being able to label the problem correctly when they first become aware of it actually assists a young person in getting the help they need. This study will look at how over 3,000 young Australians labelled mental disorders and which labels were more likely to guide them in choosing the best kinds of professional help and treatment.