Discovery Early Career Researcher Award - Grant ID: DE200100692
Funder
Australian Research Council
Funding Amount
$417,842.00
Summary
Stopping in the Real World: Cognitive Architectures for Selective Stopping. Response inhibition is the ability to stop actions that are in progress but become no longer appropriate, such as halting an order to launch a missile strike when a civilian vehicle is detected. The project focuses on people’s ability to either stop all planned actions or selectively stop some actions while allowing others to occur. The goal is to develop methodology to reliably measure the time it takes to stop actions, ....Stopping in the Real World: Cognitive Architectures for Selective Stopping. Response inhibition is the ability to stop actions that are in progress but become no longer appropriate, such as halting an order to launch a missile strike when a civilian vehicle is detected. The project focuses on people’s ability to either stop all planned actions or selectively stop some actions while allowing others to occur. The goal is to develop methodology to reliably measure the time it takes to stop actions, investigate the psychological mechanisms involved in stopping, and develop tools for defence-related personnel and job selection. The project provides significant benefits by enabling the study of how response inhibition ensures that appropriate actions occur and how failures of inhibition result in inappropriate actions. Read moreRead less
Quantitative psychological theories for a dynamic world. . The dynamic world around us means we need to constantly adjust our decisions in light of ever-changing influences, both external (weather, traffic ...) and internal (fatigue, learning ...). This project aims to understand how these changes affect performance. This will have significance for basic science, and also practical benefits for applied psychology. This project will examine the dynamic nature of psychological processes in a range ....Quantitative psychological theories for a dynamic world. . The dynamic world around us means we need to constantly adjust our decisions in light of ever-changing influences, both external (weather, traffic ...) and internal (fatigue, learning ...). This project aims to understand how these changes affect performance. This will have significance for basic science, and also practical benefits for applied psychology. This project will examine the dynamic nature of psychological processes in a range of settings: simple decisions, consumer decisions, human-machine interactions, and team performance. Theory development will lead to improved understanding of underlying cognitive processes, and transforms the measurement of decisions, which is important for applied psychological investigations. Read moreRead less
A longitudinal study of neuropsychological and neuromotor effects of low level manganese exposure. This study will investigate the neuropsychological and neuromotor effects of low level exposure to mangenese particulate. Previous studies have indicated symptomology of high level exposure, but there is contention in the literature regarding the effects of low levels of exposure. Our aim is to refine measures of cumulative exposure and develop a more comprehensive and senstitive testing protocol t ....A longitudinal study of neuropsychological and neuromotor effects of low level manganese exposure. This study will investigate the neuropsychological and neuromotor effects of low level exposure to mangenese particulate. Previous studies have indicated symptomology of high level exposure, but there is contention in the literature regarding the effects of low levels of exposure. Our aim is to refine measures of cumulative exposure and develop a more comprehensive and senstitive testing protocol than has been reported thus far. These measures and protocols will be incorporated into a longitudinal design, which has not been conducted in research studies to date. In addition, a database of exposure variables will be developed to facilitate long-term, accurate research into the effects of the low levels of exposure.Read moreRead less
Choice models for learning and memory. Life is filled with familiar choices that often require quick decisions about objects in the environment and the contents of memory. This project examines how we learn to make rapid and accurate choices and how we quickly asses the level of confidence we have in recognition decisions based on our memories.
Cellular genomic approach to the pathogenesis of multiple sclerosis. This project compares the levels of gene usage in two important immune cell types between patients with multiple sclerosis and people who do not have the disease. It aims to identify the molecular basis for the disease, in order to identify new diagnostic, preventative and treatment options.
Efficacy Of Education And Advice Delivered By Text Message To Aid Smoking Cessation
Funder
National Health and Medical Research Council
Funding Amount
$538,395.00
Summary
A high proportion of smokers indicate a desire to stop smoking and report having made attempts to quit. However, most attempts are not successful and new methods are needed to support motivated smokers and improve success rates. This project evaluates the use of text messages to deliver advice and support to smokers motivated to stop smoking. We aim to understand if and how this promosing new intervention helps smokers to quit.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100006
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
An adaptable and dedicated linear accelerator for medical radiation research. Leading radiation scientists developing innovative methods and devices for treating cancer patients will collaborate in future research using this highly adaptable linear accelerator for medical radiation research. Innovations in tumour targeting, better patient safety, new medical devices and improved cancer outcomes are expected.
Ultrasound in muscle vascular research, and gene therapy. This project focuses on ultrasound and microbubbles for the imaging of microvascular blood flow patterns in skeletal muscle and as a modality for drug delivery. The aim is to develop and refine technology specifically for (i) assessment of muscle microvascular flow in health and disease, and for (ii) delivery of state-of-the art gene constructs to endothelial cells that control blood flow in the muscle microvasculature. We anticipate impr ....Ultrasound in muscle vascular research, and gene therapy. This project focuses on ultrasound and microbubbles for the imaging of microvascular blood flow patterns in skeletal muscle and as a modality for drug delivery. The aim is to develop and refine technology specifically for (i) assessment of muscle microvascular flow in health and disease, and for (ii) delivery of state-of-the art gene constructs to endothelial cells that control blood flow in the muscle microvasculature. We anticipate improved technology for early diagnosis of impairment in microvascular flow relevant to muscle insulin resistance and novel therapeutics that improve muscle microvascular blood flow applicable to the treatment of diabetes.Read moreRead less
Inherited determinants of cancer aetiology. Family history of cancer is a strong risk factor for many cancers. This project will aim to identify inherited factors influencing risk of developing cancer and those factors influencing the course of the disease and outcomes.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0452281
Funder
Australian Research Council
Funding Amount
$102,900.00
Summary
Muscle Vascular Research and Gene Therapy Using Ultrasound. We seek funds to set up a national facility for ultrasound in muscle vascular research and gene therapy. Ultrasound with microbubbles will be used for the imaging of muscle microvascular blood flow and as a delivery modality for gene constructs to endothelial cells that control blood flow. The technology has application to (i) the assessment and therapeutic treatment of impaired microvascular function as in diabetics; (ii) the assessmen ....Muscle Vascular Research and Gene Therapy Using Ultrasound. We seek funds to set up a national facility for ultrasound in muscle vascular research and gene therapy. Ultrasound with microbubbles will be used for the imaging of muscle microvascular blood flow and as a delivery modality for gene constructs to endothelial cells that control blood flow. The technology has application to (i) the assessment and therapeutic treatment of impaired microvascular function as in diabetics; (ii) the assessment of adaptation to physical training and (iii) the development of therapeutic agents used to treat diabetes. We anticipate improved technology that is fully characterized and novel therapeutics that improve microvascular blood flow.Read moreRead less