Using Mathematical Models To Assess The Impact Of Interventions To Reduce Sexually Transmitted Infections In Australia
Funder
National Health and Medical Research Council
Funding Amount
$562,276.00
Summary
Sexually transmitted infections (STIs) are an increasing public health problem in Australia. Australia's recent National Transmissible Infections Strategy identified chlamydia control, STI prevention in gay men and STIs in Aboriginal and Torres Strait Islander communities as priority areas. We propose to develop mathematical models of STI transmission and use these to help understand and identify the most cost-effective interventions to reduce the impact of STIs on Australian populations.
Optimising Cervical Screening After The Introduction Of HPV Vaccination In Australia: Modelling Of Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$316,089.00
Summary
This research project will aid decision-making about how best to perform cervical screening in Australia after the introduction of vaccination against the human papillomavirus (or HPV). The project will use computer simulation techniques to explore different scenarios for vaccination and screening and to determine the optimal approach. This project involves a group of international collaborators with expertise in a number of areas including cancer epidemiology, screening for cancer, and computer ....This research project will aid decision-making about how best to perform cervical screening in Australia after the introduction of vaccination against the human papillomavirus (or HPV). The project will use computer simulation techniques to explore different scenarios for vaccination and screening and to determine the optimal approach. This project involves a group of international collaborators with expertise in a number of areas including cancer epidemiology, screening for cancer, and computer simulation methods. HPV is the virus responsible for the development of cervical cancer, and clinical trials have demonstrated that HPV vaccines administered to adoloescent girls are very effective at preventing disease that might have led to cancer in the future. However, Australia currently has a very effective Pap smear screening program, and in the first phase after the introduction of vaccination it will be important for women to continue being screened as usual. In the long term, HPV vaccination is expected to reduce the need for Pap smears. The research will involve a very detailed simulation of how HPV is transmitted in the Australian population, and how this will change after vaccination. The simulation will address questions of importance for any future public HPV vaccination program, such as whether males should be vaccinated as well as females. The simulation will also be used to determine the optimal starting age and frequency of Pap smears in the future. The outcomes of the research will be very important for policy-makers. In the long term, this research will ensure that the best recommendations are formulated for the timing and frequency of Pap smears after HPV vaccination is introduced.Read moreRead less
The HIV Prevention Revolution: Measuring Outcomes And Maximising Effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$1,081,723.00
Summary
There have been extra-ordinary recent biomedical advances in HIV prevention. These present an opportunity to turn the HIV epidemic around. We will undertake implementation research to optimise the impact of the new tools at the population level. NSW has a detailed HIV strategy with explicit targets for reduction of HIV transmission over the period 2012 to 2020. Our research will guide optimum program delivery to drive new HIV infections down in Australia and other high income settings.
Evaluating Cancer Screening: Context, Evidence, Values And Ethics
Funder
National Health and Medical Research Council
Funding Amount
$572,460.00
Summary
The research and clinical communities are divided over whether certain forms of cancer screening do more harm than good. This project asks: What is the right thing to do about cancer screening now? Using robust qualitative methodologies, we will study real cases of cancer screening and analyse their ethical implications. Drawing on this data and analysis, we will produce tools to help policy-makers, consumers and professionals make good decisions about cancer screening in future.
Creating Sustainable Healthcare: Ensuring New Diagnostics Avoid Harms, Improve Outcomes, And Direct Resources Wisely
Funder
National Health and Medical Research Council
Funding Amount
$2,497,658.00
Summary
Novel imaging, biomarkers and genomic tests for risk assessment and early detection are emerging as major forces for change in clinical practice. While providing advances and new benefits for patients, new technologies can also have harmful, unintended consequences - overdiagnosis and overtreatment. This multidisciplinary CRE will investigate how to respond to emerging technologies to optimise health outcomes while avoiding harms and directing healthcare resources wisely.
The Validation Of A Culturally-specific Measure To Identify Depression In Aboriginal And Torres Strait Islander People With Or Without Chronic Disease
Funder
National Health and Medical Research Council
Funding Amount
$658,971.00
Summary
The project aims to determine whether a short, free-to-use, questionnaire about depression that has been adapted for use with Aboriginal and Torres Strait Islander people, accurately identifies depression in this population. Specifically we aim to test whether this measure is suitable for use in primary care settings with Aboriginal and Torres Strait Islander people with or without chronic disease.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453801
Funder
Australian Research Council
Funding Amount
$102,900.00
Summary
Asia/Pacific HIV/AIDS Database: Support for Regional Policy Research. HIV/AIDS is one of the greatest contemporary threats to global human security, and its rapid growth in parts of the Asia/Pacific region makes it a major concern for Australia. Appropriate responses to the threat require accurate and regularly updated policy information. The construction of an interactive HIV policy data bank will support considerable research in a number of disciplines directly relevant to HIV control. This pr ....Asia/Pacific HIV/AIDS Database: Support for Regional Policy Research. HIV/AIDS is one of the greatest contemporary threats to global human security, and its rapid growth in parts of the Asia/Pacific region makes it a major concern for Australia. Appropriate responses to the threat require accurate and regularly updated policy information. The construction of an interactive HIV policy data bank will support considerable research in a number of disciplines directly relevant to HIV control. This project draws on multiple sources to construct a research and policy tool which will be drawn on by the partner organizations in a variety of HIV-related research projects.
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The relationships between retail availability, peer smoking and tobacco purchase and consumption: a diary study of smoking behaviour. Despite multiple public health initiatives, smoking remains the leading preventable cause of death, costing the Australian community more than 19,000 lives each year. Public awareness of the dangers of smoking is high, yet around 19% of Australians continue to smoke. Social effects (e.g. the presence of nearby smokers) and the high retail availability of cigarette ....The relationships between retail availability, peer smoking and tobacco purchase and consumption: a diary study of smoking behaviour. Despite multiple public health initiatives, smoking remains the leading preventable cause of death, costing the Australian community more than 19,000 lives each year. Public awareness of the dangers of smoking is high, yet around 19% of Australians continue to smoke. Social effects (e.g. the presence of nearby smokers) and the high retail availability of cigarettes are likely to be associated with smoking rates and failed quit attempts, yet there is little research in this area. By providing a better understanding of the effect of these factors on smoking patterns, the study will suggest the most effective avenues for reducing the rate of smoking in Australia, and thus decreasing its substantial cost to individuals and the community.Read moreRead less
Moral Hazard and the Pharmaceutical Benefits Scheme. The extent and significance of moral hazard in the PBS is an issue of significance for all Australians. Pharmaceuticals are a central feature in maintaining the health of Australians and with factors such as an ageing population and technological advances the centrality of pharmaceuticals is likely to be consolidated One, if not the, major challenge will be how to provide pharmaceuticals efficiently, equitably and sustainably. If significant a ....Moral Hazard and the Pharmaceutical Benefits Scheme. The extent and significance of moral hazard in the PBS is an issue of significance for all Australians. Pharmaceuticals are a central feature in maintaining the health of Australians and with factors such as an ageing population and technological advances the centrality of pharmaceuticals is likely to be consolidated One, if not the, major challenge will be how to provide pharmaceuticals efficiently, equitably and sustainably. If significant and extensive, moral hazard potentially compromises PBS efficiency and threatens sustainability. The proposed project represents a significant empirical contribution to understanding the impact of moral hazard on the PBS and will make a significant contribution towards making the PBS sustainableRead moreRead less
Improving Maternal And Infant Outcomes: A Multicentre Randomised Controlled Trial Of Midwifery And Dental Intervention
Funder
National Health and Medical Research Council
Funding Amount
$457,724.00
Summary
Poor oral health during pregnancy can impact the health of the mother and baby. Yet, many expectant mothers are unaware of the implications of poor oral health. In Australia there is a lack of importance being placed on maternal oral health. The aim of this study is to determine the effectiveness of a new service which will promote maternal oral health through collaboration between midwives and dentists. We expect the new service will improve women's oral health, uptake of dental services and po ....Poor oral health during pregnancy can impact the health of the mother and baby. Yet, many expectant mothers are unaware of the implications of poor oral health. In Australia there is a lack of importance being placed on maternal oral health. The aim of this study is to determine the effectiveness of a new service which will promote maternal oral health through collaboration between midwives and dentists. We expect the new service will improve women's oral health, uptake of dental services and potentially improve pregnancy outcomes.Read moreRead less