Harnessing the power of oceans: anchors for floating energy devices. This project aims to establish a geotechnical design framework for shared anchoring systems subjected to multidirectional cyclic loading for large integrated arrays of floating wind turbines and floating wave energy converters. This is expected to facilitate new, economic foundation solutions, generating radical cost savings to help unlock Australia's renewable ocean energy resources. The project aims to utilise a blend of stat ....Harnessing the power of oceans: anchors for floating energy devices. This project aims to establish a geotechnical design framework for shared anchoring systems subjected to multidirectional cyclic loading for large integrated arrays of floating wind turbines and floating wave energy converters. This is expected to facilitate new, economic foundation solutions, generating radical cost savings to help unlock Australia's renewable ocean energy resources. The project aims to utilise a blend of state-of-the-art centrifuge modelling techniques and numerical modelling, incorporating an energy-based method and yield envelopes. This innovative methodology aims to establish a validated framework for understanding and predicting foundation performance under the complex load histories arising in renewable ocean energy applications.Read moreRead less
Novel wave energy foundation solutions to survive extreme loads. This project aims to develop an economic and efficient anchoring system for taut-moored wave energy converters to enable us to exploit sustainable wave energy resources. Australia’s potential near-shore wave energy resource is four times larger than the current total capacity of our installed power generation. But the development of ocean wave energy is presently hampered by expensive, traditional anchoring systems. Using better es ....Novel wave energy foundation solutions to survive extreme loads. This project aims to develop an economic and efficient anchoring system for taut-moored wave energy converters to enable us to exploit sustainable wave energy resources. Australia’s potential near-shore wave energy resource is four times larger than the current total capacity of our installed power generation. But the development of ocean wave energy is presently hampered by expensive, traditional anchoring systems. Using better estimation of extreme loads, the project will use multidisciplinary approaches to investigate unique anchoring concepts with the aim of developing novel strategies to avoid the most extreme loads and enabling optimum anchor design. The outcomes of the project are intended to help to deliver economically viable wave energy projects.Read moreRead less
Solutions for rapid penetration into sand for offshore energy installations. This project aims to develop a fundamental understanding of the response of saturated sand in seabeds during rapid penetration by offshore site investigation tools and foundation construction. The research is using innovative physical and advanced numerical modelling techniques to quantify the significant increase in sand resistance caused by rapid penetration, enabling reliable design and reducing risk of material fail ....Solutions for rapid penetration into sand for offshore energy installations. This project aims to develop a fundamental understanding of the response of saturated sand in seabeds during rapid penetration by offshore site investigation tools and foundation construction. The research is using innovative physical and advanced numerical modelling techniques to quantify the significant increase in sand resistance caused by rapid penetration, enabling reliable design and reducing risk of material failure associated with the high impact forces. Expected outcomes of the project include a conceptual framework and scientific-based design tool to predict the geotechnical performance of offshore installations. The research will provide the necessary scientific advances to install, moor and service offshore wind and wave energy devices more economically and efficiently.Read moreRead less
Improving the security of anchoring systems under extreme cyclones. This project aims to investigate the behaviour of anchoring systems under cyclonic loading and to innovate anchor designs to improve their security during extreme cyclones. Anchoring systems are increasingly playing the vital role of securing floating structures to extract ocean energies, but the current empirical knowledge and design method hinder confidence in engineering application. This project expects to advance the fundam ....Improving the security of anchoring systems under extreme cyclones. This project aims to investigate the behaviour of anchoring systems under cyclonic loading and to innovate anchor designs to improve their security during extreme cyclones. Anchoring systems are increasingly playing the vital role of securing floating structures to extract ocean energies, but the current empirical knowledge and design method hinder confidence in engineering application. This project expects to advance the fundamental scientific understanding of the geotechnical mechanism of anchors under cyclonic loading using innovative experimental and advanced numerical modelling. Outcomes will include quality first-hand data contributing to the knowledge base, innovative anchor designs and new scientific based design guidelines.Read moreRead less
A direct drive linear tube generator for ocean wave energy conversion. This project aims to investigate a direct drive linear electromagnetic generator system for the maximum wave energy conversion and frequency bandwidth. This system has a translator of a multiple degree of freedom non-linear oscillator system built with the Halbach ring array pattern and ferro-fluid bearings. To establish wave energy conversion science, this project will investigate the device, its integration with a buoy stru ....A direct drive linear tube generator for ocean wave energy conversion. This project aims to investigate a direct drive linear electromagnetic generator system for the maximum wave energy conversion and frequency bandwidth. This system has a translator of a multiple degree of freedom non-linear oscillator system built with the Halbach ring array pattern and ferro-fluid bearings. To establish wave energy conversion science, this project will investigate the device, its integration with a buoy structure under wave loadings and automatic control of power conversion and conditioning. The outcome could meet demands for wave energy conversion technologies that reduce power generation cost and emissions, benefiting the Australian economy and environment.Read moreRead less
Nonlinear spatial and spatiotemporal econometrics: theory with applications. Modern societies like Australia have major challenges in the forecasting, measuring and managing of risks associated with global economic and environmental/climate changes. These tasks require advanced econometric techniques in modelling and forecasting of complex nonlinear spatiotemporal variability in economic and social systems. This project will develop frontier econometric technologies that enable more accurate eco ....Nonlinear spatial and spatiotemporal econometrics: theory with applications. Modern societies like Australia have major challenges in the forecasting, measuring and managing of risks associated with global economic and environmental/climate changes. These tasks require advanced econometric techniques in modelling and forecasting of complex nonlinear spatiotemporal variability in economic and social systems. This project will develop frontier econometric technologies that enable more accurate economic and climate forecasts. The tools produced will provide Australia's scientists and policy-makers with a greater capacity to manage the risks associated with these challenges. A side-benefit of the research will be high-quality publications that enhance the nation's reputation in this cutting edge research.Read moreRead less
Nonlinear Panel Data Econometrics: Theory and Practice. This research addresses the ARC National Research Priorities Goal of 'An Environmentally Sustainable Australia', specifically 'Reducing and capturing emissions in transport and energy generation'. Avoiding, managing, and/or adapting to the climate change impacts is now the most pressing global environmental problem. This project will produce tangible and original insights into policy options for institutional adjustment to future climate ....Nonlinear Panel Data Econometrics: Theory and Practice. This research addresses the ARC National Research Priorities Goal of 'An Environmentally Sustainable Australia', specifically 'Reducing and capturing emissions in transport and energy generation'. Avoiding, managing, and/or adapting to the climate change impacts is now the most pressing global environmental problem. This project will produce tangible and original insights into policy options for institutional adjustment to future climate change in Australia; will provide insight into the scope for positive community behavioural change; and possible transformations in Australian social debate to maximise adaptive capacity. It will also strengthen and produce original conceptual approaches and research methods.Read moreRead less
ARC Financial Integrity Research Network. The integrity of the financial system is constantly under stress because of the development of ever more complex financial instruments, structures and strategies, and the associated research technologies that continues to accelerate worldwide. FIRN's vision is to harness the considerable strengths of Australia's internationally renowned finance, accounting and economics researchers into a research agenda to address issues concerning the integrity of the ....ARC Financial Integrity Research Network. The integrity of the financial system is constantly under stress because of the development of ever more complex financial instruments, structures and strategies, and the associated research technologies that continues to accelerate worldwide. FIRN's vision is to harness the considerable strengths of Australia's internationally renowned finance, accounting and economics researchers into a research agenda to address issues concerning the integrity of the financial system. It will enable Australian research in this area to match the scale and impact of similar research in other major international financial centres, and play an essential role in placing Australia among the world's leaders in financial markets related research.Read moreRead less
Melanoma Mutation Profiling For Personalised Treatment
Funder
National Health and Medical Research Council
Funding Amount
$571,191.00
Summary
Melanoma is an aggressive skin cancer, and the leading cause of skin cancer related deaths. Disease spread is difficult to detect and extremely difficult to cure. This bleak clinical outcome is changing with the development of personalised therapies which include small molecule inhibitors to treat metastatic melanoma. Here we seek to identify the spectrum of mutations in patient tumours and circulating tumour cells for advanced personalised treatment.
Identifying Glaucoma Risk Variants In The Norfolk Island Genetic Isolate
Funder
National Health and Medical Research Council
Funding Amount
$658,447.00
Summary
Primary open angle glaucoma is the most common form of glaucoma. In this project we will focus on the identification of functional genetic variants influencing development of this disorder, using a powerful whole exome sequencing approach in a large multigenerational pedigree from the Norfolk Island population isolate. The identification of genes influencing glaucoma development would provide invaluable clues to aid in defining the pathophysiology of this common disease.