The Healthy Brain Project: A Prospective Cohort Study To Examine How Later-life University Education May Affect The Trajectory Of Ageing-related Cognitive Decline
Funder
National Health and Medical Research Council
Funding Amount
$1,085,742.00
Summary
Previous research has indicated that higher levels of education in early adulthood are associated with lower risk for dementia in older adults. This world-first project will examine if older adults who undertake university education have reduced rates of age-related cognitive decline than older adults who do not undertake further education. This would support the notion that boosting cognitive reserve in later life is protective against age- and disease-related neurodegenerative change.
Improved electrophoretic analyser for water quality monitoring. This proposal will advance the Australian made Eco Detection portable electrophoretic analyser for autonomous monitoring of water chemistry - the Eco Sensor. We will re-design and miniaturise the fluidic manifold to reduce capital- and per-sample cost, increase the sensitivity of nutrients - nitrate and phospate - by 100-times in both fresh- and sea-waters, and develop new ultra-sensitive reagents for heavy metal detection at enviro ....Improved electrophoretic analyser for water quality monitoring. This proposal will advance the Australian made Eco Detection portable electrophoretic analyser for autonomous monitoring of water chemistry - the Eco Sensor. We will re-design and miniaturise the fluidic manifold to reduce capital- and per-sample cost, increase the sensitivity of nutrients - nitrate and phospate - by 100-times in both fresh- and sea-waters, and develop new ultra-sensitive reagents for heavy metal detection at environmentally regulated levels. This will provide a single platform for at-site near-real-time monitoring of water chemistry for agricultural, mining, water corporations and other industries that use and/or discharge water to the environment. Read moreRead less
Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of th ....Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of this complex inverse estuary system and its surrounding catchment. The new understanding of the sources, fluxes and fate of nutrients within the bay and the surrounding catchment, arising from this project, is expected to benefit management decision-making and establish a new standard in estuarine water quality investigation.Read moreRead less
Understanding climate and harvest induced changes in fish life histories. This project aims to quantify the cumulative impacts of harvest and climate change across marine fishes and ecosystems. The project expects to generate new knowledge in this area by coupling the rich biological information archived in fish ear bones, with targeted multi-generation experiments and predictive modelling. Expected outcomes include fundamental insights into how human-induced environmental change affects fish gr ....Understanding climate and harvest induced changes in fish life histories. This project aims to quantify the cumulative impacts of harvest and climate change across marine fishes and ecosystems. The project expects to generate new knowledge in this area by coupling the rich biological information archived in fish ear bones, with targeted multi-generation experiments and predictive modelling. Expected outcomes include fundamental insights into how human-induced environmental change affects fish growth and maturation, and a subsequent critical evaluation of the sensitivity of fisheries models to trends in these life-history traits. This should provide significant benefits to fisheries and ecosystem management, ensuring they remain productive and resilient in a time of rapid environmental change.Read moreRead less
Zooplankton and ocean productivity in a changing climate. The scarcity of iron in the Southern Ocean limits biological productivity and carbon uptake. There is currently very little Information on zooplankton iron content, yet available data points to high variability. This variability is leading to poor predictive outcomes for models of Southern Ocean iron and carbon cycling. Our project addresses this knowledge gap by quantifying zooplankton iron content and examining its biogeochemical and ec ....Zooplankton and ocean productivity in a changing climate. The scarcity of iron in the Southern Ocean limits biological productivity and carbon uptake. There is currently very little Information on zooplankton iron content, yet available data points to high variability. This variability is leading to poor predictive outcomes for models of Southern Ocean iron and carbon cycling. Our project addresses this knowledge gap by quantifying zooplankton iron content and examining its biogeochemical and ecological impact on Southern Ocean productivity. Developing an understanding of how iron is cycled through zooplankton will provide significant benefits including improved global models used to quantify current and future patterns of ocean productivity critical for environmental and economic predictions.Read moreRead less
Ecological-epidemiological models of feral swamp buffalo control in northern Australia. This research is locally, nationally and internationally significant because it 1) improves the capacity of the Northern Territory and its traditional aboriginal owners to manage together this prevalent species in an effort to minimise disturbance to native flora and fauna and to understand the long-term implications of continued proliferation, 2) provides a nationally relevant system to monitor and project t ....Ecological-epidemiological models of feral swamp buffalo control in northern Australia. This research is locally, nationally and internationally significant because it 1) improves the capacity of the Northern Territory and its traditional aboriginal owners to manage together this prevalent species in an effort to minimise disturbance to native flora and fauna and to understand the long-term implications of continued proliferation, 2) provides a nationally relevant system to monitor and project the spread of disease through feral animal populations in Australia, and 3) combines quantitative data and robust analytical tools that can be used as a template for solving many broad-scale feral animal problems around the world.Read moreRead less
A Game Changer? Alcohol and Women's Sport in Australia. This project aims to investigate emerging relationships between women and alcohol in Australian sport. We will examine the meanings that drinking may have for sportswomen and female fans, and identify new theoretical frameworks for rethinking drinking, gender and sport. In the context of public and policy debates about the risks and social impacts of alcohol consumption, we expect to generate significant new knowledge outcomes. These includ ....A Game Changer? Alcohol and Women's Sport in Australia. This project aims to investigate emerging relationships between women and alcohol in Australian sport. We will examine the meanings that drinking may have for sportswomen and female fans, and identify new theoretical frameworks for rethinking drinking, gender and sport. In the context of public and policy debates about the risks and social impacts of alcohol consumption, we expect to generate significant new knowledge outcomes. These include a world first research corpus of direct relevance for sports administrators and policy-makers, who are currently grappling with the costs and consequences of alcohol use in licensing and legislation, as well as in marketing, sponsorship and promotion of sport to women.Read moreRead less
Understanding multi-scale dynamics of eddies in the East Australian Current. This project aims to provide the first rigorous quantification of the complex dynamics of rotating eddies (the weather systems of the ocean) and fronts on scales ranging from metres to 100s of kilometres and hours to weeks in the East Australian Current System. This project is at the frontier of oceanographic research and will provide significant new understanding of the physical and biogeochemical dynamics of eddies an ....Understanding multi-scale dynamics of eddies in the East Australian Current. This project aims to provide the first rigorous quantification of the complex dynamics of rotating eddies (the weather systems of the ocean) and fronts on scales ranging from metres to 100s of kilometres and hours to weeks in the East Australian Current System. This project is at the frontier of oceanographic research and will provide significant new understanding of the physical and biogeochemical dynamics of eddies and their interactions across multiple spatio-temporal scales, revealing their impacts on productivity along Australia’s most populous coastline. This will provide significant benefits such as improved ocean forecasting and sustainable management of Australian marine industries and seafood sector, supporting economic growth. Read moreRead less
The Lively Regional City: Mapping City Centre ‘Assemblages’ that Work. This project analyses city centre revitalisation processes and policies in the context of regional Australia. Working with Wollongong City Council, the project aims to provide an evidence-based analysis of how the Wollongong city centre is perceived, regarded and used by its residents and visitors, paying particular attention to those aspects considered either 'lively' or 'dead'; its goal is to interrogate revitalisation poli ....The Lively Regional City: Mapping City Centre ‘Assemblages’ that Work. This project analyses city centre revitalisation processes and policies in the context of regional Australia. Working with Wollongong City Council, the project aims to provide an evidence-based analysis of how the Wollongong city centre is perceived, regarded and used by its residents and visitors, paying particular attention to those aspects considered either 'lively' or 'dead'; its goal is to interrogate revitalisation policy frameworks and create decision-making tools to inform planning processes for long-term city centre revitalisation and sustainable economic growth; and identify opportunities for innovative city centre planning in Wollongong to contribute to the regions sustainable transformation, long-term growth, employment and community development.Read moreRead less
Fire, air, water and earth: Using fossils to discover the evolution of Australia’s open vegetation. How Australia came to be dominated by open, tough-leaved vegetation is an old but still highly controversial question, especially with recent developments in molecular biology that challenge paradigms established from the fossil record. The project will test this new molecular paradigm with innovative use of characteristics of fossil leaves to identify the timing and drivers of the evolution of Au ....Fire, air, water and earth: Using fossils to discover the evolution of Australia’s open vegetation. How Australia came to be dominated by open, tough-leaved vegetation is an old but still highly controversial question, especially with recent developments in molecular biology that challenge paradigms established from the fossil record. The project will test this new molecular paradigm with innovative use of characteristics of fossil leaves to identify the timing and drivers of the evolution of Australia’s open vegetation. The integration of new and rigorous evidence derived from living and fossil plants will provide the clearest evidence yet for the origins of Australian environments. This has ramifications for understanding plant responses to past and future climate changes.Read moreRead less