A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Improving The Prevention, Treatment And Management Of Cardiovascular & Chronic Disease In The Community
Funder
National Health and Medical Research Council
Funding Amount
$774,540.00
Summary
The identification, prevention and management of cardiovascular and chronic disease risk factors and understanding impact on clinical outcomes is fundamental to improving health and well-being. The program of work encapsulated in this application utilises modern epidemiological research methods involving large scale clinical trials, registries and epidemiological modelling to advance our understanding and provide new directions for cardiovascular disease prevention and management.
QUality Improvement In Primary Care To Prevent Hospitalisations And Improve Effectiveness And Efficiency Of Care For People Living With Heart Disease (QUEL)
Funder
National Health and Medical Research Council
Funding Amount
$828,305.00
Summary
Heart disease accounts for a great number of deaths and admissions to hospital. We aim to improve ongoing prevention for people with heart disease by supporting general practices to use their data and provide more systematic care. We propose a randomised trial to determine whether a practice level strategy reduces cardiovascular events and hospitalisations and saves money. The research will directly inform government decision-making and policy regarding primary care incentive payment programs.
Developing An Australian Valuation For The EQ-5D-5L Quality Of Life Instrument
Funder
National Health and Medical Research Council
Funding Amount
$348,357.00
Summary
In the assessment of gains resulting from a health technology, it is standard to consider both mortality and quality of life effects. This project explores how Australians value different components of quality of life. To do this, we are running an online survey called a discrete choice experiment, and analysing the data using a range of cutting-edge econometric techniques. This will allow policy-makers to better reflect people's preferences when making decisions about new technologies.
Predicting pollutant dispersion within the CBD. The accidental or pre-meditated release of hazardous gases and aerosols within an urban environment are potentially threatening to human life and safety. Emergency responders require adequate information to quickly address these concerns yet the lack of detailed observations and the complex nature of the dispersion make this task difficult. This project will collect detailed observations of tracer dispersion within the Perth central business distri ....Predicting pollutant dispersion within the CBD. The accidental or pre-meditated release of hazardous gases and aerosols within an urban environment are potentially threatening to human life and safety. Emergency responders require adequate information to quickly address these concerns yet the lack of detailed observations and the complex nature of the dispersion make this task difficult. This project will collect detailed observations of tracer dispersion within the Perth central business district and combine these observations with multiscale modelling to redefine appropriate emergency response models as well as their limits. Such analysis will enhance mitigation strategies.Read moreRead less
Ecological regime shifts for re-engineering water pollution management. This project aims to validate a framework for the management of water pollution. As the world population increases, maintaining robust, cost-effective and environmentally safe water resources is important. This project will investigate environmental controls of toxin occurrence in urban and wastewater systems. The project is expected to mitigate deadly cyanotoxins, which threaten the safety of water resources, while a numeri ....Ecological regime shifts for re-engineering water pollution management. This project aims to validate a framework for the management of water pollution. As the world population increases, maintaining robust, cost-effective and environmentally safe water resources is important. This project will investigate environmental controls of toxin occurrence in urban and wastewater systems. The project is expected to mitigate deadly cyanotoxins, which threaten the safety of water resources, while a numerical ecological model will tackle water pollution issues in natural and engineered water systems.Read moreRead less
More bang for your carbon buck: carbon, biodiversity and water balance consequences of whole-catchment carbon farming. Farming carbon via tree plantings on pasture land is becoming increasingly common to address the effects of climate change. This activity is likely to produce dramatic changes in Australia's rural landscapes, but we have little knowledge of likely effects on crucial ecosystem services and attributes such as stream water yields and biodiversity. This project will investigate the ....More bang for your carbon buck: carbon, biodiversity and water balance consequences of whole-catchment carbon farming. Farming carbon via tree plantings on pasture land is becoming increasingly common to address the effects of climate change. This activity is likely to produce dramatic changes in Australia's rural landscapes, but we have little knowledge of likely effects on crucial ecosystem services and attributes such as stream water yields and biodiversity. This project will investigate the relationship between tree cover, carbon uptake, water yield and biodiversity. The outcomes will allow government agencies, landowners and carbon farming groups to better evaluate the effects of different landscape planning options and contribute to effective long-term planning for multiple goals.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775548
Funder
Australian Research Council
Funding Amount
$180,000.00
Summary
Advanced characterisation facilities for functional nanostructured materials. A critical factor that enhances frontier research is a set of advanced core research experimental facilities for material characterisation purposes. The proposed equipment aims to: (1) provide research facilities for advanced nanomaterial research; (2) improve national competitiveness and growth in a knowledge-based economy; and (3) foster local talented researchers in order to meet the strategic needs of the nation fo ....Advanced characterisation facilities for functional nanostructured materials. A critical factor that enhances frontier research is a set of advanced core research experimental facilities for material characterisation purposes. The proposed equipment aims to: (1) provide research facilities for advanced nanomaterial research; (2) improve national competitiveness and growth in a knowledge-based economy; and (3) foster local talented researchers in order to meet the strategic needs of the nation for a sustainable environment. These activities will revitalise Australia's leading role in creating new technologies with particular relevance to using advanced nanostructures for the production of clean air and water, and sustainable energy alternatives.Read moreRead less
National Centre Of Research Excellence To Improve Management Of Peripheral Arterial Disease
Funder
National Health and Medical Research Council
Funding Amount
$2,618,637.00
Summary
Approximately 15% of adults have blockages or weakness of major arteries in the periphery, associated with impaired quality of life and a high mortality. Significant management deficiencies for these problems include limited diagnostic, prognostic and treatment options, as well as poor adoption of evidence based practice. The proposed national centre will bring together a group of experts in the field to instigate a number of initiatives to improve patient management.
Immobilized biocatalysts on selected filter media to control odour emissions from wastewater treatment and composting facilities. Odour is one of the common problems faced by wastewater and solid waste industries as a result of public complaints about poor local air quality. Although odour removal technologies exist, they encounter a number of problems. The lack of harsh chemicals required for the proposed technology means there is no wastewater stream to treat. This will have an impact on the r ....Immobilized biocatalysts on selected filter media to control odour emissions from wastewater treatment and composting facilities. Odour is one of the common problems faced by wastewater and solid waste industries as a result of public complaints about poor local air quality. Although odour removal technologies exist, they encounter a number of problems. The lack of harsh chemicals required for the proposed technology means there is no wastewater stream to treat. This will have an impact on the reduction of chemicals disposed to the environment, preventing unnecessary contamination of land and water resources. The lower space requirement of the technology will free up land, formerly required for large biofilters, for other uses including civic amenities.Read moreRead less