Tracking The Impact Of Drug Regulatory Actions: Consumer Health Outcomes, Risk-benefit Issues And Policy Framework.
Funder
National Health and Medical Research Council
Funding Amount
$439,324.00
Summary
This study will explore what happens in the community when a medicine is withdrawn from the market or discredited due to safety concerns. It will examine the impacts of two recent cases of medicine withdrawal or serious long-term safety concern, on a large cohort of women with high utilisation rates who were monitored during the time the medicines were discredited. The study will be an important guide to future regulatory, media and provider responses when medicines are discredited.
Polypharmacy In Elderly Australians - Can Deprescribing Improve Health Related Outcomes And Reduce Costs?
Funder
National Health and Medical Research Council
Funding Amount
$344,644.00
Summary
Medications are often inappropriately prescribed in elderly Australians. This research investigates whether reducing certain classes of medications results in improved patient outcomes, and what the cost implications are of inappropriately prescribed medications and the costs of a service which reduces drug useage.
The Effect Of A Standardised Ginseng Extract In Patients With Moderate COPD: A Randomised, Double-blind Trial
Funder
National Health and Medical Research Council
Funding Amount
$581,296.00
Summary
Chronic obstructive pulmonary disease (COPD) is a major cause of mortality and morbidity. Current medical treatments are only symptomatic and are far from satisfatory. Many COPD patients use herbal medicines but evidence of effect is lacking. This study will determine the effect and safety of a standardised extract of Panax ginseng for patients with moderate COPD. The design of the study will combine rigorous randomised controlled trial methodology with Chinese medicine theory.
Developing A Framework To Evaluate Low Value Prescribing In The Australian Health Care Setting
Funder
National Health and Medical Research Council
Funding Amount
$124,608.00
Summary
The aim of this project is to develop a framework to evaluate the quality of prescribing in Australia using routinely collected administrative health data. Given growing concerns regarding the quality of prescribing of psychotropic medicines and opioids, these medicines will be e focus of the study. Patterns, quality markers and health and financial consequences of poor prescribing will be assessed.
Medicine-associated Dementia And Cognitive Impairment: Identifying The Problem, Reducing The Harm
Funder
National Health and Medical Research Council
Funding Amount
$513,116.00
Summary
Several studies have shown an association between use of anticholinergic or sedative medicines and increased risk of dementia. Questions remain about whether these medicines cause dementia (or are just used by people already at risk), whether or not cognitive function improves if the medicines are stopped or if the dose is reduced, and the characteristics of patients most likely to use these medicines. This program of research aims to answer these questions.