Unravelling the dominant drivers of ion specificity. This project aims to understand what governs the sensitivity of many technological and biological processes to the precise nature of the salt present in solution. The term ‘ion-specific’ encompasses all the circumstances in which the influence of a salt in solution depends on the precise chemical nature of the salt, not just the electrical charge on the ions that form the salt. As such, ion-specific effects abound and have important consequenc ....Unravelling the dominant drivers of ion specificity. This project aims to understand what governs the sensitivity of many technological and biological processes to the precise nature of the salt present in solution. The term ‘ion-specific’ encompasses all the circumstances in which the influence of a salt in solution depends on the precise chemical nature of the salt, not just the electrical charge on the ions that form the salt. As such, ion-specific effects abound and have important consequences in most situations involving solutions, including cellular functions and battery technology. This project will enable us to understand and control the influence of specific ions, building on our recently described fundamental ion-specific series with colloid science experiments and quantum simulations. This project should overcome current challenges in predicting ion-specific effects leading to progress in a wide variety of applications of colloid and interface science, from sensor interfaces to self-assembly.Read moreRead less
Switchable and stereocontrolled photoredox catalysis. This project aims to develop new catalytic synthetic reactions for the rapid and more direct functionalisation of organic compounds under mild conditions with the use of visible light. An integrated experimental and computational approach will be used to design potent visible-light photocatalysts that retain the advantages of standard photoredox catalysis but with the added ability to intercept and, thus control, reactive intermediates in sit ....Switchable and stereocontrolled photoredox catalysis. This project aims to develop new catalytic synthetic reactions for the rapid and more direct functionalisation of organic compounds under mild conditions with the use of visible light. An integrated experimental and computational approach will be used to design potent visible-light photocatalysts that retain the advantages of standard photoredox catalysis but with the added ability to intercept and, thus control, reactive intermediates in situ. This will enable the control of stereochemistry in photoredox reactions – not possible with standard catalysts - and establish other useful synthetic transformations. These strategies will make it easier to prepare valuable classes of organic molecules – efficiently, safely, and cost-effectively.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100019
Funder
Australian Research Council
Funding Amount
$740,000.00
Summary
National Electron Beam Irradiation Facility. This project aims to address a gap for Australian researchers and start-ups by establishing a high energy electron beam facility. This project expects to generate new knowledge and manufacturing capacity in the areas of quantum sensing and quantum computing by enriching doped diamond and other wide band gap materials via controlled electron irradiation techniques. Expected outcomes include the creation of new quantum engineered materials and devices ....National Electron Beam Irradiation Facility. This project aims to address a gap for Australian researchers and start-ups by establishing a high energy electron beam facility. This project expects to generate new knowledge and manufacturing capacity in the areas of quantum sensing and quantum computing by enriching doped diamond and other wide band gap materials via controlled electron irradiation techniques. Expected outcomes include the creation of new quantum engineered materials and devices via an academic and industry collaborative effort. The proposed facility should provide significant benefits to Australian researchers and quantum start-ups through unrestricted access to a sovereign facility entirely dedicated to their needs, aiding training of the future quantum workforce.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101035
Funder
Australian Research Council
Funding Amount
$368,818.00
Summary
Gravitational wave detectors for observing the Cosmic Dawn. This project aims to build upon Australia’s already pioneering research into the workings of the universe by addressing challenges facing future gravitational wave detectors. It will develop and utilise advanced new numerical models to generate new knowledge on large-scale precision interferometry and contribute towards the design of future detectors that are essential for gravitational wave astronomy to thrive. Expected outcomes are ne ....Gravitational wave detectors for observing the Cosmic Dawn. This project aims to build upon Australia’s already pioneering research into the workings of the universe by addressing challenges facing future gravitational wave detectors. It will develop and utilise advanced new numerical models to generate new knowledge on large-scale precision interferometry and contribute towards the design of future detectors that are essential for gravitational wave astronomy to thrive. Expected outcomes are new optimised designs for detectors and an array of innovative new open-source numerical models for exploring new designs of quantum optics experiments. This will benefit both Australian and international research teams in the global effort to realise the third generation of gravitational wave detectors.Read moreRead less
Symmetry and geometric partial differential equations. This project aims to develop tools to assist the study of partial differential equations, which are fundamental to our understanding of the physical world. Symmetries of the Laplace equation are fundamental in both finding and interpreting its solutions and can be traced to the conformal symmetries of the underlying space. Only for the most symmetric of spaces, Euclidean space and the sphere, is this correspondence well understood. Using pow ....Symmetry and geometric partial differential equations. This project aims to develop tools to assist the study of partial differential equations, which are fundamental to our understanding of the physical world. Symmetries of the Laplace equation are fundamental in both finding and interpreting its solutions and can be traced to the conformal symmetries of the underlying space. Only for the most symmetric of spaces, Euclidean space and the sphere, is this correspondence well understood. Using powerful geometric tools from conformal geometry, the project will extend this to less symmetric spaces. The knowledge generated from this project will extend to more general geometric contexts providing a concrete setting for the study of the associated natural equations in curved spaces.Read moreRead less
ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reac ....ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reactions and how higher brain function emerges from networks of neurons. By building a diverse, multidisciplinary, and industry-engaged ecosystem, the Centre means to develop our future leaders at the interface of quantum science and biology and drive Australian innovation across manufacturing, energy, agriculture, health, and national security.Read moreRead less
New Horizons in Quinonedimethide Chemistry. Quinonedimethides (QDMs) are organic molecules with a notorious reputation for instability, hence they are poorly understood and an underexploited resource. This project will unite the ideally suited computational and experimental skills of the CIs to perform the first thorough investigation into fundamental QDM chemistry. It aims to map structure-reactivity in QDMs, investigate their ability to rapidly generate complex structures, and demonstrate thei ....New Horizons in Quinonedimethide Chemistry. Quinonedimethides (QDMs) are organic molecules with a notorious reputation for instability, hence they are poorly understood and an underexploited resource. This project will unite the ideally suited computational and experimental skills of the CIs to perform the first thorough investigation into fundamental QDM chemistry. It aims to map structure-reactivity in QDMs, investigate their ability to rapidly generate complex structures, and demonstrate their potential in spintronics and other applications. Anticipated outcomes include powerful and general new synthetic concepts, methods, strategies and tactics. This should provide significant benefits, such as better ways to manufacture important medicines and other materials.Read moreRead less
Metal-organic Framework (MOF) Superstructure Catalysts. The development of new catalyst technology is crucial to uncovering energy-efficient strategies for valorising chemicals. Although the designable pore networks of Metal-organic Frameworks (MOFs) provide a highly favourable environment for heterogeneous catalysis, most stable MOF materials are microporous - possessing pores less than 2 nm - which hinders mass transport. This research will develop novel, hierarchically porous MOF superstruct ....Metal-organic Framework (MOF) Superstructure Catalysts. The development of new catalyst technology is crucial to uncovering energy-efficient strategies for valorising chemicals. Although the designable pore networks of Metal-organic Frameworks (MOFs) provide a highly favourable environment for heterogeneous catalysis, most stable MOF materials are microporous - possessing pores less than 2 nm - which hinders mass transport. This research will develop novel, hierarchically porous MOF superstructures that will overcome these limitations and serve as platform materials for the development of new catalysts. This research will address future challenges in industrial catalysis and realise an important step towards the commercial application of MOF catalysis for valoriation of chemical feedstocks. Read moreRead less
Advancing the Chemistry of Metal-organic Frameworks for Biotechnology. This research will advance the fundamental chemical science required for the emerging field of Metal-organic Framework (MOF) biocomposites. A significant challenge to the commercial use of enzymes (biocatalysis), proteins (protein-based therapeutics) and virus-based vaccines is their instability to elevated temperatures and/or non-biological media. MOFs can encapsulate and protect biomolecules, thereby overcoming this limitat ....Advancing the Chemistry of Metal-organic Frameworks for Biotechnology. This research will advance the fundamental chemical science required for the emerging field of Metal-organic Framework (MOF) biocomposites. A significant challenge to the commercial use of enzymes (biocatalysis), proteins (protein-based therapeutics) and virus-based vaccines is their instability to elevated temperatures and/or non-biological media. MOFs can encapsulate and protect biomolecules, thereby overcoming this limitation. This project will develop fundamental parameters that govern the formation, stability and activity of these biocomposites, expanding the scope of MOF materials available for bioprotection, and enable new developments in the areas of industrial biocatalysis and protein/virus-based therapeutics.Read moreRead less