How Does Early Life Adversity “get Under The Skin” To Influence Lifelong Health? - Identifying Opportunities For Prevention Among Aboriginal And Ethnic Minority Peoples
Funder
National Health and Medical Research Council
Funding Amount
$425,048.00
Summary
This Fellowship will build upon my research to discover patterns and pathways of early life risk and resilience involved in long-term health outcomes for Aboriginal and ethnic minority children. This research will inform the planning of better targeted policy, public health and primary health care solutions for Aboriginal and ethnic minority children, families and communities in the critical early years of children’s lives.
Understanding The Regulation Of Cell Polarity In Development And Cancer
Funder
National Health and Medical Research Council
Funding Amount
$428,602.00
Summary
Cell polarity is the property of cells to be spatially oriented in a tissue or organ. We have now shown that the gene Scribble, a key regulator of cell orientation, may keep tumour development in check. In this proposal, we will examine how disruption of Scribble and associated molecules affects normal development and promotes cancer using a combination of tissue culture studies and a newly established mouse model. These studies may provide novel targets for therapeutic intervention in cancer.
Vestibulo-ocular Reflex Physiology, Pathology And Diagnosis.
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
A sensation of movement from the inner ear is used to stabilise vision during head movements. Without it, every time you walk, run, or drive on a bumpy road, the world would appear to bounce. It can be debilitating when this sense doesn't work due to various diseases. This research examines what causes these disorders and how the brain responds to help recovery. A diagnostic technique, that we will develop for wide clinical use, will be used to assess and identify treatments.