The study is the largest fracture care study will provide precise and accurate estimates of outcome in the early post injury period and enable determination of modifiable factors predicting major outcomes In NSW, the study results will identify limitations of the present compulsory third party (CTP) insurance scheme and help create a more efficient insurance scheme. This proposal involves an elite collaboration of researchers from Canada, Australia and South Asia.
Craig Anderson is a clinician-scientist, with specialist training in neurology and geriatrics, and an internationally-recognised epidemiologist and clinical trialist researcher. His work is dedicated to generating the highest quality evidence to improve the prevention and treatment of stroke and other neurological diseases related to ageing.
Environmental Risk Factors For Primary Progressive Multiple Sclerosis
Funder
National Health and Medical Research Council
Funding Amount
$86,118.00
Summary
Primary Progressive Multiple Sclerosis (PPMS) is a form of MS affecting 10% of people with the disease. PPMS has been less researched than the more common form of MS, Relapsing Remitting MS (RRMS), and unlike RRMS, there are currently no effective treatments. This project will examine whether the established risk factors for RRMS also hold for PPMS, whether the magnitude of risk associated with these factors is the same for PPMS, and whether novel risk factors for PPMS can be identified.
Do Exposures Before Conception Influence The Risk Of Asthma In Offspring?
Funder
National Health and Medical Research Council
Funding Amount
$688,586.00
Summary
Asthma and poor lung function are major causes of public health issues. Emerging evidence suggests adverse exposures even before the conception of a child may cause these conditions. The proposed project is part of an international study across generations to identify these factors. This study will provide novel evidence to guide interventions and identify studies to advance this area further. These original findings will be of great importance both nationally and internationally.
Environmental Risk Factors And Genetic Modifiers For Lung Health And Lung Function In A High Risk Cohort
Funder
National Health and Medical Research Council
Funding Amount
$95,348.00
Summary
Asthma is an important determinant of respiratory health and longevity. While early life exposures are thought to be important, the evidence linking them with asthma and lung function is inconclusive. There is a scarcity of longitudinal studies and few investigate genes and environment. This study will determine whether environmental exposures along with their relevant genetic modifiers are related to increased risk of asthma and impaired lung function in a high allergy risk birth cohort.
The Predictors Of Asthma And Lung Function Deficits In The Third Decade: Longitudinal Study Of MACS Sibships
Funder
National Health and Medical Research Council
Funding Amount
$1,176,908.00
Summary
This will be the world’s first birth cohort study to use substantial prospective data to investigate how biological, psychosocial, and environmental markers from birth will predict asthma and lung function in the third decade of life. Our findings will be crucial to the development of new policy and practice for the prevention and management of these conditions and uncover crucial risk factors for young adult asthma.
Defining An Ethical And Evidence-based Approach To Clinical Research In Children And Adolescents With Chronic Kidney Disease (CKD)
Funder
National Health and Medical Research Council
Funding Amount
$84,800.00
Summary
Chronic kidney disease (CKD) in children and adolescents is a serious health condition, which impacts patients' academic abilities and achievement as well as their social wellbeing and their physical and mental health. This study will investigate the range of impacts that CKD has on patients and families, and explore the ways that these problems should best be addressed in future research from the perspective of patients and their families.
The Second Australian Study Of Health And Relationships
Funder
National Health and Medical Research Council
Funding Amount
$1,637,477.00
Summary
The present proposal is for the Second Australian Study of Health and Relationships, a survey of 20,000 Australians aged 16–69, in 2011–12 in order to understand and document the changes in Australian sexual behaviour over the past decade. It is essential that policy and practice in the arena of sexual and reproductive health be evidence-based and that the evidence base be as current as is practicable.