Linking Genomics Of Burkholderia Pseudomallei To Melioidosis: Diversity Of Clinical Manifestations, Changing Epidemiology And Microevolution In Chronic Carriage.
Funder
National Health and Medical Research Council
Funding Amount
$602,769.00
Summary
The Darwin Prospective Melioidosis Study has documented 761 cases since 1989, with 102 fatalities. This study has led to improved therapy and public health initiatives. New technology to sequence whole bacterial genomes provides an opportunity to determine why urban melioidosis is increasing and to analyse this unique 22+ year set of bacteria and their linked patient data to find the important bacterial virulence factors, forming a foundation for future diagnostics, therapeutics, and vaccines.
Improving Sub-national Population Forecasts. The aim of this project is to make significant advances in two related areas of regional, council area and local population forecasting, namely improving accuracy, and providing an indication of forecast uncertainty. Population forecasts often turn out to be far more inaccurate than users realise and fail to come with any information about reliability. Every year forecasts inform a wide variety of planning and policy development activities and influen ....Improving Sub-national Population Forecasts. The aim of this project is to make significant advances in two related areas of regional, council area and local population forecasting, namely improving accuracy, and providing an indication of forecast uncertainty. Population forecasts often turn out to be far more inaccurate than users realise and fail to come with any information about reliability. Every year forecasts inform a wide variety of planning and policy development activities and influence investment decisions worth billions of dollars. In order to increase the value of forecasts to users, this project aims to combine methods from a range of disciplines to devise more accurate ways of forecasting populations, and provide accompanying information on their likely error.Read moreRead less
Gambling-related harm in Northern Australia: A Geographic Information Systems (GIS)-based spatiotemporal analysis of venue catchments. There is growing national concern about the impact of electronic gaming (poker) machines yet little is known about the effects of this gambling in rural and remote areas of Australia. We will develop a database to define the geographic distribution of gambling impacts, the nature of high-risk venues, and the characteristics, both spatial and social, of vulnerable ....Gambling-related harm in Northern Australia: A Geographic Information Systems (GIS)-based spatiotemporal analysis of venue catchments. There is growing national concern about the impact of electronic gaming (poker) machines yet little is known about the effects of this gambling in rural and remote areas of Australia. We will develop a database to define the geographic distribution of gambling impacts, the nature of high-risk venues, and the characteristics, both spatial and social, of vulnerable communities. This will enable the design of much needed harm minimisation strategies and will provide regulatory bodies with insights into the capacity of local communities to absorb the impact of electronic gaming machine venues.Read moreRead less
Planning for sustainable development and biodiversity on Indigenous lands. This project aims to develop a new approach to participatory land-use planning for sustainable development and conservation, in partnership with the Tiwi Land Council. Planning for sustainable development is complex but vital to reconciling economic, social and conservation goals worldwide. The project will evaluate land-use scenarios, including Indigenous Protected Areas, with ecological and economic models that integrat ....Planning for sustainable development and biodiversity on Indigenous lands. This project aims to develop a new approach to participatory land-use planning for sustainable development and conservation, in partnership with the Tiwi Land Council. Planning for sustainable development is complex but vital to reconciling economic, social and conservation goals worldwide. The project will evaluate land-use scenarios, including Indigenous Protected Areas, with ecological and economic models that integrate Indigenous and scientific knowledge. Benefits will include new planning tools and improved understanding of trade-offs between goals, especially on Australia’s Indigenous estates.Read moreRead less
Securing the essential: assisting Indigenous communities and their service providers to sustainably manage water and energy supply. The provision of water and energy supplies to remote Aboriginal and Torres Strait Islander (ATSI) communities is a critical challenge for service providers. This project uses a novel unobtrusive smart metering system, aligned with culturally appropriate consultation with ATSI communities, to reveal patterns of household water and water related-energy consumption. Si ....Securing the essential: assisting Indigenous communities and their service providers to sustainably manage water and energy supply. The provision of water and energy supplies to remote Aboriginal and Torres Strait Islander (ATSI) communities is a critical challenge for service providers. This project uses a novel unobtrusive smart metering system, aligned with culturally appropriate consultation with ATSI communities, to reveal patterns of household water and water related-energy consumption. Significantly, the research aims to identify effective behavioural and technological water and energy efficiency strategies in three remote ATSI communities in Queensland, Northern Territory and Western Australia. A key outcome is to provide an adaptive evidence-based and community-driven handbook to facilitate the secure long-term supply and efficient use of energy and water resources in remote ATSI communities.Read moreRead less
CENTRE OF RESEARCH EXCELLENCE TO REDUCE INEQUALITY IN HEART DISEASE
Funder
National Health and Medical Research Council
Funding Amount
$2,607,253.00
Summary
There is increasing recognition of a societal responsibility to provide effective and sustainable health care to the entire population and not just to selected parts. Indigenous and regional Australians are most affected by Australia's biggest killer - heart disease. In response, the CRE to Reduce Inequality in Heart Disease, is a national collaboration of researchers from a range of health disciplines. Together they aim to address this problem by developing sustainable and cost-effective health ....There is increasing recognition of a societal responsibility to provide effective and sustainable health care to the entire population and not just to selected parts. Indigenous and regional Australians are most affected by Australia's biggest killer - heart disease. In response, the CRE to Reduce Inequality in Heart Disease, is a national collaboration of researchers from a range of health disciplines. Together they aim to address this problem by developing sustainable and cost-effective health care services.Read moreRead less
Cane toads in southern Australia: invasion dynamics and options for control. This project aims to investigate the spread of cane toads through southern Australia, an invasion front that has attracted far less research than the same species’ expansion through tropical regions, even though toads severely impact native wildlife in both areas. This project expects to generate new knowledge to determine why the rate of toad invasion is so much slower in New South Wales than in the tropics, and how be ....Cane toads in southern Australia: invasion dynamics and options for control. This project aims to investigate the spread of cane toads through southern Australia, an invasion front that has attracted far less research than the same species’ expansion through tropical regions, even though toads severely impact native wildlife in both areas. This project expects to generate new knowledge to determine why the rate of toad invasion is so much slower in New South Wales than in the tropics, and how best to modify newly-developed approaches to toad control to the conditions in southern Australia. Expected outcomes include predicting future trajectories of expansion, and identifying optimal approaches to toad control and impact mitigation. This should provide significant benefits for biodiversity conservation.Read moreRead less
Call Out and Listen In: A New Way to Detect and Control Invasive Species. This project aims to use novel acoustic techniques to detect and capture invasive frog species to protect native species. Invasive frogs are an under-appreciated but serious ecological problem worldwide, because they are voracious predators and are often toxic to native species. Male frogs call to attract mates, and answer calls they hear. Using new acoustic technologies, these behaviours can be exploited to detect species ....Call Out and Listen In: A New Way to Detect and Control Invasive Species. This project aims to use novel acoustic techniques to detect and capture invasive frog species to protect native species. Invasive frogs are an under-appreciated but serious ecological problem worldwide, because they are voracious predators and are often toxic to native species. Male frogs call to attract mates, and answer calls they hear. Using new acoustic technologies, these behaviours can be exploited to detect species and attract gravid females for removal. This project aims to combine an early warning system (electronic listening) and trap (calling and catching), which can be customised to any invasive frog, and use it to detect and remove cane toads, especially in low density populations.Read moreRead less
Either side of the Big Wet: the future resilience of south-eastern Australia's biota. Australia must develop strategies for managing its biodiversity under climate changes expected to occur under projected Intergovernmental Panel on Climate Change (IPCC) emission scenarios. The project will furnish comprehensive data on the response of plants and animals to the break in the Big Dry (1997-2009) in 2010-11 and evaluate how predict biotic components will cope with future climates.
Transforming Cultural & Natural Resource Management workforce capabilities. This project aims to implement a transformative program of transdisciplinary cultural and natural resource management and workforce development research in Northern Australia’s Arnhem Plateau region. This project expects to create new knowledge in the areas of cultural knowledges, wildfire, feral animal, invasive plants, mine-site rehabilitation, and climate change, as well as Indigenous training effectiveness. Expected ....Transforming Cultural & Natural Resource Management workforce capabilities. This project aims to implement a transformative program of transdisciplinary cultural and natural resource management and workforce development research in Northern Australia’s Arnhem Plateau region. This project expects to create new knowledge in the areas of cultural knowledges, wildfire, feral animal, invasive plants, mine-site rehabilitation, and climate change, as well as Indigenous training effectiveness. Expected outcomes of the project include practical learnings for application in broader Indigenous community/First Nations capability and supportive policy development contexts. The expected benefits are a long-term platform for enhancing cultural and environmental landscape management and sustainable employment opportunities.Read moreRead less