Harnessing Neuroplasticity To Improve Motor Performance In Infants With Cerebral Palsy: A Pragmatic Randomized Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,736,349.00
Summary
Every 15 hours an Australian baby is born with cerebral palsy. Despite confidence in early intervention, 50% don't receive intervention before their first birthday while awaiting diagnosis, and 8 of 10 previous trials have not produced any physical gains over and above natural development. We have promising data about a new brain training intervention that harnesses neuroplasticity and improves movement. Our trial will treat 300 infants with early training comparing results to Standard Care.
Home-based Speech Treatment For Parkinsons Disease Via Telerehabilitation : Clinical And Economic Outcomes.
Funder
National Health and Medical Research Council
Funding Amount
$485,793.00
Summary
Parkinson's Disease affects a person's ability to speak clearly. Speech pathologists can provide effective treatment for this speech disorder. Access to a speech pathologist, however, is difficult for many people with Parkinson's Disease due to their physical difficulties and the limited availability of speech pathology services in rural areas. This study demonstrates the use of telerehabilitation to deliver speech treatment to people with Parkinson's Disease in their own homes via the Internet.
Developing a framework for effective oyster reef restoration. This project aims to investigate ecological barriers to the recovery of functionally extinct Sydney Rock Oyster reefs on Australia’s east coast, and restoration methods to reinstate their key ecosystem services. This project expects to create new knowledge for designing functional reefs by integrating physiology, population, community and landscape ecology. Expected outcomes are an ecological decision framework for effective oyster re ....Developing a framework for effective oyster reef restoration. This project aims to investigate ecological barriers to the recovery of functionally extinct Sydney Rock Oyster reefs on Australia’s east coast, and restoration methods to reinstate their key ecosystem services. This project expects to create new knowledge for designing functional reefs by integrating physiology, population, community and landscape ecology. Expected outcomes are an ecological decision framework for effective oyster reef restoration that can be integrated into management and policy. This project should provide significant benefits, such as the development of key strategic alliances to enhance management of estuaries, and reestablish the environmental, economic and social benefits of oyster reefs.Read moreRead less
Spinal complaints present the greatest social and economic burden of musculoskeletal conditions in Australia. This reflects current realities: the cause remains unknown; 80% of the population is affected; and isolated professions perform a staggering array of interventions. The CCRE aims to target these realities and improve Australia's capacity to prevent and manage spinal disorders by supporting innovative interdisciplinary research and training. This community- and university-based centre wil ....Spinal complaints present the greatest social and economic burden of musculoskeletal conditions in Australia. This reflects current realities: the cause remains unknown; 80% of the population is affected; and isolated professions perform a staggering array of interventions. The CCRE aims to target these realities and improve Australia's capacity to prevent and manage spinal disorders by supporting innovative interdisciplinary research and training. This community- and university-based centre will align highly successful clinical and basic researchers in collaboration with a national network of spine scientists to foster interdisciplinary clinical researcher training, develop new diagnostics and therapeutics, and translate findings to the community. Through clinical research the centre aims to: (i) Advance understanding of physiology and pathophysiology of spinal pain (ii) Translate findings from basic research to clinical practice (iii) Establish coordinated multidisciplinary research to reduce the burden of spinal pain (iv) Predict and prevent the transition from acute to chronic states (v) Train a new generation of transdisciplinary clinical scientists (vi) Rapidly assess new treatment possibilities in pre-clinical studies (vii) Develop innovative technologies for diagnostics and therapeutics (viii) Encourage Australian commercialisation opportunities for new discoveries (ix) Encourage community-user participation in direction of research programs (x) Disseminate new findings and information of evidence-based practice to patients, clinicians, insurers, government and the scientific and wider communityRead moreRead less
Ecosystem restoration of bauxite-processing residue sand disposal areas in Western Australia: Important biogeochemical processes and effective fertilisation strategies. Alumina production is one of Australia's most important mining activities. Residue from bauxite-processing must be managed appropriately to minimise detrimental impacts on the surrounding environment. The location of Alcoa's WA Refineries in environmentally- and community- sensitive areas necessitates a detailed understanding of ....Ecosystem restoration of bauxite-processing residue sand disposal areas in Western Australia: Important biogeochemical processes and effective fertilisation strategies. Alumina production is one of Australia's most important mining activities. Residue from bauxite-processing must be managed appropriately to minimise detrimental impacts on the surrounding environment. The location of Alcoa's WA Refineries in environmentally- and community- sensitive areas necessitates a detailed understanding of residue disposal area (RDA) management. Currently little is known about the biogeochemical cycling of nitrogen, phosphorus and carbon in the residue sand despite its importance for sustainable rehabilitation practice. Findings from this project are critical for developing improved fertilisation strategies and protocols for ecosystem restoration of RDAs, which will be applicable both in Australia and overseas. Read moreRead less
Mid-Career Industry Fellowships - Grant ID: IM230100184
Funder
Australian Research Council
Funding Amount
$1,034,832.00
Summary
A new catchment gully erosion model for a healthier Great Barrier Reef . Sediment impacts Great Barrier Reef water quality and coral health. Erosion of gullies within a river catchment are the dominant source of sediment. This project aims to develop a novel catchment level modelling tool, allowing land managers to compare rehabilitation options and identify optimal actions. The project will generate new knowledge in applied mathematics, using innovative model emulation techniques to bring proce ....A new catchment gully erosion model for a healthier Great Barrier Reef . Sediment impacts Great Barrier Reef water quality and coral health. Erosion of gullies within a river catchment are the dominant source of sediment. This project aims to develop a novel catchment level modelling tool, allowing land managers to compare rehabilitation options and identify optimal actions. The project will generate new knowledge in applied mathematics, using innovative model emulation techniques to bring process insights to the catchment scale. Expected outcomes include a validated land rehabilitation decision making tool, benefiting both natural resource managers by increasing ability to meet Reef 2050 policy targets and landowners though development of Natural Capital Markets.Read moreRead less
Optimising seed sourcing for effective ecological restoration. This project aims to address the sourcing of native seed for ecological restoration under global change. The great demand for native seed to deliver ecological restoration provides a clear need and responsibility to use this seed as efficiently as possible. This project expects to develop detailed new knowledge that links plant and environmental genomics, plant physiology, seed and soil biology in embedded experiments at post-mining ....Optimising seed sourcing for effective ecological restoration. This project aims to address the sourcing of native seed for ecological restoration under global change. The great demand for native seed to deliver ecological restoration provides a clear need and responsibility to use this seed as efficiently as possible. This project expects to develop detailed new knowledge that links plant and environmental genomics, plant physiology, seed and soil biology in embedded experiments at post-mining rehabilitation sites. Expected outcomes include clear industry guidelines that refine seed sourcing strategies for ecological restoration for current and future climates. This should provide significant benefits for improved ecological restoration outcomes when using native seed today and into the future.Read moreRead less
Optimising the spring in your step to enhance footwear design. This project aims to examine how the nervous system adjusts the mechanical function of our feet across a spectrum of speeds, from slow running through to maximal effort sprinting. The proposed research will explore how the nervous system controls the function of the foot to meet the ever-varying demands of locomotion in the real-world. Expected outcomes of this project are to determine if running shoes help or hinder the natural spri ....Optimising the spring in your step to enhance footwear design. This project aims to examine how the nervous system adjusts the mechanical function of our feet across a spectrum of speeds, from slow running through to maximal effort sprinting. The proposed research will explore how the nervous system controls the function of the foot to meet the ever-varying demands of locomotion in the real-world. Expected outcomes of this project are to determine if running shoes help or hinder the natural spring-like function of the foot. It will explain a conceptually novel design allowing shoes to support our feet, whilst harnessing the energetic benefits of the foot's spring-like function. This research has the potential to revolutionise athletic footwear design and has direct implications for enhanced performance in running athletes.Read moreRead less
Intervention ecology on coral reefs: a new role for fishes. In a world where few intact reefs remain, the goal of this project is to find ways to restore degraded reefs. Recent research has identified the species responsible for removing harmful algae from coral reefs, while advances in mariculture provide us with the capacity to rear these critically important reef fish species. Combining captive rearing, experimental manipulations, and a global analysis of the functional capacity of herbivorou ....Intervention ecology on coral reefs: a new role for fishes. In a world where few intact reefs remain, the goal of this project is to find ways to restore degraded reefs. Recent research has identified the species responsible for removing harmful algae from coral reefs, while advances in mariculture provide us with the capacity to rear these critically important reef fish species. Combining captive rearing, experimental manipulations, and a global analysis of the functional capacity of herbivorous fishes, in intact, degraded and human-modified systems, the research will explore the potential for restoring, or boosting, the capacity of reefs to withstand disturbance. The goal is to provide the scientific knowledge required to directly modify the key processes operating on coral reefs. Read moreRead less
Spatial scale of influence of riparian and catchment land use on stream ecosystem health. Human activities at the landscape scale comprise one of the greatest threats to the ecological integrity of river ecosystems. Government and community groups across Australia are making significant efforts in riparian protection and rehabilitation in an attempt to improve the health of degraded waterways but are hampered in their goal to maximise the environmental gains for every dollar or unit effort inve ....Spatial scale of influence of riparian and catchment land use on stream ecosystem health. Human activities at the landscape scale comprise one of the greatest threats to the ecological integrity of river ecosystems. Government and community groups across Australia are making significant efforts in riparian protection and rehabilitation in an attempt to improve the health of degraded waterways but are hampered in their goal to maximise the environmental gains for every dollar or unit effort invested. The proposed research on understanding the spatial scale of influence of land use and the aggregative effects on stream ecosystems will provide a robust framework to assess various options and optimise benefits from management actions. Read moreRead less