Enabling Personalised Risk Assessment For Colorectal Cancer
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
Bowel cancer screening will be most effective in disease prevention if it is applied proportionately to individual person's risk. Risk-based screening requires a risk calculator to assess personal risk. By utilising existing large, international datasets, I will identify the risk factors specific for different bowel cancer types and incorporate them to upgrade the prediction model that I have developed. This will achieve more accurate risk prediction to enable personalised risk-based screening.
Seeing Change: Science, Culture and Technology in the Antipodes from the age of Darwin - a multi-media research collaboration. To build a collaboration across the humanities, natural sciences, business technology and public culture sectors that will use new forms of digital and visual research to demonstrate the neglected importance of Australasia in the formation of nineteenth-century evolutionary thought and to suggest the relevance of these ideas to understanding contemporary issues of enviro ....Seeing Change: Science, Culture and Technology in the Antipodes from the age of Darwin - a multi-media research collaboration. To build a collaboration across the humanities, natural sciences, business technology and public culture sectors that will use new forms of digital and visual research to demonstrate the neglected importance of Australasia in the formation of nineteenth-century evolutionary thought and to suggest the relevance of these ideas to understanding contemporary issues of environmental sustainability and the development of frontier technologies within our society and region. Read moreRead less
Special Research Initiatives - Grant ID: SR0567393
Funder
Australian Research Council
Funding Amount
$100,000.00
Summary
Infrastructure for large-scale data resource sharing between research institutions – an environmental case study. The project creates a federated distributed data infrastructure for research, that encourages data creators to make their data available to other scientists, and encourages users to make use of data available from many sources. The vision is to establish an ICT infrastructure to facilitate a whole-of-environment approach to environmental research. The outcome is a proof-of-concept ....Infrastructure for large-scale data resource sharing between research institutions – an environmental case study. The project creates a federated distributed data infrastructure for research, that encourages data creators to make their data available to other scientists, and encourages users to make use of data available from many sources. The vision is to establish an ICT infrastructure to facilitate a whole-of-environment approach to environmental research. The outcome is a proof-of-concept application based upon a case study of Queensland Environmental Protection Agency’s databases, to gain an in-depth understanding of the complexity, scope and key technological barriers for establishing an ICT infrastructure, to identify where the latest technologies can be used and where the gaps are for these technologies to be used in environmental sciences.Read moreRead less
Social acceptability of forest management options: Landscape level visualisation and evaluation. Sustainable forest policy requires social acceptance. Prior research has investigated relative acceptability of options at a forest stand level. However, we have insufficient understanding of public acceptance of forest management systems implemented across the wider landscape. Only detailed knowledge of public reaction to social, environmental and economic impacts and the trade-offs involved can red ....Social acceptability of forest management options: Landscape level visualisation and evaluation. Sustainable forest policy requires social acceptance. Prior research has investigated relative acceptability of options at a forest stand level. However, we have insufficient understanding of public acceptance of forest management systems implemented across the wider landscape. Only detailed knowledge of public reaction to social, environmental and economic impacts and the trade-offs involved can reduce the divisive nature of the forest management debate. This project will use interactive, still and animated computer representations of landscapes to examine social acceptability of alternatives to clearfell harvesting. This knowledge will be integrated with biophysical data to improve management of forested landscapes.Read moreRead less
Acceptability of Forest Harvesting Systems. Fierce public debate over forest management has prompted forest agencies to develop and test alternative harvesting systems. This project will examine community response to these harvesting and regeneration options. It will avoid the biases of existing research by developing an interactive simulation of the forest environment that will allow participants to view visual, ecological and economic outcomes of harvest options, as well as changes over time ....Acceptability of Forest Harvesting Systems. Fierce public debate over forest management has prompted forest agencies to develop and test alternative harvesting systems. This project will examine community response to these harvesting and regeneration options. It will avoid the biases of existing research by developing an interactive simulation of the forest environment that will allow participants to view visual, ecological and economic outcomes of harvest options, as well as changes over time as forest regenerates. Public judgements of the acceptability of harvesting options will be integrated with the outcomes of related biophysical studies to identify socially and ecologically sustainable management options for Australian native forests.Read moreRead less
Modelling Of Clinic And Ambulatory Blood Pressure On Cardiovascular Risk And Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$133,957.00
Summary
Whilst ambulatory blood pressure monitoring data has been shown to be a good predictor of cardiovascular events, there remains controversy as to its utility in clinical practice. This project will use data from existing population and clinical cohort studies to examine the role of ambulatory blood pressure in risk assessment and hypertension management in Australia and around the globe. The findings are likely to have a major impact on clinical guidelines for hypertension management.
Young Onset Colorectal Cancer: Genetics Pathology And Environment
Funder
National Health and Medical Research Council
Funding Amount
$439,180.00
Summary
There has been a steady increase since 2002, in the age-standardised incidence of CRC in males under 45 years in Australia, contrasting with the stabilisation in incidence of CRC in males of age 45 years and over. Persons under 50 years are not routinely screened unless they have a significant family history of CRC. Young-onset rectal cancer is associated with late presentations and with a higher mortality. This proposal will address the possible risk factors for young-onset CRC.
A Unified Grid Programming Methodology for Global e-Science. This project will contribute to the national benefit in three important ways. First, we will build a set of novel e-Science applications as demonstrator projects in areas of national priority. These will have enormous economic impact in areas ranging from environmental management to health. Second, we will build software infrastructure that will have both commercial and strategic value in its own right. Third, we shall build a critical ....A Unified Grid Programming Methodology for Global e-Science. This project will contribute to the national benefit in three important ways. First, we will build a set of novel e-Science applications as demonstrator projects in areas of national priority. These will have enormous economic impact in areas ranging from environmental management to health. Second, we will build software infrastructure that will have both commercial and strategic value in its own right. Third, we shall build a critical mass of expertise that bridges the physical sciences and computer science. The support provided to this proposal will allow multi-disciplinary teams to address scientific problems of significant scale.Read moreRead less
Tuning parallel applications on software-defined supercomputers. Supercomputers are used by many Australian industries and laboratories to make better products and perform critical predictions, and it is essential that codes operate efficiently. This project aims to assist programmers in identifying performance bottlenecks in their code quickly and easily. The project expects to supersede the current methods, which are often complex and time-consuming, by developing innovative software tools and ....Tuning parallel applications on software-defined supercomputers. Supercomputers are used by many Australian industries and laboratories to make better products and perform critical predictions, and it is essential that codes operate efficiently. This project aims to assist programmers in identifying performance bottlenecks in their code quickly and easily. The project expects to supersede the current methods, which are often complex and time-consuming, by developing innovative software tools and techniques. The expected outcomes include novel software, verified by industry partners in real world case studies, ranging from life sciences to hypersonic transport. This should provide significant benefits, including the capacity for Australian industries to access world-class supercomputing technology.Read moreRead less
Large-Scale Emulation for Enterprise Software Systems. This project will deliver a key future software technology for scalable quality assurance of highly interconnected enterprise IT systems, significantly contributing to more reliable and effective business operations in all industry sectors. It will fill a market gap and give Australian businesses a world competitive advantage. The project will generate world-leading research outcomes and further cement Australia’s leading research position i ....Large-Scale Emulation for Enterprise Software Systems. This project will deliver a key future software technology for scalable quality assurance of highly interconnected enterprise IT systems, significantly contributing to more reliable and effective business operations in all industry sectors. It will fill a market gap and give Australian businesses a world competitive advantage. The project will generate world-leading research outcomes and further cement Australia’s leading research position in enterprise software systems engineering. In particular, it will make major contributions to research into complex large-scale system interaction, system performance and scalability, and system behaviour modelling. The project also provides an excellent training environment for young researchers. Read moreRead less