Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
The contribution of human/marine herbivore interactions to reef degradation. This project aims to define how interactions between human society and herbivores influence marine ecosystem structure and function. It will analyse geographic patterns from recent systematic sampling of reef communities worldwide and study fish, macro-invertebrate and meso-grazer herbivory to identify herbivores’ role in the collapse and recovery of reef ecosystems. This project will examine the match between a critica ....The contribution of human/marine herbivore interactions to reef degradation. This project aims to define how interactions between human society and herbivores influence marine ecosystem structure and function. It will analyse geographic patterns from recent systematic sampling of reef communities worldwide and study fish, macro-invertebrate and meso-grazer herbivory to identify herbivores’ role in the collapse and recovery of reef ecosystems. This project will examine the match between a critical ecosystem function and community structure across local to global scales, including the identification of non-linearities and interactions involving human effects on this process. This research is expected to safeguard marine ecosystems from collapse.Read moreRead less
Putting death in its place. The project aims to link 890,000 population records to place of residence from 1838 to 1930, to examine the relationships between where people live, mortality, life expectancy and health. Where people live impacts their life-course outcomes. Using novel matching techniques, the project expects to identify intergenerational changes and the spatial dynamics of inequality and social mobility. Expected outcomes include the creation of a public resource of linked data and ....Putting death in its place. The project aims to link 890,000 population records to place of residence from 1838 to 1930, to examine the relationships between where people live, mortality, life expectancy and health. Where people live impacts their life-course outcomes. Using novel matching techniques, the project expects to identify intergenerational changes and the spatial dynamics of inequality and social mobility. Expected outcomes include the creation of a public resource of linked data and a better understanding of long-run health and inequality. These should provide economic and social benefits by informing policy aimed at contemporary social and health challenges, enhancing our understanding of Australian history, and developing public resources.Read moreRead less
Developing feasible in situ control of mange disease in wombats. Our goal is the development of feasible in situ control of sarcoptic mange in wombat populations. Globally important, the Sarcoptes scabiei mite infects >100 mammal species and is among the 50 most common human diseases, causing health, welfare and population impacts. This infection is treatable, and we will test a new treatment (fluralaner), develop new models to guide management, and conduct replicated field trials. This will ena ....Developing feasible in situ control of mange disease in wombats. Our goal is the development of feasible in situ control of sarcoptic mange in wombat populations. Globally important, the Sarcoptes scabiei mite infects >100 mammal species and is among the 50 most common human diseases, causing health, welfare and population impacts. This infection is treatable, and we will test a new treatment (fluralaner), develop new models to guide management, and conduct replicated field trials. This will enable science-based guidelines, advancing disease control, local eradication, and regulatory approval for wombats. Our research framework is adaptable to other mange-impacted species, and advance methods and theory for control of treatable disease in wildlife.Read moreRead less
Development of an immunology toolbox to combat emerging marsupial diseases. Disease is increasingly a driver of wildlife population declines in Australia. However, basic immunology tools for >99% of vertebrate species are scarce, limiting our ability to prevent and respond to emerging and endemic diseases, such as devil facial tumour disease and wobbly possum disease. The overarching goal of this project is to improve wildlife health and fill the marsupial immunology gap by developing a long-ove ....Development of an immunology toolbox to combat emerging marsupial diseases. Disease is increasingly a driver of wildlife population declines in Australia. However, basic immunology tools for >99% of vertebrate species are scarce, limiting our ability to prevent and respond to emerging and endemic diseases, such as devil facial tumour disease and wobbly possum disease. The overarching goal of this project is to improve wildlife health and fill the marsupial immunology gap by developing a long-overdue multispecies marsupial immunology toolbox. The toolbox is needed to accelerate devil facial tumour disease vaccine progress and conservation immunology research. It will expand our knowledge of wobbly possum disease virus that is increasingly reported in Tasmania and the risk posed by the virus to other possum species.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100028
Funder
Australian Research Council
Funding Amount
$3,000,000.00
Summary
Australian Membership of the International Ocean Discovery Program. This proposal is for an 18-month membership of the International Ocean Discovery Program (IODP), the world’s largest collaborative research program in Earth and Ocean sciences. The Program studies the history and current activity of the Earth by conducting seagoing coring expeditions and monitoring of instrumented boreholes, using globally unique infrastructure that Australians would otherwise have no access to. Program outcomes ....Australian Membership of the International Ocean Discovery Program. This proposal is for an 18-month membership of the International Ocean Discovery Program (IODP), the world’s largest collaborative research program in Earth and Ocean sciences. The Program studies the history and current activity of the Earth by conducting seagoing coring expeditions and monitoring of instrumented boreholes, using globally unique infrastructure that Australians would otherwise have no access to. Program outcomes include understanding past global environmental change on multiple time scales, the deep biosphere, plate tectonics, formation and distribution of resources, and generation of hazards. These outcomes are paramount to Australia’s national science and research priorities, and societal and economic prosperity.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH220100012
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Carbon Utilisation and Recycling. This Research Hub aims to develop technologies to transform carbon dioxide emissions from our energy and manufacturing sectors into valuable products and create pathways to market to drive industry transformation. This hub aims to achieve this by developing novel electro, thermo, and biochemical methods for converting CO2 from sectors that cannot easily avoid emissions and a technological pathway for CO2 recycling. The outcomes of this Hub a ....ARC Research Hub for Carbon Utilisation and Recycling. This Research Hub aims to develop technologies to transform carbon dioxide emissions from our energy and manufacturing sectors into valuable products and create pathways to market to drive industry transformation. This hub aims to achieve this by developing novel electro, thermo, and biochemical methods for converting CO2 from sectors that cannot easily avoid emissions and a technological pathway for CO2 recycling. The outcomes of this Hub are likely to be transformative for industry, the economy, and society in moving the fate of CO2 from pollutant to feedstock. The benefits to Australia are intended to be the stimulation of a new industry, a skilled workforce for this emerging industry and a contribution to meeting CO2 reduction targets.Read moreRead less
Seafood safety: high throughput diagnostics for ciguatoxin risk assessment. This project aims to develop a novel, high throughput platform for rapidly assessing ciguatoxins. Species of the marine microalgae Gambierdiscus produce ciguatoxins, which accumulate in fish through marine food chains to cause the often debilitating human illness called ciguatera fish poisoning. Ciiguatera fish poisoning is a growing and substantial risk for the $2.2 billion Australian commercial fishing industry. This s ....Seafood safety: high throughput diagnostics for ciguatoxin risk assessment. This project aims to develop a novel, high throughput platform for rapidly assessing ciguatoxins. Species of the marine microalgae Gambierdiscus produce ciguatoxins, which accumulate in fish through marine food chains to cause the often debilitating human illness called ciguatera fish poisoning. Ciiguatera fish poisoning is a growing and substantial risk for the $2.2 billion Australian commercial fishing industry. This serious illness is increasingly impacting more southerly areas of Australia due to environmental changes. The outcomes of this project include new knowledge of the risk of ciguatoxins at Australian 'hot spot' sites, extensively field tested methods for detecting Gambierdiscus and ciguatoxins in situ and key data to inform policy to safeguard the seafood industry and consumers.
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ARC Centre of Excellence for Australian Biodiversity and Heritage. The ARC Centre of Excellence of Australian Biodiversity and Heritage will create a world-class interdisciplinary research programme to understand Australia’s unique biodiversity and heritage. The Centre will track the changes to Australia’s environment to examine the processes responsible for the changes and the lessons that can be used to continue to adapt to Australia’s changing environment. The Centre will support connection ....ARC Centre of Excellence for Australian Biodiversity and Heritage. The ARC Centre of Excellence of Australian Biodiversity and Heritage will create a world-class interdisciplinary research programme to understand Australia’s unique biodiversity and heritage. The Centre will track the changes to Australia’s environment to examine the processes responsible for the changes and the lessons that can be used to continue to adapt to Australia’s changing environment. The Centre will support connections between the sciences and humanities and train future generations of researchers to deal with future global challenges and inform policy in an interdisciplinary context. Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100022
Funder
Australian Research Council
Funding Amount
$4,787,259.00
Summary
ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop pr ....ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop protection. An expert multidisciplinary team uniting science, commercial and social licence pathways ensures industry and consumer uptake advancing $60B Australian Agriculture. The Hub translates to increased productivity, market access and enhanced environmental credentials of Australian food.
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