Accurate Location Service for 3G Cellular Networks. The project aims to improve the accuracy of automatic location identification of GPS enabled handsets in third-generation cellular networks via a modified Differential GPS method. The proposed sub-metre location ability will be a value-added service of the network providers and will appeal to a wide sector of users. The challenge is to develop a cost effective solution by utilising existing network infrastructure. We propose to use the GPS timi ....Accurate Location Service for 3G Cellular Networks. The project aims to improve the accuracy of automatic location identification of GPS enabled handsets in third-generation cellular networks via a modified Differential GPS method. The proposed sub-metre location ability will be a value-added service of the network providers and will appeal to a wide sector of users. The challenge is to develop a cost effective solution by utilising existing network infrastructure. We propose to use the GPS timing units in 3G networks for deriving local GPS position corrections; and to transfer these corrections to the users via the 3G data bursts of the beacons or other user data broadcasts.Read moreRead less
Robust Automatic Speaker Diarisation of Audio Documents by Exploiting Prior Sources of Information. Speaker Diarisation, the task of determining who spoke when, is a technology fundamental in deriving intelligent information from audio and multimedia resources. The requirement for efficient and accurate Speaker Diarisation systems, portable across different domains is heightened by the explosive growth of audio and multimedia archives online and throughout the world. This research will provide t ....Robust Automatic Speaker Diarisation of Audio Documents by Exploiting Prior Sources of Information. Speaker Diarisation, the task of determining who spoke when, is a technology fundamental in deriving intelligent information from audio and multimedia resources. The requirement for efficient and accurate Speaker Diarisation systems, portable across different domains is heightened by the explosive growth of audio and multimedia archives online and throughout the world. This research will provide the foundation for a commercial service of automatic Speaker Diarisation to be developed, growing Australia's impact on the information and communications technology (ICT) sector. The outcome of this research will also assist in the tracking of terrorist and unlawful activity by enabling effective intelligence gathering from different audio sources.Read moreRead less
Design of Neonatal Seizure Diagnosis Methods Using Time-Frequency Signal Processing Techniques. Seizures occur in approximately 0.5% of all newborns. They are often the only indicator of an early dysfunction in central nervous system (CNS). Their occurrence raises concerns about the underlying cause, its effect on the brain, and the appropriate treatment. Newborn seizures are mostly sub-clinical and only detected through the Electroencephalogram. For an efficient diagnosis, seizure classificatio ....Design of Neonatal Seizure Diagnosis Methods Using Time-Frequency Signal Processing Techniques. Seizures occur in approximately 0.5% of all newborns. They are often the only indicator of an early dysfunction in central nervous system (CNS). Their occurrence raises concerns about the underlying cause, its effect on the brain, and the appropriate treatment. Newborn seizures are mostly sub-clinical and only detected through the Electroencephalogram. For an efficient diagnosis, seizure classification systems were proposed based on visual observations. This project proposes developing a novel approach to automate the classification process using time-frequency (TF) signal processing techniques based on the multi-channel characteristics of the seizure; namely: A) TF signature B) origin, and C) propagation behaviour.Read moreRead less
Making demonstrably reliable forensic voice comparison a practical everyday reality in Australia. To assist Australian law-enforcement agencies and courts in the process of the conviction of the guilty and the exoneration of the innocent, this project will develop and test a practical and demonstrably reliable forensic voice comparison system for use with Australian voices. This will allow forensic scientists to produce reliable strength of evidence statements for presentation in court using the ....Making demonstrably reliable forensic voice comparison a practical everyday reality in Australia. To assist Australian law-enforcement agencies and courts in the process of the conviction of the guilty and the exoneration of the innocent, this project will develop and test a practical and demonstrably reliable forensic voice comparison system for use with Australian voices. This will allow forensic scientists to produce reliable strength of evidence statements for presentation in court using the same evaluative framework as used with DNA. In addition, application of the system during criminal investigations may lead to the refocussing of investigations on other suspects, or may help leverage guilty pleas, thus saving substantial time and money.Read moreRead less
A humanised sensory neuron high-throughput screening platform . Sensory neurons are responsible for converting external stimuli such as touch or temperature into graded electrical signals that allow us to interact with the world around us. However, unlike other cell types, sensory neurons cannot proliferate and thus must be removed from human cadavers, or animals, in order to study their pharmacology and function. This limits our ability to understand neuronal signalling pathways. This project a ....A humanised sensory neuron high-throughput screening platform . Sensory neurons are responsible for converting external stimuli such as touch or temperature into graded electrical signals that allow us to interact with the world around us. However, unlike other cell types, sensory neurons cannot proliferate and thus must be removed from human cadavers, or animals, in order to study their pharmacology and function. This limits our ability to understand neuronal signalling pathways. This project aims to use sensory neurons derived from human stem cells to develop and optimise assays that can be used to study the pharmacology and function of human sensory neurons in vitro. This enhances access to critical model systems and technology platforms and removes the need for isolation of cells from cadavers. Read moreRead less
Audio Visual Speech Recognition. Even though significant advances have been made in automatic speech recognition using acoustic information, the recognition accuracies are still poor in noisy and hostile environments such as in crowds, traffic, factory floors etc. In many of these applications visual information is or can easily be made available in addition to the audio. The aim of this project is to achieve an order of magnitude improvement in speech recognition accuracies in adverse environme ....Audio Visual Speech Recognition. Even though significant advances have been made in automatic speech recognition using acoustic information, the recognition accuracies are still poor in noisy and hostile environments such as in crowds, traffic, factory floors etc. In many of these applications visual information is or can easily be made available in addition to the audio. The aim of this project is to achieve an order of magnitude improvement in speech recognition accuracies in adverse environments by joint processing and modelling of the acoustic modality with visual information in the form of lip shapes and movements. The outcomes will be useful in human computer interaction in adverse environments as well as in the transcription and mining of multimedia data.
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Automated vision-based aircraft collision warning technologies. Australia is a sparsely populated country with a number of unique airspace features. This project will investigate novel vision-based collision warning systems that can improve safety for piloted aircraft and also help achieve integration of UASs (Uninhabited Aerial Systems) into national airspace. The benefits of UAS technologies are particularly relevant to Australia, as governments and industry struggle to cope with providing equ ....Automated vision-based aircraft collision warning technologies. Australia is a sparsely populated country with a number of unique airspace features. This project will investigate novel vision-based collision warning systems that can improve safety for piloted aircraft and also help achieve integration of UASs (Uninhabited Aerial Systems) into national airspace. The benefits of UAS technologies are particularly relevant to Australia, as governments and industry struggle to cope with providing equivalent levels of service to remote communities over vast distances (or border protection of vast regions). The population base of Australia requires that cost-effective solutions are sought to meet this end. Read moreRead less
Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not re ....Inhibition of pro-inflammatory cytokine secretion- A new route to therapeutics of chronic inflammatory disease. Chronic inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, affect millions of people leading to considerable suffering, economic loss and premature death. Anti-TNF treatments have recently shown success in the treatment of rheumatoid arthritis, inflammatory bowel disease and other conditions, however, a substantial number of patients (~50%) do not respond to the current TNF treatments. Improved anti-TNF strategies would provide enhanced health outcomes and welcome relief to many Australians. In addition, the economic benefit of the TNF market is very substantial. Therefore the potential impact of this research is very high both for health care and economical potential.Read moreRead less
The development of tyrosine kinase inhibitors for the treatment of inflammation and malignant disease. Through the combination of expertise from the Industry partner and the Hume group this project aims to develop specific inhibitors of the CSF-1 receptor protein tyrosine kinase in order to demonstrate their efficacy as modulators of CSF-1 dependent macrophage and tumour cell function in vitro. The expected outcome will be a lead set of targets which can be further assessed for therapeutic pote ....The development of tyrosine kinase inhibitors for the treatment of inflammation and malignant disease. Through the combination of expertise from the Industry partner and the Hume group this project aims to develop specific inhibitors of the CSF-1 receptor protein tyrosine kinase in order to demonstrate their efficacy as modulators of CSF-1 dependent macrophage and tumour cell function in vitro. The expected outcome will be a lead set of targets which can be further assessed for therapeutic potential in clinical trials.Read moreRead less
The next generation speaker recognition system. The next generation of speaker recognition technologies developed through this project will enable secure person authentication by voice in financial transactions and benefit the community through the elimination of identity fraud. This project will safeguard Australia by identifying criminal suspects using their voice and combat terrorism by using voice to locate and track terrorists.