Inverse and related problems in statistics. Modern statistical inverse problems arise in fields from astronomy and biology to engineering and finance. Sometimes the problems involve the analysis of small samples of very high dimensional data, and are central to information aquisition in areas such as genomics and signal analysis. All these topics are of significant national importance, and their solution will bring national and community benefits. In addition, the program to which the proposa ....Inverse and related problems in statistics. Modern statistical inverse problems arise in fields from astronomy and biology to engineering and finance. Sometimes the problems involve the analysis of small samples of very high dimensional data, and are central to information aquisition in areas such as genomics and signal analysis. All these topics are of significant national importance, and their solution will bring national and community benefits. In addition, the program to which the proposal will lead will be used extensively for research training. In Australia, where the demand for research-trained statisticians greatly exceeds supply, this contribution to the nation and the community will be particularly important. Read moreRead less
New and computationally feasible methods of constructing efficient and exact confidence limits from count data. Biological and health science data is commonly in the form of counts. The statistical analysis of such data should be (a) efficient i.e. it should not, in effect, throw away valuable data, (b) exact i.e. it should have precisely known statistical properties and (c) computationally feasible. Kabaila and Lloyd (1997-2001) have proposed and analysed a radically new method of confidence li ....New and computationally feasible methods of constructing efficient and exact confidence limits from count data. Biological and health science data is commonly in the form of counts. The statistical analysis of such data should be (a) efficient i.e. it should not, in effect, throw away valuable data, (b) exact i.e. it should have precisely known statistical properties and (c) computationally feasible. Kabaila and Lloyd (1997-2001) have proposed and analysed a radically new method of confidence limit construction which, for the first time, possesses all of these requirements. The purpose of the project is to establish further theoretical support for the new method, to develop efficient computational algorithms and to write easy-to-use computer programs for its practical use.Read moreRead less
Maximizing solid state Nuclear Magnetic Resonance (NMR) with maximum entropy. Nuclear magnetic resonance is an essential technology for the characterisation of important industrial and biomedical molecules, molecular chains and complexes. This project aims to considerably expand the fundamental capability of experimental techniques for the study of materials in the solid state, in particular for a new class of biological nanoparticle. These advances will have important global implications for re ....Maximizing solid state Nuclear Magnetic Resonance (NMR) with maximum entropy. Nuclear magnetic resonance is an essential technology for the characterisation of important industrial and biomedical molecules, molecular chains and complexes. This project aims to considerably expand the fundamental capability of experimental techniques for the study of materials in the solid state, in particular for a new class of biological nanoparticle. These advances will have important global implications for research into life-saving therapeutic strategies aimed at many pharmaceutical targets embedded in cell membranes, protein misfolding disorders such as Alzheimer's disease and Huntington's disease, as well as development of the next generation of "green" plastics and other advanced polymers.Read moreRead less
Theory and application of computer-intensive, nonparametric statistical methods. The availability of increasingly powerful computing equipment continues to have a dramatic impact on statistical methods and thinking. These developments, combined with new technologies for generating data, are driving substantial changes in statistics, ranging from the types of problems being solved to the sorts of methods used to solve them. Both the problems and their solutions are of substantial national and c ....Theory and application of computer-intensive, nonparametric statistical methods. The availability of increasingly powerful computing equipment continues to have a dramatic impact on statistical methods and thinking. These developments, combined with new technologies for generating data, are driving substantial changes in statistics, ranging from the types of problems being solved to the sorts of methods used to solve them. Both the problems and their solutions are of substantial national and community benefit. They will be the subject of high-level research supported by this proposal. Read moreRead less
Nonparametric Statistical Methods -- New Directions, Theory and Applications. The research program will take Australia to the forefront of contemporary work in nonparametric statistics, and assist greatly in the training of a new generation of Australian statistical scientists. It will contribute significantly to restoring the health of this strategically important field, in Australian universities and in the nation more generally. The projects outlined in the proposal address problems arising ....Nonparametric Statistical Methods -- New Directions, Theory and Applications. The research program will take Australia to the forefront of contemporary work in nonparametric statistics, and assist greatly in the training of a new generation of Australian statistical scientists. It will contribute significantly to restoring the health of this strategically important field, in Australian universities and in the nation more generally. The projects outlined in the proposal address problems arising in astronomy, economics, engineering, defence, health and image analysis, but the potential areas of impact are broader even than this. This diversity illustrates the extraordinary potential, and strategic significance, of statistics to Australia. Read moreRead less
Special Research Initiatives - Grant ID: SR0354716
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Energetically Open Systems Research Network Study. Conceptual frameworks arising in the physical sciences, such as non-equilibrium statistical mechanics and thermodynamics, synergetics, chaos and dynamical systems theory, are seminal in the emerging science of complexity. This study will lay the groundwork for a network to link Australian and overseas research on these fundamental concepts, and their application within the context of entropy-producing systems vital to the long-term sustainabilit ....Energetically Open Systems Research Network Study. Conceptual frameworks arising in the physical sciences, such as non-equilibrium statistical mechanics and thermodynamics, synergetics, chaos and dynamical systems theory, are seminal in the emerging science of complexity. This study will lay the groundwork for a network to link Australian and overseas research on these fundamental concepts, and their application within the context of entropy-producing systems vital to the long-term sustainability of the earth - oceans, atmosphere, biosphere, CO2-free energy production, space and solar environment. The network would facilitate the development of young investigators and be linked into wider complex systems networks such as the CSIRO Centre for Complex Systems Science.Read moreRead less
Computational Nanofluidics. This project will generate an increased level of skill and expertise in Australia in the emerging science of nanotechnology. To realise the promise of nanotechnology, a means of controlled propulsion on the nano scale is vital. A deeper understanding of nanofluidics that allows greater predictive capacities can greatly aid this realisation. It is highly likely that computational nanofluidics will play as important a role in nanotechnology based industries as computat ....Computational Nanofluidics. This project will generate an increased level of skill and expertise in Australia in the emerging science of nanotechnology. To realise the promise of nanotechnology, a means of controlled propulsion on the nano scale is vital. A deeper understanding of nanofluidics that allows greater predictive capacities can greatly aid this realisation. It is highly likely that computational nanofluidics will play as important a role in nanotechnology based industries as computational fluid dynamics (CFD) currently plays in today's manufacturing, automotive and aerospace industries. The skills and knowledge gained from this project will enhance our international competitiveness in this area. Read moreRead less
Mathematical studies on the statistical properties of complex systems. Introduced in the late `50's to model nuclear spectra, random matrices are now standard in the theory of quantum chaos, mesoscopic phenomena and disordered systems. These are all examples of physical complex systems, characterized by unknown interactions leading to predictable behaviour due to symmetries. Vast mathematical structures result from the symmetries - integrable systems, Painleve equations, Macdonald polynomial the ....Mathematical studies on the statistical properties of complex systems. Introduced in the late `50's to model nuclear spectra, random matrices are now standard in the theory of quantum chaos, mesoscopic phenomena and disordered systems. These are all examples of physical complex systems, characterized by unknown interactions leading to predictable behaviour due to symmetries. Vast mathematical structures result from the symmetries - integrable systems, Painleve equations, Macdonald polynomial theory to name a few. These structures will be further developed, leading to the analytic form of distribution functions quantifying classes of complex systems. Analogous statistical quantification is the essence of recently proposed methods to analyze artificial complex systems such as the stock market.Read moreRead less