The Role Of Capsid Protein Nucleolar Localisation In Chikungunya Virus: Implications For Vaccine Development
Funder
National Health and Medical Research Council
Funding Amount
$520,520.00
Summary
Chikungunya virus (CHIKV) is a globally widespread mosquito-borne alphavirus capable of causing considerable human morbidity and mortality. With no CHIKV vaccine or antiviral available this proposal aims to develop a live attenuated CHIKV vaccine, rationally designed by investigating the host cell nucleolar trafficking of CHIKV capsid protein. This vaccine has the potential to provide cross-protection against additional arthritogenic alphaviruses endemic to Australia such as Ross River virus.
TSGA IPA: The Australian Aquatic Animal Health And Vaccine Centre: First Phase To Establish Atlantic Salmon Biosecure Fish Facility Capabilities And Develop Strategy For An Australian Centre Of Excellence
Funder
Fisheries Research and Development Corporation
Funding Amount
$1,694,600.00
Summary
Commercial in confidence. To know more about this project please contact FRDC. Objectives: Commercial in confidence
Production Of Antibodies Against Toxins Involved In Ciguatera Fish Poisoning
Funder
Fisheries Research and Development Corporation
Funding Amount
$87,050.00
Summary
Objectives: 1. Develop method of detection of ciguatoxin (CTX) to extract & purify sufficient CTX to service requirements of program. 2. Develop an en enzyme imunassay for measuring anti-CTX production. 3. Develop method of schedule immunisation to allow production of monoclonal antibodies
SCRC: Seafood CRC Participant Sponsorship To 2011 National Seafood Industry Leadership Program
Funder
Fisheries Research and Development Corporation
Summary
The CRC is all about capacity building within the CRC participants and the FRDC Seafood Leadership Program enables the opportunity to invest in people who are keen to show their leadership potential. Investing in Leadership, and the associated networks and cross stakeholder understanding is seen as vitally important for all sectors to be able to contribute to debate, drive change and address challenges in order to enable the Seafood CRC and the industry to reach its potential.
FRDC has obtained Board approval FRDC Board Meeting # 194, 24 November 2022) to become a member of CRC SAAFE and investment up to $1.0 million. This project is needed to manage the FRDC investment that will be comprised of investments seafood related projects. Conducting projects within CRC SAAFE will provide linkages to additional resources, expertise and knowledge sharing that will improve project outputs and foster national collaboration in addition to that currently provided by the FRDC. Th ....FRDC has obtained Board approval FRDC Board Meeting # 194, 24 November 2022) to become a member of CRC SAAFE and investment up to $1.0 million. This project is needed to manage the FRDC investment that will be comprised of investments seafood related projects. Conducting projects within CRC SAAFE will provide linkages to additional resources, expertise and knowledge sharing that will improve project outputs and foster national collaboration in addition to that currently provided by the FRDC. This will include the research and industry participants that are partners of CRC SAAFE. Objectives: 1. Best practice AMR mitigation and management in the seafood industry and the aquatic environment. 2. Improved biosecurity and animal welfare through development of vaccines to minimise use of antibiotics. Read moreRead less
Development Of Vaccines And Rapid Diagnostic Monoclonal Antibodies Against Micro-organisms Associated With Diseases Of Wild And Cultured Finfish And Shellfish
Funder
Fisheries Research and Development Corporation
Funding Amount
$166,772.00
Summary
Objectives: 1. Identification and characterisation of species-specific antigenic determinants that are heat-stable components of the lipopolysaccharide (LPS) on pathogenic gram-negative bacteria. 2. Prepare a library of species and genus-specific monoclonal antibodies against the heat-stable LPS components of pathogenic gram-negative bacteria 3. Select appropriate hybridomas, that produce high affinity monoclonal antibodies, for transfer to strategic companies 4. Complete t ....Objectives: 1. Identification and characterisation of species-specific antigenic determinants that are heat-stable components of the lipopolysaccharide (LPS) on pathogenic gram-negative bacteria. 2. Prepare a library of species and genus-specific monoclonal antibodies against the heat-stable LPS components of pathogenic gram-negative bacteria 3. Select appropriate hybridomas, that produce high affinity monoclonal antibodies, for transfer to strategic companies 4. Complete the testing of specific LPS fragments extracted from one Vibrio species to produce vaccine against all Vibrio pathogens 5. Use the same approach as in (4) to test the genus-specific protection afforded by similar LPS fragrments extracted from additional pathogens, particularly Aeromonas salmonicida 6. Develop and market commercial products for use rapid diagnoses and in research of infections of wild and cultured fish and shellfish Read moreRead less
Determining the social value of extreme, mixed-use urban developments. Using an Adelaide case study, UCity, this project will investigate the social benefit of building mixed-use vertical communities in the Australian urban context. Using an innovative Social Value Framework, the project will establish and demonstrate the multi-dimensional impacts of such developments in practice. The project utilises citizen science for real time auditing of the built environment by residents and users; smart t ....Determining the social value of extreme, mixed-use urban developments. Using an Adelaide case study, UCity, this project will investigate the social benefit of building mixed-use vertical communities in the Australian urban context. Using an innovative Social Value Framework, the project will establish and demonstrate the multi-dimensional impacts of such developments in practice. The project utilises citizen science for real time auditing of the built environment by residents and users; smart technologies for environmental and behavioural monitoring; and data analytics and design automation for spatial analysis of building use. The results will inform new models of sustainable high-rise, mixed-use buildings; providing evidence for a Social Value Framework to become a core consideration in Australian industry.Read moreRead less