The Role Of Capsid Protein Nucleolar Localisation In Chikungunya Virus: Implications For Vaccine Development
Funder
National Health and Medical Research Council
Funding Amount
$520,520.00
Summary
Chikungunya virus (CHIKV) is a globally widespread mosquito-borne alphavirus capable of causing considerable human morbidity and mortality. With no CHIKV vaccine or antiviral available this proposal aims to develop a live attenuated CHIKV vaccine, rationally designed by investigating the host cell nucleolar trafficking of CHIKV capsid protein. This vaccine has the potential to provide cross-protection against additional arthritogenic alphaviruses endemic to Australia such as Ross River virus.
Using acoustic retroreflection in architecture to improve rooms for speech. This project aims to discover how a novel form of acoustic treatment can improve acoustics for speech in rooms such as classrooms and open-plan offices. The project will generate new knowledge on the theory, design, and effects of acoustically retroreflective surfaces in room acoustics. Expected outcomes include solutions for effective acoustic retroreflectors, knowledge on how retroreflection influences people’s voice r ....Using acoustic retroreflection in architecture to improve rooms for speech. This project aims to discover how a novel form of acoustic treatment can improve acoustics for speech in rooms such as classrooms and open-plan offices. The project will generate new knowledge on the theory, design, and effects of acoustically retroreflective surfaces in room acoustics. Expected outcomes include solutions for effective acoustic retroreflectors, knowledge on how retroreflection influences people’s voice regulation and sound quality perception, and guidelines and simulation tools for integrating retroreflective treatments to improve speaking comfort. This should provide significant benefits including opportunities to resolve seemingly intractable design dilemmas in the acoustics of education and workplace environments.Read moreRead less
Surfacing urban wetlands in two urban renewal sites in Sydney. Urban wetlands in Australia provide benefits for climate change mitigation, pollution reduction, habitat provision and socioecological connection. However, in large cities like Sydney, urban wetlands are unseen because undergrounded, and, therefore not adequately understood. This illegibility, and loss of understanding by residents, planners and policy makers impedes wetlands' good management. This project surfaces wetlands through v ....Surfacing urban wetlands in two urban renewal sites in Sydney. Urban wetlands in Australia provide benefits for climate change mitigation, pollution reduction, habitat provision and socioecological connection. However, in large cities like Sydney, urban wetlands are unseen because undergrounded, and, therefore not adequately understood. This illegibility, and loss of understanding by residents, planners and policy makers impedes wetlands' good management. This project surfaces wetlands through visualisation in a multimodal knowledge platform focusing on two urban renewal sites, Green Square and Marrickville South. We leverage design ethnography to develop resources for strengthening multiple stakeholders’ socioecological engagement through methods empowering just, creative and open participation.Read moreRead less
Muscle memory: The key to novel interactive memory support systems. This project aims to investigate how the use of muscle memory as a deliberate interaction design resource can effectively support declarative memory. The project brings together memory interaction design and bodily activity design to address increasing concerns surrounding Australians’ memory. By investigating muscle memory in interaction design, the project is expected to advance international understanding of scholarly and pra ....Muscle memory: The key to novel interactive memory support systems. This project aims to investigate how the use of muscle memory as a deliberate interaction design resource can effectively support declarative memory. The project brings together memory interaction design and bodily activity design to address increasing concerns surrounding Australians’ memory. By investigating muscle memory in interaction design, the project is expected to advance international understanding of scholarly and practical processes that complement design for declarative memory. The project will lay the foundation for extending research which will assist movement, rehabilitation, health and educational sports practitioners that can create engaging experiences that use muscle memory for the benefit of all Australians.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100779
Funder
Australian Research Council
Funding Amount
$396,935.00
Summary
Co-design using participatory urban media. This project aims to use participatory urban media to test the effectiveness of co-designed screen-based interfaces in helping government and urban planners to better understand and design for rapidly urbanising cities by engaging designers and city stakeholders. Using Chongqing in China as a case study, it intends to generate new knowledge about the value of participatory urban media installations as transformative interventions in traditional urban de ....Co-design using participatory urban media. This project aims to use participatory urban media to test the effectiveness of co-designed screen-based interfaces in helping government and urban planners to better understand and design for rapidly urbanising cities by engaging designers and city stakeholders. Using Chongqing in China as a case study, it intends to generate new knowledge about the value of participatory urban media installations as transformative interventions in traditional urban design. Expected outcomes include a reproducible approach to co-designing urban media for participatory engagement between city stakeholders and citizens which should significantly increase the capacity of Australia-China design partnerships to manage pressing regional urban and placemaking problems.Read moreRead less
Integrated Autonomous Housing for Remote Australian Communities: Analysis, Synthesis and Testing. At remote mining communities, little consideration is given to comfort or energy efficiency in housing - services have not been optimised to minimise greenhouse gas emissions, water consumption and solid waste. This project will address these environmental issues and the associated social problems by combining the resources of BHP Billiton and the University of Newcastle to develop a model for remot ....Integrated Autonomous Housing for Remote Australian Communities: Analysis, Synthesis and Testing. At remote mining communities, little consideration is given to comfort or energy efficiency in housing - services have not been optimised to minimise greenhouse gas emissions, water consumption and solid waste. This project will address these environmental issues and the associated social problems by combining the resources of BHP Billiton and the University of Newcastle to develop a model for remote housing. The project aims to design and test an integrated low impact or autonomous transportable house. The results of this research are applicable to remote defence sites, small rural townships and Aboriginal communities as well as for international export.Read moreRead less
Place and parametricism: Provocations for the rethinking of design. This project aims to explore whether quantitative methods of digital and parametric design can adequately encompass place. Quantitative digital and parametric approaches increasingly dominate contemporary architecture, but people assume architectural design should be essentially oriented to questions of place. The project will operate through a set of studio provocations based on the fictional places of Mervyn Peake's Gormenghas ....Place and parametricism: Provocations for the rethinking of design. This project aims to explore whether quantitative methods of digital and parametric design can adequately encompass place. Quantitative digital and parametric approaches increasingly dominate contemporary architecture, but people assume architectural design should be essentially oriented to questions of place. The project will operate through a set of studio provocations based on the fictional places of Mervyn Peake's Gormenghast novels. The project is expected to clarify the nature of place and parametricism, and rethink what design itself might be.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100113
Funder
Australian Research Council
Funding Amount
$420,437.00
Summary
Interactions between volumetric units in modular buildings. This project aims to develop an in-depth understanding of the interactions between volumetric units in modular buildings to develop integration strategies for the interconnection of modules. The uptake of modular construction has been hindered by the technical complexities of the design process for manufacture and assembly, in particular the flexible connection of services. By addressing significant gaps in the guidance on the design of ....Interactions between volumetric units in modular buildings. This project aims to develop an in-depth understanding of the interactions between volumetric units in modular buildings to develop integration strategies for the interconnection of modules. The uptake of modular construction has been hindered by the technical complexities of the design process for manufacture and assembly, in particular the flexible connection of services. By addressing significant gaps in the guidance on the design of modular interconnections and their integration strategies, this project expects to enhance the industry’s capacity to adopt safe, economical and standardised designs of modular systems. This project should significantly reduce the risk in decision making in modular construction, and transformation to advanced building manufacturing technologies in Australia and beyond.Read moreRead less
A Design History of Australian HIV/AIDS Public Health Campaigns 1983-2004. This project investigates the differing roles of governments and community organisations as influential factors in the formulation of graphic representations which characterise the prevention campaigns used in the HIV/AIDS epidemic in Australia 1983-2004. It explains how graphic representations, functioning as an index of official and public responses to the epidemic, impact on the aesthetic and professional autonomy of t ....A Design History of Australian HIV/AIDS Public Health Campaigns 1983-2004. This project investigates the differing roles of governments and community organisations as influential factors in the formulation of graphic representations which characterise the prevention campaigns used in the HIV/AIDS epidemic in Australia 1983-2004. It explains how graphic representations, functioning as an index of official and public responses to the epidemic, impact on the aesthetic and professional autonomy of the designer. Complimenting existing quantitative assessments this study uses a textual-visual analysis and triangulation method to demonstrate the agency of these institutional constraints placed within the broader range of material forms relating to the campaigns including brochures, posters, and videos.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100730
Funder
Australian Research Council
Funding Amount
$414,216.00
Summary
Designing for early engagement and wellbeing in palliative care. This project aims to generate design guidelines to assist architects in creating better palliative care environments to mitigate the stress associated with end-of-life events for patients, their families and healthcare teams. Facing death, either one’s own or that of a family member, is one of life’s most difficult experiences. Targeted design interventions can encourage early engagement with palliative care, enhance communication ....Designing for early engagement and wellbeing in palliative care. This project aims to generate design guidelines to assist architects in creating better palliative care environments to mitigate the stress associated with end-of-life events for patients, their families and healthcare teams. Facing death, either one’s own or that of a family member, is one of life’s most difficult experiences. Targeted design interventions can encourage early engagement with palliative care, enhance communication and social support in palliative care environments and support staff to deliver optimal patient care. These factors have all been shown to contribute positively to wellbeing. This project will provide benefits for patients, their families and healthcare teams.Read moreRead less