Biosensor Based Clinical-decision Support For Patients With Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$691,933.00
Summary
Heart Failure (HF) is a progressive disease and a major global public health concern. HF accounts for a substantial number of hospitalisations, major healthcare resource utilisation and costs. We aim to engineer biosensor platform to stratify the risk in HF patients will revolutionise current management of HF by providing the cardiologist information to risk stratify patients based on protein signature. This will lead to a substantial paradigm shift in clinical practice.
Case-control Study To Promote Oral Health In Asthmatic Children:Natural Dietary Strategies To Conserve Teeth Erosion
Funder
National Health and Medical Research Council
Funding Amount
$112,500.00
Summary
Asthmatic children are at risk of dental corrosion, from medications that shut off saliva. Saliva protects teeth from acids in soft drinks and stomach-acid reflux. Dentist, William George Young and Nutritionist, Peter Davies, at the University of Queensland study children’s teeth, diet and lifestyles for the best natural methods to promote oral health. They will counsel parents and children on diets that conserve the teeth from dental erosion and decay by salivary stimulation. Patients need to s ....Asthmatic children are at risk of dental corrosion, from medications that shut off saliva. Saliva protects teeth from acids in soft drinks and stomach-acid reflux. Dentist, William George Young and Nutritionist, Peter Davies, at the University of Queensland study children’s teeth, diet and lifestyles for the best natural methods to promote oral health. They will counsel parents and children on diets that conserve the teeth from dental erosion and decay by salivary stimulation. Patients need to self-manage their asthma and diets to avoid negative outcomes and costs in acute medical and dental therapy for these two chronic conditions.Read moreRead less
Analysis Of The Effectiveness Of A Simple, Inexpensive, Saliva-based Caries-risk Test
Funder
National Health and Medical Research Council
Funding Amount
$29,688.00
Summary
The project aims to develop a test with the capacity to identify children at risk of developing caries (dental decay) so they can benefit from preventive care. The effectiveness of the test will be assessed by how well it correlates with currently available tests and whether it can predict caries development in children classified into risk groups on the basis of the test. The test promises to be predictive of caries-risk, inexpensive, easy to interpret and rapid when compared to those currently ....The project aims to develop a test with the capacity to identify children at risk of developing caries (dental decay) so they can benefit from preventive care. The effectiveness of the test will be assessed by how well it correlates with currently available tests and whether it can predict caries development in children classified into risk groups on the basis of the test. The test promises to be predictive of caries-risk, inexpensive, easy to interpret and rapid when compared to those currently available commercially.Read moreRead less
Oral Cancer is a devastating disease that is associated with poor survival and greatly impacts the lives who do survive. This project aims to develop a tool to inspect the changes of molecules called microRNAs, in saliva and skin cells of the mouth, collected using a simple, painless method, which will help to predict the risk of patients developing oral cancer.
Chronic Oral Graft-versus-host Disease: Clinical Risk Factors, Biochemical Markers Of Disease Activity And Novel Therapeutics
Funder
National Health and Medical Research Council
Funding Amount
$134,184.00
Summary
Chronic graft-versus-host disease (GVHD) is a serious complication of bone marrow transplantation. The oral cavity is often affected. Aims: 1.Identify and validate risk factors for oral GVHD 2.Assess if specific salivary components reflect disease activity 3.Trial novel therapeutic for GVHD-associated dry mouth Saliva testing may offer a non-invasive method to monitor oral GVHD. Also, new and effective topical agents are greatly needed and will improve therapeutic options in oral GVHD