New Technologies for Second Generation Search and Rescue. This project aims to improve the Cospas-Sarsat search and rescue system to ensure faster, more reliable, more accurate, and more cost-effective search and rescue operations, ultimately saving lives. The satellite-based Cospas-Sarsat system has assisted with the emergency rescue of more than 35 000 lives worldwide since its introduction in 1982. A second generation of this system is currently under development, promising to significantly i ....New Technologies for Second Generation Search and Rescue. This project aims to improve the Cospas-Sarsat search and rescue system to ensure faster, more reliable, more accurate, and more cost-effective search and rescue operations, ultimately saving lives. The satellite-based Cospas-Sarsat system has assisted with the emergency rescue of more than 35 000 lives worldwide since its introduction in 1982. A second generation of this system is currently under development, promising to significantly improve detection rate and localisation accuracy. However, in an emergency, the system’s performance is often compromised due to interference and atmospheric effects, leading to false detections that waste valuable resources. This project aims to develop novel techniques to improve this performance.Read moreRead less
Dissecting The Molecular Mechanisms Underlying Muscle Pathology In Duchenne Muscular Dystrophy (DMD)
Funder
National Health and Medical Research Council
Funding Amount
$375,856.00
Summary
Duchenne Muscular Dystrophy (DMD) is a genetic disease affecting 1-3,500 newborn males worldwide annually. The disease is characterized by muscle wasting, subsequently resulting in fatality in the late teens to the late 20's. To date there is no cure and treatments are aimed improving quality of life. This project focuses on examining the mechanisms behind the disease to ultimately gain a better understanding in order to develop more effective therapies for the treatment of DMD.
New high-performance iterative error correction codes. This project develops new error correction codes to underpin the success of next-generation communications technologies. The nature of the project presents significant potential for project outcomes to be beneficial to the Australian telecommunications industry in a wide range of application areas from optical communication to digital broadcasting.
Molecular Mechanisms That Generate And Activate Muscle Stem Cells During Growth And Disease.
Funder
National Health and Medical Research Council
Funding Amount
$596,086.00
Summary
This study aims answer long standing questions in the field of muscle stem cells. Understanding how stem cell-driven muscle repair occurs has profound implications for our understanding of the pathology and treatment of muscle disease. Muscular dystrophies and myopathies are amongst the largest group of inherited disorders to afflict the human condition. It is our hope that the results of this research will lead to a better understanding of how treatments, stem cell based or otherwise, could be ....This study aims answer long standing questions in the field of muscle stem cells. Understanding how stem cell-driven muscle repair occurs has profound implications for our understanding of the pathology and treatment of muscle disease. Muscular dystrophies and myopathies are amongst the largest group of inherited disorders to afflict the human condition. It is our hope that the results of this research will lead to a better understanding of how treatments, stem cell based or otherwise, could be employed to correct such disorders.Read moreRead less
Seeing Is Believing: Imaging Muscle Maintenance And Repair
Funder
National Health and Medical Research Council
Funding Amount
$727,191.00
Summary
We will characterise the behaviour of muscle stem cells in vivo within their micro-environment in normal and regenerating adult muscles, using high-end imaging technologies and mouse lines that we recently created. This will allow correlating cellular behaviours with the activation of signaling pathways, chosen for their likely role in the activation of satellite cells. We will then modulate the activity of these pathways in the satellite cell niche to evaluate their function.
Roles Of Vitamin D In Skeletal Muscle And Satellite Cells
Funder
National Health and Medical Research Council
Funding Amount
$380,891.00
Summary
Vitamin D deficiency leads to muscle pain and weakness that are reversible with vitamin D supplementation. However, precise biological effects of vitamin D in skeletal muscle are unclear. In this fellowship, novel mouse models and innovative techniques will be used to examine vitamin D signalling pathways in whole muscle and muscle stem cells. Ultimately, the therapeutic potential of the vitamin D pathway in treatment of muscle disorders and age-related muscle wasting will be explored.
Satellite Data Communications for Remote Sensing and Broadband Connectivity. The remote, distributed location of many of Australia's primary industries preclude the use of consumer-oriented terrestrial wireless broadband services. In many instances, satellite communications provides the only feasible means of connectivity for telemetry, supervisory control and data acquisition, tracking and fleet management. Meteorology, remote sensing, irrigation, mining, oil and gas exploration, and fisheries ....Satellite Data Communications for Remote Sensing and Broadband Connectivity. The remote, distributed location of many of Australia's primary industries preclude the use of consumer-oriented terrestrial wireless broadband services. In many instances, satellite communications provides the only feasible means of connectivity for telemetry, supervisory control and data acquisition, tracking and fleet management. Meteorology, remote sensing, irrigation, mining, oil and gas exploration, and fisheries are just a few examples of high-value applications of particular significance to Australia. This project will develop bandwidth efficient satellite communications technologies that greatly reduce cost and pave the way toward new market opportunities for broadband access and telemetry applications. Read moreRead less
Downlinks for Future Earth Observation Satellites: Breaking the Bottlenecks. Future earth-observation satellites require gigabit transmission rates in higher frequency bands. Limitations in the radio frequency spectrum call for spectrally-efficient modulation schemes, which make gigabit data rates particularly challenging. This project aims to design a next-generation transmission scheme for future Ka-Band gigabit satellite downlinks, including novel approaches for dealing with channel effects s ....Downlinks for Future Earth Observation Satellites: Breaking the Bottlenecks. Future earth-observation satellites require gigabit transmission rates in higher frequency bands. Limitations in the radio frequency spectrum call for spectrally-efficient modulation schemes, which make gigabit data rates particularly challenging. This project aims to design a next-generation transmission scheme for future Ka-Band gigabit satellite downlinks, including novel approaches for dealing with channel effects such as group delay, ripple and non-linear satellite power amplifiers. The design intends to include high-speed signal processing and coding architectures, plus real-time signal synthesis and acquisition to allow realistic performance testing and optimisation with satellite hardware from Thales Alenia Space.Read moreRead less
Accurate Location Service for 3G Cellular Networks. The project aims to improve the accuracy of automatic location identification of GPS enabled handsets in third-generation cellular networks via a modified Differential GPS method. The proposed sub-metre location ability will be a value-added service of the network providers and will appeal to a wide sector of users. The challenge is to develop a cost effective solution by utilising existing network infrastructure. We propose to use the GPS timi ....Accurate Location Service for 3G Cellular Networks. The project aims to improve the accuracy of automatic location identification of GPS enabled handsets in third-generation cellular networks via a modified Differential GPS method. The proposed sub-metre location ability will be a value-added service of the network providers and will appeal to a wide sector of users. The challenge is to develop a cost effective solution by utilising existing network infrastructure. We propose to use the GPS timing units in 3G networks for deriving local GPS position corrections; and to transfer these corrections to the users via the 3G data bursts of the beacons or other user data broadcasts.Read moreRead less
Development of large scale expansion tubes. The aim of this proposal is to develop a high Mach number scramjet simulation capability by modifying the X3 superorbital expansion tube at UQ for high suborbital operation at very high total pressures. This will enable Australia to do true Mach number simulation at higher speeds than is possible anywhere else, and mantain an international advantage in the development of scramjet flight propulsion. It will also put Australian researchers in a strong p ....Development of large scale expansion tubes. The aim of this proposal is to develop a high Mach number scramjet simulation capability by modifying the X3 superorbital expansion tube at UQ for high suborbital operation at very high total pressures. This will enable Australia to do true Mach number simulation at higher speeds than is possible anywhere else, and mantain an international advantage in the development of scramjet flight propulsion. It will also put Australian researchers in a strong position to participate in the next generation of US ground testing facilities, foreshadowed by the recent NASA purchase of a large shock tunnel driver. It will enable Australia to maintain a position of leadership in the development of new space travel concepts.Read moreRead less