Insights Into The Acute Cerebral Lesion Of Childhood Diabetes And It's Neuropsychological Sequelae
Funder
National Health and Medical Research Council
Funding Amount
$416,000.00
Summary
Type 1 diabetes in childhood is a major cause of morbidity with an Australian prevalence of approximately 20 per 100,000 children under 15 years of age. The leading cause of death in type 1 diabetes in children and adolescents is diabetic ketoacidosis complicated by cerebral oedema (brain swelling), the origins of which remain unknown. This research is aimed at providing an insight into changes in the brain of children with diabetic ketoacidosis (DKA) and the relationship of these brain changes ....Type 1 diabetes in childhood is a major cause of morbidity with an Australian prevalence of approximately 20 per 100,000 children under 15 years of age. The leading cause of death in type 1 diabetes in children and adolescents is diabetic ketoacidosis complicated by cerebral oedema (brain swelling), the origins of which remain unknown. This research is aimed at providing an insight into changes in the brain of children with diabetic ketoacidosis (DKA) and the relationship of these brain changes to short and long term neuropsychological functioning. The major aim of this project is to provide an insight into brain changes of children with diabetic ketoacidosis (DKA) and the relationship of these brain changes to subseuqent brain function. This is a study where we will simply observe differences between newly diagnosed type 1 diabetic patients with no ktoacidosis, ketoacidosis or ketoacidosis with brain swelling over 6 months. We will measure brain function using various techniques includiung: magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), electrophysiology (EEG) and neuropsychological tests. The significance of this project is that it will provide insight into the brain impairment of diabetic patients with and without DKA, and with brain swelling in the context of DKA. By further clarifying the nature of brain impairment we will provide early intervention strategies to improve psychological development of the young patients with diabetes. In addition to this we hope to better understand the origins of brain swelling during DKA and design treatment protocols that will prevent this devastating complication.Read moreRead less
Alcohol, Angry Rumination, And Aggression: The Role Of Acute Impairment Of Executive Functioning
Funder
National Health and Medical Research Council
Funding Amount
$341,780.00
Summary
In Australia, alcohol-induced aggression imposes substantial psychological, public health, social, and economic burdens on victims, perpetrators, and society. When people drink and brood over interpersonal transgresssions, they are at increased risk of violence, even toward the innocent. The goal of the proposed research is to identify neuropsychological mechanisms that account for this increased aggression.
A Randomised Trial Of The Augmentation Of Cognitive Behaviour Therapy With Fluoxetine For Anxious School Refusing Youth
Funder
National Health and Medical Research Council
Funding Amount
$539,191.00
Summary
School refusing youth consistently suffer from anxiety and sometimes depression. They become severely emotionally distressed when taken to school and experience social and academic difficulties in the short and long term as well as psychiatric illness in adulthood. Our program investigates whether treatment can be improved by enhancing psychotherapy (cognitive behaviour therapy) which helps over half of anxious school refusing children, with antidepressant-anxiety medication compared to placebo.
A Healthy Promoting School Approach To Encourage Children To Wear Helmets
Funder
National Health and Medical Research Council
Funding Amount
$165,708.00
Summary
Each year around sixty Australians die as a result of bicycle crashes and thousands more are injured, some so severely they are permanently disabled. The largest proportion of the population affected by bicycle-related injuries are children and adolescents. These injuries are largely preventable if riders wore helmets. Some studies suggest wearing a helmet reduces the likelihood of head injury by more than 75%. Approximately 80% of Western Australian primary school students who ride to school we ....Each year around sixty Australians die as a result of bicycle crashes and thousands more are injured, some so severely they are permanently disabled. The largest proportion of the population affected by bicycle-related injuries are children and adolescents. These injuries are largely preventable if riders wore helmets. Some studies suggest wearing a helmet reduces the likelihood of head injury by more than 75%. Approximately 80% of Western Australian primary school students who ride to school wear a helmet. Students aged 10-12 years are on the cusp of a dramatic decline in helmet usage - secondary school students helmet usage rates are observed at 43%. This project aims to provide a supportive school environment for road users, and with the assistance of their peers, skill children with strategies and dialogue to resist peer pressure not to wear a helmet in order to arrest this rate of decline when they reach secondary school. This three-year study will compare the impact of a whole-school road safety intervention based on the health promoting school model to the standard road safety curriculum. For the study cohort ie: Year 5 - 6 students, the focus will be on bicycle safety, in particular, correct helmet usage. The intervention includes innovative participatory strategies to develop a supportive school environment for road users plus peer-teacher classroom activities that encourage the correct use of bicycle helmets for Year 5 - 6 students (and their parents). The intervention trial will be conducted with 30 Western Australian primary schools in 2000 and 2001. Other target groups of the intervention are teachers, Year 7 peer teachers, school administrators and the school community. Potential benefits of this project include the provision of a model health promoting school intervention to increase the frequency of correct helmet wearing by children which in time may lead to a reduction in bicycle-related morbidity and mortality in Western Australia.Read moreRead less
Evaluation Of The Effectiveness Of Mobile Preschool For Child Health And Development In Remote Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$456,369.00
Summary
This project is a retrospective study of the effectiveness of the NT Mobile Preschool Program using assessment data for children's emergent literacy, social and emotional competencies and health status. Effectiveness will be established by comparison with achievement and health status data for children not attending preschool and those in communities with no preschool service. The study will identify and describe the key factors influencing the health and learning outcomes of the three groups.
Adult Consequences Of Childhood Exposure To Psychological Trauma
Funder
National Health and Medical Research Council
Funding Amount
$292,530.00
Summary
The importance of childhood experience to adult adjustment (DOES THIS MAKE SENSE) is an issue of general public health interest. In particular, in the area of personality development, there are a number of theories concerning the importance of childhood experience and developmental stresses on later personality, development, psychological functioning and physical health. More recently there has been debate on the accuracy with which adults areable to remember traumatic experiences in childhood. ....The importance of childhood experience to adult adjustment (DOES THIS MAKE SENSE) is an issue of general public health interest. In particular, in the area of personality development, there are a number of theories concerning the importance of childhood experience and developmental stresses on later personality, development, psychological functioning and physical health. More recently there has been debate on the accuracy with which adults areable to remember traumatic experiences in childhood. This study will follow a group of 808 primary school children who were exposed to the 1983 Ash Wednesday bushfires in SOuth Australia. They were involved in a study which examined them two months, eight months and twenty six months after the disaster. This rich descriptive set of information about these children and their families forms an objective data base against which their adult recall of the experience can be judged. The symptoms of these children were also documented at the time as was their disaster exposure. The impact of this one event, in the context of the other developmental influences will be examined as determinants of their adjustment in adult life. Finally, there has been an increasing interest in the way that previous traumatic exposure influences the nature of the hormonal response to stress. Using a test of functioning of the cortisol system, the stress response of this population will be compared with a control population who were also studied at the time of the original disaster.Read moreRead less