Development of New Generation Magnetic Circular Dichroism Spectrometers. We are building two Magnetic Circular Dichroism (MCD spectrometers) to meet a rising need in the study of metallo-proteins and other molecules of biological interest. The PhD project described in this application will involve instrumentation design, interfacing and sampling handling development for biological samples. We wish to involve a Lastek, a scientific instrumentation company, in the possible commercial development o ....Development of New Generation Magnetic Circular Dichroism Spectrometers. We are building two Magnetic Circular Dichroism (MCD spectrometers) to meet a rising need in the study of metallo-proteins and other molecules of biological interest. The PhD project described in this application will involve instrumentation design, interfacing and sampling handling development for biological samples. We wish to involve a Lastek, a scientific instrumentation company, in the possible commercial development of aspects of this project.Read moreRead less
Integrated on-chip force and displacement sensors for high-speed atomic force microscopy of ultimate sensitivity. This project aims to develop next generation atomic force microscopy systems based on a novel interferometric method for on-chip force and displacement sensing. The proposed sensitivity improvement of two orders of magnitude over the present state-of-the-art will provide a disruptive innovation for various present and future nanotechnologies.
Towards a unified technology platform for sensing in liquids. Towards a unified technology platform for sensing in liquids. This project aims to use a new sensing platform for hydrocarbon monitoring in water to evolve optical on-chip position sensing of suspended micro-structures. Microelectromechanical systems dominate the world in sensing technology; they are common in smartphone, automotive, aerospace, and military applications. However, this multibillion dollar industry has failed to make ch ....Towards a unified technology platform for sensing in liquids. Towards a unified technology platform for sensing in liquids. This project aims to use a new sensing platform for hydrocarbon monitoring in water to evolve optical on-chip position sensing of suspended micro-structures. Microelectromechanical systems dominate the world in sensing technology; they are common in smartphone, automotive, aerospace, and military applications. However, this multibillion dollar industry has failed to make chem/bio sensing profitable, mostly due to the absence of a robust and compact read-out technology for sensing in liquids. This project is expected to lead to a unified parallel sensing platform of ultimate sensitivity delivering aqueous sensing for wide ranging applications and markets.Read moreRead less
Nanoparticle driven templating of microspheres as chromatographic materials. This project aims to pioneer a novel, high-performing class of nano-patterned core-shell particles as chromatographic materials. It will use advanced polymerization and particle preparation techniques in combination with degradable nanoparticles design, to enable the plug-and-play assembly of chromatographic columns. Size-exclusion chromatography (SEC) is one of the most important analytical techniques for polymer chem ....Nanoparticle driven templating of microspheres as chromatographic materials. This project aims to pioneer a novel, high-performing class of nano-patterned core-shell particles as chromatographic materials. It will use advanced polymerization and particle preparation techniques in combination with degradable nanoparticles design, to enable the plug-and-play assembly of chromatographic columns. Size-exclusion chromatography (SEC) is one of the most important analytical techniques for polymer chemistry. The expected outcomes of this project are faster measurement times and the possibility of imaging molecular weight distributions at a new level of detail. This project could place Australia at the cutting edge of size-exclusion chromatography phase design in partnership with a leading manufacturer of stationary phases.Read moreRead less
Bright x-ray beams from laser-driven microplasmas. This project aims to develop a new generation of bright, laser-like x-ray sources for laboratory use. X-ray sources underpin key diagnostic techniques in materials science, advancing applications from structural engineering through to ore processing and energy storage. However, the limited brightness of present-day laboratory x-ray sources restricts the utility and range of these diagnostic techniques. This research intends to use intense lasers ....Bright x-ray beams from laser-driven microplasmas. This project aims to develop a new generation of bright, laser-like x-ray sources for laboratory use. X-ray sources underpin key diagnostic techniques in materials science, advancing applications from structural engineering through to ore processing and energy storage. However, the limited brightness of present-day laboratory x-ray sources restricts the utility and range of these diagnostic techniques. This research intends to use intense lasers to create microscopic plasmas and drive high harmonic generation. The high harmonic generation process is already used to create laser-like ultraviolet light. By optimising the characteristics of the plasma medium, the project aims to extend bright high harmonic generation to the x-ray regime.Read moreRead less
Engineering the strength and consolidation of reclaimed soft soil. Engineering the strength and consolidation of reclaimed soft soil. This project aims to strengthen reclaimed soft soils by controlled desiccation. Soft soil is a significant engineering challenge for many industry sectors in Australia and worldwide. The disposal of dredged soft soil is costly and time-consuming, and failure of soft mine tailings is an environmental catastrophe that can cause loss of life and interrupt mining prod ....Engineering the strength and consolidation of reclaimed soft soil. Engineering the strength and consolidation of reclaimed soft soil. This project aims to strengthen reclaimed soft soils by controlled desiccation. Soft soil is a significant engineering challenge for many industry sectors in Australia and worldwide. The disposal of dredged soft soil is costly and time-consuming, and failure of soft mine tailings is an environmental catastrophe that can cause loss of life and interrupt mining production. This project will research the underlying processes of material behaviour, by developing new electromagnetic measurement and modelling methods to predict material strengths at the micro and macro scales during desiccation. The new approach is expected to lead to innovative solutions to bearing capacity and settlement problems associated with soft soils.Read moreRead less
New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses ....New hyphenated chromatographic and spectroscopic methods for oil analysis. This project aims to use novel chemical separation methods combined with spectroscopy to identify useful markers in olive oil and essential oil to ensure purity, quality and authenticity, which are all ongoing issues in these industries in Australia and overseas. The project plans to compare and integrate results of multidimensional gas chromatography combined with mass spectrometry and Fourier transform infrared analyses with data libraries to generate precise molecular identification. The outcome is expected to help monitor adulteration of oils and maintain the high quality standards of Australian produce.Read moreRead less
Microwave Detection of Structural Degradation in Maritime Industry. Novel applications of microwave technology to inspection systems in marine infrastructure will transform industry practice. By utilizing multi-mode antennas, the project aims to develop a gold-standard in microwave inspection, delivering more accurate and early detection of defects. The project aims will be achieved by combining innovative microwave technology, featuring multi-mode antennas and novel processing and imaging algor ....Microwave Detection of Structural Degradation in Maritime Industry. Novel applications of microwave technology to inspection systems in marine infrastructure will transform industry practice. By utilizing multi-mode antennas, the project aims to develop a gold-standard in microwave inspection, delivering more accurate and early detection of defects. The project aims will be achieved by combining innovative microwave technology, featuring multi-mode antennas and novel processing and imaging algorithms, with ground-breaking smart scanning and unmanned marine vehicle implementations. This innovative outcome obviates the need for current industry approaches based on inaccurate and tedious manual inspections, yielding massive cost savings and reductions in hazard associated with unanticipated structural failure.Read moreRead less
Transceive Phased Arrays for Parallel Imaging in High Field Magnetic Resonance Microscopy. This project will contribute to the development of a new generation of Magnetic Resonance Imaging systems that provide new and innovative features capable of significantly increasing the resolution and /or speed of imaging. The economic benefit of being a developer of this technology is clear and significant. These new systems will enhance the efficiency and power of clinical diagnostic testing. Specifica ....Transceive Phased Arrays for Parallel Imaging in High Field Magnetic Resonance Microscopy. This project will contribute to the development of a new generation of Magnetic Resonance Imaging systems that provide new and innovative features capable of significantly increasing the resolution and /or speed of imaging. The economic benefit of being a developer of this technology is clear and significant. These new systems will enhance the efficiency and power of clinical diagnostic testing. Specifically, the enabling of molecular imaging will enhance the study of many more disease states and rapid assessment of new in vivo therapeutic agents. The side-stream benefit to biomedical research and development in Australia is therefore substantial. Read moreRead less
A Wearable Motion Analysis System: Novel Clinical and Research Applications. Because the biomechanical analysis of human motion is confined to the laboratory, it often has restricted applicability. This is a recognized limitation, because laboratory studies cannot capture the true picture of how individuals move under conditions encountered during daily living. Consequently there are many situations where a more complete and realistic knowledge of biomechanics would be significant advantage such ....A Wearable Motion Analysis System: Novel Clinical and Research Applications. Because the biomechanical analysis of human motion is confined to the laboratory, it often has restricted applicability. This is a recognized limitation, because laboratory studies cannot capture the true picture of how individuals move under conditions encountered during daily living. Consequently there are many situations where a more complete and realistic knowledge of biomechanics would be significant advantage such as in the diagnosis, treatment and rehabilitation of movement disorders and injuries. The research project described in this proposal would for the first time, obtain comprehensive biomechanical data outside the laboratory using a fully integrated wearable motion analysis system.Read moreRead less