Caring For The Carer: Improving Self-efficacy To Provide Care And Reducing Anxiety Among Family Carers Of Primary Brain Tumour Patients
Funder
National Health and Medical Research Council
Funding Amount
$318,669.00
Summary
This fellowship will aim to improve self-efficacy and reduce anxiety among carers of primary brain tumour patients, who experience a significant burden due to their caregiving roles. This will be achieved through: (1) development of an online psychoeducational intervention; (2) pilot testing of the intervention; and (3) a randomised controlled trial of the intervention to determine its efficacy.
Exploring The Pluridimensionality Of Drug Efficacy.
Funder
National Health and Medical Research Council
Funding Amount
$326,184.00
Summary
Dysfunction of cell surface receptors is the underlying cause of many pathological conditions. Using cell based screening methods we aim to investigate the mechanisms underlying drug action, to understand how drugs acting at common targets promote distinct biological responses. This will aid the development of new therapeutics based on the ability to predict specific drug effects.
An Investigation Of The Involvement Of Clotting Factors In Abdominal Aortic Aneurysm (AAA) Progression Within A Mouse Model
Funder
National Health and Medical Research Council
Funding Amount
$189,401.00
Summary
Early stage weakening of the main abdominal artery is present in ~100,000 Australians and currently has no accepted therapy. Development of drug therapies which limit progression of the weakening process is urgently needed. In this study involvement of the clotting cascade in artery weakening will be investigated. The study have been planned in order to identify new strategies which can be developed as treatments for artery weakening in patients.
Applying Active Hospital-based Case Ascertainment To Assess Vaccine Effectiveness And Safety
Funder
National Health and Medical Research Council
Funding Amount
$258,741.00
Summary
Australia makes a considerable investment in vaccination, and the public are entitled to expect that vaccines are both safe and effective. The growing complexity of the vaccine schedule requires the development of new and flexible systems to monitor vaccine performance. This project aims to do this using surveillance nurses embedded in children's hospitals to actively find cases of diseases which are potentially vaccine-preventable as well as those which might have occurred as a side effect of v ....Australia makes a considerable investment in vaccination, and the public are entitled to expect that vaccines are both safe and effective. The growing complexity of the vaccine schedule requires the development of new and flexible systems to monitor vaccine performance. This project aims to do this using surveillance nurses embedded in children's hospitals to actively find cases of diseases which are potentially vaccine-preventable as well as those which might have occurred as a side effect of vaccination.Read moreRead less
Dissecting The Mechanisms Of Vaccine Immunogenicity And Induction Of Protective Immunity Against Influenza Virus
Funder
National Health and Medical Research Council
Funding Amount
$365,145.00
Summary
Influenza pandemics have historically led to worldwide morbidity and mortality. Vaccination remains to be the only plausible strategy to limit widespread mortality as a result of an influenza pandemic. The parts of the immune system important in protecting individuals from influenza virus are poorly understood. This research aims to understand the important correlates of protective immunity in order to improve vaccine design.
Strengthening Social And Emotional Wellbeing Of Australian Aboriginal People
Funder
National Health and Medical Research Council
Funding Amount
$292,639.00
Summary
The primary aim of this project is to strengthen Aboriginal people's wellbeing by understanding the development of their racial identity and related self-esteem and how these mediate mental wellbeing.
Discovering Molecular Signatures Of Human T Follicular Helper Cells And Antibody Producing B Cells To Improve Vaccine Efficacy And Transplation Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$408,768.00
Summary
A key way the body can fight off infections is to produce antibodies, a process that requires the coordinated efforts of multiple types of specialised immune cells. A more detailed understanding the factors that govern robust antibody responses is critically needed and will be investigated in this project in the context of vaccination and transplant rejection.