Industrial Transformation Research Hubs - Grant ID: IH210100040
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this ....ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this Hub include advanced manufacturing capacity for connected sensors, strategic partnerships and commercialisation skills to translate sensors research to create economic benefits such as jobs and locally-made products for domestic and export markets, as well as improving the health of Australians.Read moreRead less
Developing an integrated device for on-farm detection of sugarcane diseases. Pathogenic organisms cause yield losses of more than $150M pa to the Australian sugarcane industry and many millions more worldwide. Partnering with Sugar Research Australia, this project aims to develop a novel on-farm diagnostic device, comprising new nanotechnology and magnetism-induced microfluidics with naked eye observation and electrochemical detection. This device is expected to enable improved disease managemen ....Developing an integrated device for on-farm detection of sugarcane diseases. Pathogenic organisms cause yield losses of more than $150M pa to the Australian sugarcane industry and many millions more worldwide. Partnering with Sugar Research Australia, this project aims to develop a novel on-farm diagnostic device, comprising new nanotechnology and magnetism-induced microfluidics with naked eye observation and electrochemical detection. This device is expected to enable improved disease management strategies through the prediction of potential risks and rapid and effective actions to mitigate impending yield loss. In turn productivity and sustainability of Australia’s sugar industry will be enhanced. The new platform device has great potential for improved disease management in other crops in Australia and globally.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC210100056
Funder
Australian Research Council
Funding Amount
$3,975,864.00
Summary
ARC Training Centre for Next-Gen Technologies in Biomedical Analysis . The Centre for Next-Gen Technologies in Biomedical Analysis will deliver workforce trained in the development of transformative technologies that will rapidly expand the Australian pharmaceutical, diagnostic and defence sector. The university-industry partnership will increase Australia’s manufacturing capability by fast tracking screening, by integrating 3D printing, advanced sensing, big data analytics, machine learning an ....ARC Training Centre for Next-Gen Technologies in Biomedical Analysis . The Centre for Next-Gen Technologies in Biomedical Analysis will deliver workforce trained in the development of transformative technologies that will rapidly expand the Australian pharmaceutical, diagnostic and defence sector. The university-industry partnership will increase Australia’s manufacturing capability by fast tracking screening, by integrating 3D printing, advanced sensing, big data analytics, machine learning and artificial intelligence for the delivery of optimal solutions in diagnosis, treatment and wellbeing. The centre will deliver training in Industry 4.0 skills which will boost early-stage scale-up and accelerate the sector’s supply chain, which is pivotal for the Australian industries to maintain a competitive edge. Read moreRead less
Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipi ....Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipitation platform technology for making drug-core polymer-shell nanoparticles, and a new bio-inspired approach for making hybrid drug-core silica-shell nanocomposites, and new materials for applications in programmed release and delivery systems.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100502
Funder
Australian Research Council
Funding Amount
$424,875.00
Summary
Building Molecular Complexity Through Enzyme-Enabled Synthesis. Many valuable natural molecules are too complex to be commercially synthesised by current technologies. Despite advances in synthetic chemistry there is great need to adopt the elegant biocatalytic strategies for complex molecule synthesis found in nature, employing sophisticated enzyme catalysts. This interdisciplinary research program aims to address the shortcomings of traditional synthetic methods through the development of enzy ....Building Molecular Complexity Through Enzyme-Enabled Synthesis. Many valuable natural molecules are too complex to be commercially synthesised by current technologies. Despite advances in synthetic chemistry there is great need to adopt the elegant biocatalytic strategies for complex molecule synthesis found in nature, employing sophisticated enzyme catalysts. This interdisciplinary research program aims to address the shortcomings of traditional synthetic methods through the development of enzyme catalysts to rapidly generate complex molecular structures. These novel molecules can be readily converted into pharmaceuticals and agrochemicals leading to advancements in the bio-enabled production and application of organic molecules in these vital fields. Read moreRead less
Mechanical modulation of particle-cell interactions. Mechanical forces play critical roles in many biological processes, but how particle mechanical properties modulate particle-cell interactions remains elusive. This project aims to develop new design principles for engineering nano/micromaterials with tunable mechanical properties for improved cell activation and expansion, and to advance knowledge of the role of particle stiffness in modulating receptor-mediated particle-cell interactions. Ex ....Mechanical modulation of particle-cell interactions. Mechanical forces play critical roles in many biological processes, but how particle mechanical properties modulate particle-cell interactions remains elusive. This project aims to develop new design principles for engineering nano/micromaterials with tunable mechanical properties for improved cell activation and expansion, and to advance knowledge of the role of particle stiffness in modulating receptor-mediated particle-cell interactions. Expected outcomes and benefits include new fundamental understanding of the effect of particle mechanical properties on cell function, new insights into T cell activation and expansion, and new classes of stiffness-tunable fit-for-purpose materials for various applications in cell manufacturing.Read moreRead less
Catalytic Degardation of Emerging Microplastic Pollutants. This project aims to develop robust and low-cost nanocarbon hybrids and advanced remediation technology to address globally emerging microplastic contaminations. The project expects to boost innovations in development of novel magnetic nanomaterials, process of microplastic purification, and green catalysis. Expected outcomes of this project will include efficient strategies in materials fabrication and a cutting-edge nanotechnology. The ....Catalytic Degardation of Emerging Microplastic Pollutants. This project aims to develop robust and low-cost nanocarbon hybrids and advanced remediation technology to address globally emerging microplastic contaminations. The project expects to boost innovations in development of novel magnetic nanomaterials, process of microplastic purification, and green catalysis. Expected outcomes of this project will include efficient strategies in materials fabrication and a cutting-edge nanotechnology. The success of the project will underpin the scientific bases of carbocatalysis, provide significant benefits to the Australian industry and society for a sustainable future with clean water, and increase the leading capacity of Australia in fundamental research and frontier technology.Read moreRead less
New biocatalysts for selective chemical oxidations under extreme conditions. This project will identify and design new enzyme biocatalysts which function under extreme conditions such as elevated temperature and high concentrations of peroxides. These enzymes will be sourced from microorganisms which are located in extreme biological environments e.g. hot springs (the so-called extremophiles). The expected outcome of this project are the identification of robust enzymes which can catalyse select ....New biocatalysts for selective chemical oxidations under extreme conditions. This project will identify and design new enzyme biocatalysts which function under extreme conditions such as elevated temperature and high concentrations of peroxides. These enzymes will be sourced from microorganisms which are located in extreme biological environments e.g. hot springs (the so-called extremophiles). The expected outcome of this project are the identification of robust enzymes which can catalyse selective oxidation reactions in complex organic molecules, such as steroids. The new biocatalysts developed in this project will have significant benefit in the development of new routes to access bespoke molecules of value in fine chemical synthesis and drug development.
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Nanofluid stickiness will transform the Energy and Biotechnology Industries. This project aims to determine how minuscule particles behave on surfaces with different nano-architecture. Modern technologies already use nanodecorated materials to lubricate engines or capture tumour cells. Yet, their potential in applications for sustainable catalysis, gas treatment or water splitting cannot be realised until we understand how nano-objects adsorb to surfaces with features of comparable size. The exp ....Nanofluid stickiness will transform the Energy and Biotechnology Industries. This project aims to determine how minuscule particles behave on surfaces with different nano-architecture. Modern technologies already use nanodecorated materials to lubricate engines or capture tumour cells. Yet, their potential in applications for sustainable catalysis, gas treatment or water splitting cannot be realised until we understand how nano-objects adsorb to surfaces with features of comparable size. The expected outcomes include new methods, models and a workable map of protein adsorption allowing us to 1) create advanced substrates for targeted applications and 2) understand existing phenomenon governed by naturally occurring nanoroughness. It will benefit manufacturing in fields ranging from biology to energy production.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE210100253
Funder
Australian Research Council
Funding Amount
$450,948.00
Summary
Functional carbon hybrids for green catalysis and clean water. This project aims to develop a family of structure-tailored, robust and metal-free carbon hybrids and environmental-benign processes for catalytic degradation of emerging microcontaminants in water. Innovations are expected in the design of reaction-oriented nanocarbons, new concept in atomic level carbocatalysis from computation and in-situ characterisation, advanced purification technology, and breakthroughs in material engineering ....Functional carbon hybrids for green catalysis and clean water. This project aims to develop a family of structure-tailored, robust and metal-free carbon hybrids and environmental-benign processes for catalytic degradation of emerging microcontaminants in water. Innovations are expected in the design of reaction-oriented nanocarbons, new concept in atomic level carbocatalysis from computation and in-situ characterisation, advanced purification technology, and breakthroughs in material engineering. The anticipated outcomes will be the scientific basis for functional nanomaterials, nanotechnology, and green remediation technologies. Success will provide significant benefits in securing a sustainable future for Australia, with clean water and strategies for advanced manufacturing in related areas. Read moreRead less