High specificity nanosensors for glycobiology . This project aims to develop high specificity glycosensors for identifying and characterising carbohydrates. These glycosensors are expected to generate detailed information on carbohydrate stereochemical structure and how this controls protein-carbohydrate binding and other interactions fundamental to biochemical processes. This innovative nanotechnology aims to deliver a new capability for understanding cellular recognition and antigen binding me ....High specificity nanosensors for glycobiology . This project aims to develop high specificity glycosensors for identifying and characterising carbohydrates. These glycosensors are expected to generate detailed information on carbohydrate stereochemical structure and how this controls protein-carbohydrate binding and other interactions fundamental to biochemical processes. This innovative nanotechnology aims to deliver a new capability for understanding cellular recognition and antigen binding mechanisms. The expected outcomes are new tools for glycobiology and research into carbohydrate structure-function relationships, strengthening Australia’s global reputation in nanosensors with an incisive analytical technology for biomedical sciences and the many industries utilising carbohydrates.Read moreRead less
Multi-Colour Electrogenerated Chemiluminescence. This project plans to explore a new approach to chemical detection, in which molecules that emit different coloured light can be selectively switched on or switched off via the applied electrode potential. This would enable unprecedented numbers of simultaneous (multiplexed) detection events for time-critical analytical applications such as clinical diagnostics, environmental monitoring and biodefense assays. These assays could be performed on low ....Multi-Colour Electrogenerated Chemiluminescence. This project plans to explore a new approach to chemical detection, in which molecules that emit different coloured light can be selectively switched on or switched off via the applied electrode potential. This would enable unprecedented numbers of simultaneous (multiplexed) detection events for time-critical analytical applications such as clinical diagnostics, environmental monitoring and biodefense assays. These assays could be performed on low-cost microfluidic platforms operated by portable consumer devices such as mobile phones. Expected outcomes may provide new capabilities in rapid screening for disease biomarkers, environmental pollutants and bioterrorism agents, using simple, low-cost, portable instrumentation.Read moreRead less
New biosensing strategies based on bipolar electrochemiluminescence. Chemical analysis is a vital activity in our society, which is to a large extent confined to scientific laboratories and carried out with complex instrumentation. The breakthrough technology envisioned in this proposal will pave the way for simple, low-cost tests which can be used by non-scientists. The development of small, portable sensors for applications ranging from pollution monitoring to health testing, will enable ordi ....New biosensing strategies based on bipolar electrochemiluminescence. Chemical analysis is a vital activity in our society, which is to a large extent confined to scientific laboratories and carried out with complex instrumentation. The breakthrough technology envisioned in this proposal will pave the way for simple, low-cost tests which can be used by non-scientists. The development of small, portable sensors for applications ranging from pollution monitoring to health testing, will enable ordinary people to gain knowledge about the concentrations of molecular compounds in their environments and in themselves. This will stimulate economic and social benefits related to environmental testing and early disease diagnosis and generate new commercial opportunities for the Australian biotechnology industry.Read moreRead less
Microfluidic Separation Science: Innovative Technology for Characterising Complex Chemical Systems. At present there is a need for fast and detailed chemical analysis of complex samples, such as those important to biomedical diagnostics and forensic science. Innovative technology will be developed here in order to reduce analysis time whilst maintaining the integrity of the chemical information contained within the sample. This step change in separation science will directly aid biomedical diagn ....Microfluidic Separation Science: Innovative Technology for Characterising Complex Chemical Systems. At present there is a need for fast and detailed chemical analysis of complex samples, such as those important to biomedical diagnostics and forensic science. Innovative technology will be developed here in order to reduce analysis time whilst maintaining the integrity of the chemical information contained within the sample. This step change in separation science will directly aid biomedical diagnostics, forensic sample determination and industrial process monitoring through decreased analysis time with an increase in the chemical information gained. By performing chemical separations on a microfluidic scale a reduction in both the cost of analysis and impact of solvent waste on the environment will be achieved.Read moreRead less
Integration of DNA switches into wearables for smart chemical monitoring. This project addresses the scientific challenge of real-time monitoring of dynamic biological changes in the secretions found in sweat. By creating a wearable wireless device to monitor chemicals which interests Nutromics, using a novel electronic skin technology platform, the work aims to generate new knowledge of physiological changes in sweat secretions. Lying at the interface of analytical chemistry, functional materia ....Integration of DNA switches into wearables for smart chemical monitoring. This project addresses the scientific challenge of real-time monitoring of dynamic biological changes in the secretions found in sweat. By creating a wearable wireless device to monitor chemicals which interests Nutromics, using a novel electronic skin technology platform, the work aims to generate new knowledge of physiological changes in sweat secretions. Lying at the interface of analytical chemistry, functional materials and biomedical engineering, the project will contribute to the training of young researchers in these emerging technologies which interest Nutromics Pty Ltd. The project will improve Australia's standing in technology around wearable devices, improving our global competitive edge with economic and scientific impact.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100040
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this ....ARC RESEARCH HUB FOR CONNECTED SENSORS FOR HEALTH. This Hub aims to develop, manufacture and deploy high-tech, cyber-secure, medically-certified IoT sensors to global health markets by integrating disparate Australian capabilities into a productive end-to-end value chain. This Hub expects to position Australia at the forefront of connected health by integrating sensor science with cyber-secure data analytics, regulatory approval and certified manufacturing capabilities. Expected outcomes of this Hub include advanced manufacturing capacity for connected sensors, strategic partnerships and commercialisation skills to translate sensors research to create economic benefits such as jobs and locally-made products for domestic and export markets, as well as improving the health of Australians.Read moreRead less
Electrochemically-sensitized luminescence: A new bio-detection paradigm. This project aims to create new science which will enable the development of a superior new class of bio-detection technique, suitable for medical diagnostics and other sensing applications. A multi-disciplinary approach will be taken, combining expertise in a number of fields to explore the use of electrical rather than traditional optical means to control energy transfer and luminescence in novel molecular and nanoparticl ....Electrochemically-sensitized luminescence: A new bio-detection paradigm. This project aims to create new science which will enable the development of a superior new class of bio-detection technique, suitable for medical diagnostics and other sensing applications. A multi-disciplinary approach will be taken, combining expertise in a number of fields to explore the use of electrical rather than traditional optical means to control energy transfer and luminescence in novel molecular and nanoparticle-based systems. It is expected that these advances will transform bio-analytical science by giving rise to innovative detection techniques which are low-cost, rapid and highly sensitive.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC140100022
Funder
Australian Research Council
Funding Amount
$2,148,935.00
Summary
ARC Training Centre for Portable Analytical Separation Technologies. ARC Training Centre for Portable Analytical Separation Technologies. Portable analytical separation systems will enable point-of sample analysis for complex samples in food, environmental and clinical applications. The Training Centre aims to train the next generation of industry-ready Australian researchers through creating a sustainable research partnership between university-based researchers and Australian industry focused ....ARC Training Centre for Portable Analytical Separation Technologies. ARC Training Centre for Portable Analytical Separation Technologies. Portable analytical separation systems will enable point-of sample analysis for complex samples in food, environmental and clinical applications. The Training Centre aims to train the next generation of industry-ready Australian researchers through creating a sustainable research partnership between university-based researchers and Australian industry focused on developing new capabilities and technologies that have the potential to facilitate, support, or catalyse the progressive deployment of portable separation science technologies into society. This will enable the development of new, portable and affordable analytical separation systems and contribute to creating a sustainable, globally competitive manufacturing industry in Australia.Read moreRead less
Integration of crystal engineering and electrochemistry: tuneable multifunctional organic-inorganic hybrid materials with redox capability. Multi-dimensional technologically important materials containing organic redox activity and organic, inorganic or biologically important functionality will be rationally synthesised. Scientists from different backgrounds will exploit opportunities for applied research outcomes derived from advances achieved in chemical, biological and materials sciences.
Industrial Transformation Training Centres - Grant ID: IC140100023
Funder
Australian Research Council
Funding Amount
$1,800,000.00
Summary
ARC Training Centre in Biodevices. ARC Training Centre in Biodevices. The Training Centre aims to assist Australian biodevice and diagnostics companies to develop the next generation of innovative and profitable products that address important healthcare needs in our communities. This will be achieved by addressing industry-specific challenges relating to the multidisciplinary nature of design and development in the biodevices and diagnostics sector; technology uptake and transfer to manufacturi ....ARC Training Centre in Biodevices. ARC Training Centre in Biodevices. The Training Centre aims to assist Australian biodevice and diagnostics companies to develop the next generation of innovative and profitable products that address important healthcare needs in our communities. This will be achieved by addressing industry-specific challenges relating to the multidisciplinary nature of design and development in the biodevices and diagnostics sector; technology uptake and transfer to manufacturing; the composition, maturity and size of local firms in the sector; and the development of high-level entrepreneurial skills for innovative industry researchers. The Training Centre will remove barriers to collaboration between universities and industry by delivering exceptional return on research investment.Read moreRead less