Discovery Early Career Researcher Award - Grant ID: DE140101056
Funder
Australian Research Council
Funding Amount
$380,156.00
Summary
Rational Design of Plasmonic Nanoassemblies for Rapid and Multiplexed Point-of-Care Diagnosis by Surface-enhanced Raman Spectroscopy (SERS). The central aim of this project is to develop a novel technology/sensor platform for rapid, quantitative, multiplexed and highly sensitive point-of-care diagnostics using surface-enhanced Raman spectroscopy (SERS) as the read-out approach. Three-dimensional plasmonic superstructures as novel SERS labels will be synthesised and characterised at single-partic ....Rational Design of Plasmonic Nanoassemblies for Rapid and Multiplexed Point-of-Care Diagnosis by Surface-enhanced Raman Spectroscopy (SERS). The central aim of this project is to develop a novel technology/sensor platform for rapid, quantitative, multiplexed and highly sensitive point-of-care diagnostics using surface-enhanced Raman spectroscopy (SERS) as the read-out approach. Three-dimensional plasmonic superstructures as novel SERS labels will be synthesised and characterised at single-particle level and the choice of optimal SERS-active three-dimensional superstructures for use will be guided by empirical structure-activity correlations in combination with computer simulations. Tumour biomarkers for breast cancer will be employed as the model target for establishing the detection platform in a portable configuration for point-of-care diagnostics.Read moreRead less
A highly sensitive and selective nano-engineered sensor for the online monitoring of mercury vapour emissions from harsh industrial processes. The Australian alumina and aluminium industries contribute over $11 billion export income annually. All refineries, except one, operate in rural areas and are the main economic drivers in these regions. In order to maintain the industry's commitment to reduce the environmental impact of its processes and remain economically sustainable, innovative technol ....A highly sensitive and selective nano-engineered sensor for the online monitoring of mercury vapour emissions from harsh industrial processes. The Australian alumina and aluminium industries contribute over $11 billion export income annually. All refineries, except one, operate in rural areas and are the main economic drivers in these regions. In order to maintain the industry's commitment to reduce the environmental impact of its processes and remain economically sustainable, innovative technologies are required to monitor mercury emissions. The aim of this project is to develop robust sensors, for online monitoring of mercury vapours, that operate under challenging industrial environments. This project will also provide excellent training for young researchers in established international industrial research groups, thereby meeting skill shortages in the Australian resource sector.Read moreRead less
Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanopart ....Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanoparticles with well-defined light absorption properties will be fabricated. Superior selectivity will be achieved by matching the wavelength of the absorbed light with the required activation energy for oxidation/reduction. Successful outcomes will enable multi-analyte fingerprint identification by on-chip devices with applications ranging from portable medical diagnostics to national security.Read moreRead less
Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipi ....Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipitation platform technology for making drug-core polymer-shell nanoparticles, and a new bio-inspired approach for making hybrid drug-core silica-shell nanocomposites, and new materials for applications in programmed release and delivery systems.Read moreRead less
Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microflu ....Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microfluidic platform technology for reproducibly producing targeted polymer nanocarriers having systematically varied properties, a dual-templating method for making targeted silica nanocapsules and new design of in vivo-mimicking 'Tissue Chips' for screening and evaluating the nanocarriers.Read moreRead less
Next generation core-shell materials based on biomolecular dual-templating. This project aims to discover and develop new methods and knowledge for the precision engineering of next-generation core-shell materials using sustainable biomolecular dual-templating processes. This research builds on a recent breakthrough - emulsion and biomimetic dual-templating technology for facile preparation of silica capsules, and is expected to revolutionise current approaches for making core-shell materials. S ....Next generation core-shell materials based on biomolecular dual-templating. This project aims to discover and develop new methods and knowledge for the precision engineering of next-generation core-shell materials using sustainable biomolecular dual-templating processes. This research builds on a recent breakthrough - emulsion and biomimetic dual-templating technology for facile preparation of silica capsules, and is expected to revolutionise current approaches for making core-shell materials. Significant outcomes are expected to be achieved through building fundamental understanding around this breakthrough, including new concepts for hierarchical nanomaterials based on biomolecular design, new molecular and engineering design rules for core-shell materials, and novel materials for applications in sustained release and delivery systems.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180101190
Funder
Australian Research Council
Funding Amount
$359,446.00
Summary
Interfacial nano-engineering of electrodes for perovskite solar cells. This project aims to explore new strategies of functional electrode design and interfacial engineering for efficient and stable perovskite solar cell application. The key concept is to modify the electron transport and perovskite layers through structural design, interfacial engineering and contact passivation, for use in high-performance solar-to-electricity conversion systems with improved light harvesting and charge collec ....Interfacial nano-engineering of electrodes for perovskite solar cells. This project aims to explore new strategies of functional electrode design and interfacial engineering for efficient and stable perovskite solar cell application. The key concept is to modify the electron transport and perovskite layers through structural design, interfacial engineering and contact passivation, for use in high-performance solar-to-electricity conversion systems with improved light harvesting and charge collection. Expected project outcomes will place Australia at the forefront of practical low-cost and large-scale solar energy conversion technologies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200101244
Funder
Australian Research Council
Funding Amount
$417,276.00
Summary
Advanced zinc-ion batteries with high voltage and high energy density. Zinc-ion battery is not only cheaper than current lithium-ion battery (LIB), but it is safer due to a neutral aqueous electrolyte. However, its grid-scale development is plagued by limited output voltage and inadequate energy density compared with more mainstream LIB. This project aims to solve the discharge-voltage problem by fabricating atomic-level structure engineered manganese (Mn)-based cathode and a new stable solid-st ....Advanced zinc-ion batteries with high voltage and high energy density. Zinc-ion battery is not only cheaper than current lithium-ion battery (LIB), but it is safer due to a neutral aqueous electrolyte. However, its grid-scale development is plagued by limited output voltage and inadequate energy density compared with more mainstream LIB. This project aims to solve the discharge-voltage problem by fabricating atomic-level structure engineered manganese (Mn)-based cathode and a new stable solid-state electrolyte, and improve the device energy density by zinc (Zn) anode interface nanotechnology. The success of this project will benefit Australia’s access to new markets and introduce a new low-cost and safe energy storage technology for the long-term viability of Australia’s abundant Zn and Mn resources.Read moreRead less
Photochemical toolkit based on tetracyanoquinodimethane metal-organic semiconducting hybrids. This project aims to develop low-cost light-activated materials for flexible electronics, wearable sensors, antimicrobial fabrics and highly active catalysts. A photochemical toolkit will be developed comprising ultraviolet-active zinc oxide, visible-active metals and visible/infrared-active charge transfer semiconducting materials. Hybridisation of these components will create materials photoactive acr ....Photochemical toolkit based on tetracyanoquinodimethane metal-organic semiconducting hybrids. This project aims to develop low-cost light-activated materials for flexible electronics, wearable sensors, antimicrobial fabrics and highly active catalysts. A photochemical toolkit will be developed comprising ultraviolet-active zinc oxide, visible-active metals and visible/infrared-active charge transfer semiconducting materials. Hybridisation of these components will create materials photoactive across the solar spectrum, leading to photo-redox catalysis and light-activated antimicrobial applications. These materials are expected to lead to cost-effective industrial processes, efficient environmental monitoring, clean-up of industrially-contaminated water streams, infection control in wounds and healthcare settings, and advancing consumer technology platforms.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100892
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Designing compressible hybrid supercapacitors from graphene aerogels. This project aims to develop high-performance compressible energy storage devices. Compressible hybrid supercapacitors are promising energy storage devices for elastic and wearable electronics under large strain and deformation. However, the controlled fabrication of such devices is challenging. This project aims to design and synthesise compressible hybrid supercapacitors using graphene aerogels as substrates through structur ....Designing compressible hybrid supercapacitors from graphene aerogels. This project aims to develop high-performance compressible energy storage devices. Compressible hybrid supercapacitors are promising energy storage devices for elastic and wearable electronics under large strain and deformation. However, the controlled fabrication of such devices is challenging. This project aims to design and synthesise compressible hybrid supercapacitors using graphene aerogels as substrates through structural design and surface modification. The success of the project will benefit Australia’s booming graphite industry and promote Australian competitiveness in wearable electronics markets.Read moreRead less