Engineered plant receptors as orthogonal neuronal switches. This project aims to develop synthetic biology methods to study brain function by utilising engineered plant receptors. This project will expand our ability to manipulate nerve cell function with high specificity and without side effects in freely behaving animals. Plant receptors will be developed into molecular tools in an iterative process that improves key properties using rational protein design. Expected outcomes include innovativ ....Engineered plant receptors as orthogonal neuronal switches. This project aims to develop synthetic biology methods to study brain function by utilising engineered plant receptors. This project will expand our ability to manipulate nerve cell function with high specificity and without side effects in freely behaving animals. Plant receptors will be developed into molecular tools in an iterative process that improves key properties using rational protein design. Expected outcomes include innovative and broadly-applicable neuroscience methods and an understanding of receptors involved in plant growth and defense. Benefits of this project include an enhanced capacity to generate knowledge, multidisciplinary training opportunities and patentable synthetic biology technologies.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100030
Funder
Australian Research Council
Funding Amount
$4,133,659.00
Summary
ARC Training Centre in Cognitive Computing for Medical Technologies. The ARC Training Centre in Cognitive Computing for Medical Technologies aims to create a workforce that is expert in developing, applying and interrogating cognitive computing technologies in data-intensive medical contexts. This will facilitate the next generation of data-driven and machine learning-based medical technologies. The Centre will provide a world-class industry-driven research training environment for PhD students ....ARC Training Centre in Cognitive Computing for Medical Technologies. The ARC Training Centre in Cognitive Computing for Medical Technologies aims to create a workforce that is expert in developing, applying and interrogating cognitive computing technologies in data-intensive medical contexts. This will facilitate the next generation of data-driven and machine learning-based medical technologies. The Centre will provide a world-class industry-driven research training environment for PhD students and postdoctoral researchers. These researchers will lead the medical technology industry into a new era of data-driven personalised and precision medical devices and applications. The Centre will result in the development of capabilities in the core technologies of machine learning and the practical application of cognitive computing in the area of health.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100190
Funder
Australian Research Council
Funding Amount
$620,000.00
Summary
Electrophysiology Platform for Ion-channel Characterisation. Ion channels are ubiquitous pore-forming membrane proteins, with the human genome encoding >300 ion channels. The diverse roles of ion channels include action potential generation, control of ion flow across secretory and epithelial cells, and regulation of cell volume, motility and proliferation. Pharmacological modulators are powerful tools for probing ion channel function, but for most channels these tools are lacking. Thus, this p .... Electrophysiology Platform for Ion-channel Characterisation. Ion channels are ubiquitous pore-forming membrane proteins, with the human genome encoding >300 ion channels. The diverse roles of ion channels include action potential generation, control of ion flow across secretory and epithelial cells, and regulation of cell volume, motility and proliferation. Pharmacological modulators are powerful tools for probing ion channel function, but for most channels these tools are lacking. Thus, this project aims to develop the first comprehensive toolbox of ion channel modulators using an integrated in vitro/in vivo electrophysiology platform. These pharmacological tools will be made freely available to the Australian research community for probing the mechanism and physiological function of ion channels.Read moreRead less
Creating perceptual experts in Australia's policing and security agencies. This project aims to create the next generation of experts in Australia’s policing and national security agencies, by improving crime scene evidence interpretation. Agencies are under pressure to develop more rigorous training practices that go beyond mere intuition and tradition. This project will use a novel approach that directs learning toward the most diagnostic perceptual cues. Expected outcomes include a solid empi ....Creating perceptual experts in Australia's policing and security agencies. This project aims to create the next generation of experts in Australia’s policing and national security agencies, by improving crime scene evidence interpretation. Agencies are under pressure to develop more rigorous training practices that go beyond mere intuition and tradition. This project will use a novel approach that directs learning toward the most diagnostic perceptual cues. Expected outcomes include a solid empirical basis for national training programs designed to create experts that are accurate, reliable, and continuously improving. Improving the training of experts will ensure the integrity of forensics as evidentiary tools available to police, lead to more reliable courtroom convictions and help safeguard Australia from terrorism and crime.Read moreRead less
Predicting the diagnostic performance of individuals and organisations. Predicting the diagnostic performance of individuals and organisations. This project aims to address diagnostic error in advanced technology systems, by providing a mechanism to assess and improve individual diagnosticians’ performance. Organisations that rely on their employees’ diagnostic skills rarely assess them once the operators become qualified, so there is no basis for interventions that might prevent diagnostic erro ....Predicting the diagnostic performance of individuals and organisations. Predicting the diagnostic performance of individuals and organisations. This project aims to address diagnostic error in advanced technology systems, by providing a mechanism to assess and improve individual diagnosticians’ performance. Organisations that rely on their employees’ diagnostic skills rarely assess them once the operators become qualified, so there is no basis for interventions that might prevent diagnostic errors affecting thousands. This research tests a new method of assessing diagnostic skills based on how skilled operators respond to cues. This project will test how employees’ diagnostic skills change and whether this change corresponds to measures of organisational performance. This research is expected to provide organisations with a tool to pre-empt diagnostic errors that could minimise costs to the economy.Read moreRead less
How tired is too tired? Determining the effects of fatigue on pilots' performance in a simulated flight environment. Increasingly, pilots are required to work more flexible flight schedules that expose them to greater levels of work-related fatigue. Consequently, a recent federal parliamentary inquiry recommended that a fatigue risk management approach be applied to the regulation of pilots? flight and duty times. A key aspect of such an approach, and the aim of the proposed project, is to det ....How tired is too tired? Determining the effects of fatigue on pilots' performance in a simulated flight environment. Increasingly, pilots are required to work more flexible flight schedules that expose them to greater levels of work-related fatigue. Consequently, a recent federal parliamentary inquiry recommended that a fatigue risk management approach be applied to the regulation of pilots? flight and duty times. A key aspect of such an approach, and the aim of the proposed project, is to determine the level of fatigue at which pilots? ability to operate an aircraft reaches a safety-critical level. This research will provide a scientifically validated benchmark for regulating pilots? flight and duty times. Ultimately, this will improve safety for the flying public.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100008
Funder
Australian Research Council
Funding Amount
$4,459,672.00
Summary
ARC Training Centre for Innovative Wine Production. The ARC Training Centre for Innovative Wine Production aims to tackle challenges to wine production through innovative, multi-disciplinary research. Australia’s grape and wine industry is a multi-billion dollar industry, yet in some areas profitability is low. Reasons include extreme weather events, soil salinity and diseases, inefficient practices, a low level of technological innovation and high input costs. New technologies and process effic ....ARC Training Centre for Innovative Wine Production. The ARC Training Centre for Innovative Wine Production aims to tackle challenges to wine production through innovative, multi-disciplinary research. Australia’s grape and wine industry is a multi-billion dollar industry, yet in some areas profitability is low. Reasons include extreme weather events, soil salinity and diseases, inefficient practices, a low level of technological innovation and high input costs. New technologies and process efficiencies developed as part of this project will reduce environmental impact, drive production costs down and profits and employment up. The project will mount a suite of industry-led projects to deliver outcomes to boost Australia’s competitiveness as a supplier of sustainably-produced premium branded wine to the world.Read moreRead less
Radicalisation, Counter-Radicalisation, and De-Radicalisation: Developing a New Understanding of Terrorism in the Australian Context. Concentrating on the unique drivers of extremism within Victoria (and Australia), the study will enhance counter terrorism stakeholders' understanding of domestic radicalization. This will assist in designing policies appropriate for Australian circumstances that can: 1. pre-empt, prevent and detect radicalisation without jeopardising social cohesion and 2. reduce ....Radicalisation, Counter-Radicalisation, and De-Radicalisation: Developing a New Understanding of Terrorism in the Australian Context. Concentrating on the unique drivers of extremism within Victoria (and Australia), the study will enhance counter terrorism stakeholders' understanding of domestic radicalization. This will assist in designing policies appropriate for Australian circumstances that can: 1. pre-empt, prevent and detect radicalisation without jeopardising social cohesion and 2. reduce Australia's reliance on overseas counter-radicalisation and de-radicalisation models, where practitioners confront different community dynamics. Working towards understanding what causes radicalization in Australia, the project offers to enhance national security and by addressing local circumstances carries the prospect of creating more cost-efficient counter terrorism practices.Read moreRead less
Sleeping for Gold: The Influence of Sleep on the Sports Performance of Elite Athletes. The aim of this project is to improve the performance of Australia's elite athletes by enhancing the amount and quality of sleep that they obtain. This project will have three major benefits. First, successful role models will encourage more Australian children and adults to participate in sport. This is critical given that the incidence of obesity (a major risk factor for diabetes, cardiovascular disease and ....Sleeping for Gold: The Influence of Sleep on the Sports Performance of Elite Athletes. The aim of this project is to improve the performance of Australia's elite athletes by enhancing the amount and quality of sleep that they obtain. This project will have three major benefits. First, successful role models will encourage more Australian children and adults to participate in sport. This is critical given that the incidence of obesity (a major risk factor for diabetes, cardiovascular disease and some cancers) has doubled in Australia in the last 15 years as participation in sport has dropped. Second, the success of our elite athletes will provide a source of pride in our achievements as a nation. Third, this research will enable the Australian Institute of Sport to remain as an international leader in sports science research.Read moreRead less