Understanding How Azithromycin Prevents Exacerbations In Severe Asthma
Funder
National Health and Medical Research Council
Funding Amount
$697,273.00
Summary
In some people with severe asthma, conventional inhaler treatments are not able to control the disease so there is a need for new treatment options. We have recently completed a large clinical trial which showed that very low doses of a common antibiotic help prevent asthma attacks in this situation. However, not much is known about how the antibiotic is working. This study will help us understand how the antibiotic is working and which people respond best.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100035
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Hyperpolarised gas functional lung and molecular imaging. This project will produce a polariser to generate magnetised gas for research with magnetic resonance imaging (MRI). This allows imaging of normal and abnormal lung ventilation and circulation in animal and humans. The use of these hyperpolarised gases can also be used to tag specific molecules and increase understanding of lung metabolism.
New Insights Into Viral Inflammatory Disease Mechanisms And Approaches To Therapy
Funder
National Health and Medical Research Council
Funding Amount
$631,010.00
Summary
This fellowship aims to establish how viruses cause disease, including how they evade the immune response to persist and cause disease for prolonged periods. My vision is that knowing how the virus and the immune system interact to determine disease severity will assist in devising new treatments and prevention programs to lessen the impact of viral diseases in Australia and worldwide.
Special Research Initiatives - Grant ID: SR0354576
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Spatially Integrated Social Science Research in Australia. Rapid change across society has resulted in shifts to the scope of social science research including the emergence of space and place as an important concept. Across research fields the result has been that a range of innovative and unique techniques, methodologies and theories that are space based are now being developed. While research is progressing rapidly, it is undertaken in parallel by researchers who can not always collaborate. ....Spatially Integrated Social Science Research in Australia. Rapid change across society has resulted in shifts to the scope of social science research including the emergence of space and place as an important concept. Across research fields the result has been that a range of innovative and unique techniques, methodologies and theories that are space based are now being developed. While research is progressing rapidly, it is undertaken in parallel by researchers who can not always collaborate. Recognising these advances, this initiative focuses on harnessing Australia's capacity and potential in the use of spatially based methods and theories and brings researchers together in collaboration across a number of fields. Read moreRead less
ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial ....ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial concepts into statistical analysis and modelling, powerful visualisation of information, and the building spatial decision support systems, to provide an improved evidence base and better informed decision-making to address the significant challenges facing Australia's people and its places.Read moreRead less
Special Research Initiatives - Grant ID: SR120300015
Funder
Australian Research Council
Funding Amount
$16,000,000.00
Summary
The Science of Learning Research Centre. In this innovative new Centre, researchers in education, neuroscience and cognitive psychology will work together with teachers to understand the learning process. This collaboration will establish new criteria to assess the impact of different types of learning and strategies to inform teaching practices of benefit to all Australians.
Unpacking the immune system with applied mathematics. This project aims to model immune interactions across cells and structures spanning scales of nanometres to millimetres. It expects to develop innovative mathematical insights, improve our understanding of immunology, and consolidate collaborations with top American and European laboratories and groups. Expected outcomes include cutting-edge techniques for multiscale biological modelling and improved prediction and analysis of immune dynami ....Unpacking the immune system with applied mathematics. This project aims to model immune interactions across cells and structures spanning scales of nanometres to millimetres. It expects to develop innovative mathematical insights, improve our understanding of immunology, and consolidate collaborations with top American and European laboratories and groups. Expected outcomes include cutting-edge techniques for multiscale biological modelling and improved prediction and analysis of immune dynamics. The project should provide benefits to industries where highly organised behaviours are important, for example those interested in robot swarming, optimal transportation, and epidemic management. It should also benefit Australian students and researchers with novel overseas training opportunities.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100168
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
Facility for Characterisation of BioNanomaterials. Facility for characterisation of bionanomaterials:
The facility for characterisation of bionanomaterials aims to provide researchers with access to an integrated facility for advanced characterisation of nanomaterials from inception to application in biomedicine. Nanotechnology has contributed to significant advances across a range of disciplines and is increasingly used in biomedical applications. The facility aims to allow detailed examinatio ....Facility for Characterisation of BioNanomaterials. Facility for characterisation of bionanomaterials:
The facility for characterisation of bionanomaterials aims to provide researchers with access to an integrated facility for advanced characterisation of nanomaterials from inception to application in biomedicine. Nanotechnology has contributed to significant advances across a range of disciplines and is increasingly used in biomedical applications. The facility aims to allow detailed examination of how nanomaterials interact in biological systems; from individual nanoparticles to whole animals, and through developing this fundamental understanding provide the means to produce new and highly effective nanomaterials for biomedical applications. The facility plans to support programs using nanomaterials for molecular imaging and intelligent drug delivery, while developing greater understanding of how to create more effective nanobiomaterials.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100156
Funder
Australian Research Council
Funding Amount
$289,500.00
Summary
3D Two-Photon Nanoprinter for Advanced Multi-Functional Materials & Devices. The Nanoscribe Photonic Professional GT2 Two-Photon 3D Printer enables tailoring materials’ architecture at nanoscale. This results in unique optical, mechanical, electrical, chemical, biochemical, and acoustic properties enabling a wealth of cutting-edge research activities in variety of fields including mechanical/optical/electrical metamaterials, bioinspired hard/soft materials, biomaterials (e.g., structured cell-ti ....3D Two-Photon Nanoprinter for Advanced Multi-Functional Materials & Devices. The Nanoscribe Photonic Professional GT2 Two-Photon 3D Printer enables tailoring materials’ architecture at nanoscale. This results in unique optical, mechanical, electrical, chemical, biochemical, and acoustic properties enabling a wealth of cutting-edge research activities in variety of fields including mechanical/optical/electrical metamaterials, bioinspired hard/soft materials, biomaterials (e.g., structured cell-tissue interfaces), biomedical devices (implantable devices and drug-delivery systems), nanofluidics, and photonic crystals. In each of these fields, we will use GT2 to print variety of polymers, hydrogels, metals and ceramics, for example by printing polymer-derived nanoceramics that will be simultaneously strong and tough.Read moreRead less
Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will re ....Engineering floating liquid marbles for three-dimensional cell cultures. This project aims to understand the physics of three-dimensional cell cultures in a liquid marble floating on a liquid free surface. New methodology developed can produce these cell cultures without using matrices or scaffolds and with run-times well beyond existing technologies. This methodology closely mimics a normal in-vivo environment and produces spheroids needed in cell transplantation therapies. This project will resolve uncertainties in the underlying phenomena. The expected outcome should support future high quality cell cultures suitable for transplantation therapies.Read moreRead less