Randomized Controlled Trial Of A Video-delivered Intervention For The Early Detection Of Melanoma In Men 50+ Years
Funder
National Health and Medical Research Council
Funding Amount
$511,694.00
Summary
Unfortunately, men over 50 years are most at risk to die from melanoma. Skin self-examination, where a man inspects the skin of his whole body with the help of a mirror or another person, and rapid presentation to a doctor without delay if he detects a suspicious lesion has the potential to increase awareness for the skin and to improve early diagnosis. We want to assess if we can increase the rate of skin self-examination in men 50 years and over through a video-delivered intervention.
Integrating Behaviour Change And Technology Uptake Models Into Skin Cancer Prevention And Early Detection
Funder
National Health and Medical Research Council
Funding Amount
$459,271.00
Summary
Two in three Australians will develop skin cancer in their lifetime, and skin cancer incidence is expected to increase. Therefore optimal ways to prevent and early detect skin cancers are of utmost importance to Australia’s public. By integrating the latest behaviour change models and technology uptake models to develop innovative interventions, this fellowship aims to ascertain that all Australians regardless of their location have access to optimal skin cancer prevention and early detection ca ....Two in three Australians will develop skin cancer in their lifetime, and skin cancer incidence is expected to increase. Therefore optimal ways to prevent and early detect skin cancers are of utmost importance to Australia’s public. By integrating the latest behaviour change models and technology uptake models to develop innovative interventions, this fellowship aims to ascertain that all Australians regardless of their location have access to optimal skin cancer prevention and early detection care.Read moreRead less
ShadePlus: A Built Environment Intervention To Improve Park Usage, Physical Activity, Sun Protection Behaviours And Mental Well-being Of Park Goers And Residents In Disadvantaged Neighbourhoods
Funder
National Health and Medical Research Council
Funding Amount
$430,292.00
Summary
This project will assess the effects of adding improved park amenities to promote increased park use, sun protection behaviours, physical activity and mental well-being among park goers and residents in disadvantaged suburbs in Melbourne. The study involving the park improvements are conducted in partnership with the Brimbank City Council form 2013 to 2015. It will use a natural experiment study design where measures of health related-outcomes are assessed before and after modifying the park env ....This project will assess the effects of adding improved park amenities to promote increased park use, sun protection behaviours, physical activity and mental well-being among park goers and residents in disadvantaged suburbs in Melbourne. The study involving the park improvements are conducted in partnership with the Brimbank City Council form 2013 to 2015. It will use a natural experiment study design where measures of health related-outcomes are assessed before and after modifying the park environment.Read moreRead less
Towards Global Control Of Scabies: Advances In Diagnosis, Treatment And Community Control
Funder
National Health and Medical Research Council
Funding Amount
$340,891.00
Summary
The scabies mite causes severe itch and rash and leads to infections, kidney and heart disease. Scabies affects up to 50% of children in Indigenous communities. We now know most scabies can be prevented, so we urgently need to find the most effective strategies. My research will develop new tests to help doctors to accurately diagnose scabies. I will test new medicines to treat scabies and strategies to prevent scabies and its complications in children, families and entire populations.
Effectiveness And Cost-effectiveness Of Systematic Screening For Lynch Syndrome (LS) In Australia
Funder
National Health and Medical Research Council
Funding Amount
$485,762.00
Summary
Lynch syndrome (LS) is an inherited condition that puts people at an increased risk of developing a range of cancers. We will use a detailed simulation model to evaluate the potential health benefits of testing new cases of colorectal, endometrial and ovarian cancers for LS, and whether this would be cost-effective. The aim is to identify LS-related cancer cases, so family members can be offered LS testing, and individuals found to have LS can be offered close observation/preventative surgery.
Assessment Of The Effects Of Pathogenic Germline TP53 Mutations; International Sarcoma Kindred Study Participants’ Views Of Feedback Of Genetic Research Results And The Acceptability Of Taking Part In A Pilot Screening Programme
Funder
National Health and Medical Research Council
Funding Amount
$55,242.00
Summary
The International Sarcoma Kindred Study (ISKS) aims to identify individuals who harbour germline TP53 mutations. TP53 mutations are characterised by the development of multiple cancers including sarcoma. This project will assess ISKS participants’ views of the feedback of genetic research information and will develop sensitive feedback practices. The acceptability and psychological impact of taking part in a pilot screening protocol designed for cancer-prone populations will also be assessed.
Re-participation In Screening For Colorectal Cancer: Behavioural Outcomes And Predictors.
Funder
National Health and Medical Research Council
Funding Amount
$687,438.00
Summary
Screening for bowel cancer (CRC) is an important public health initiative. It is most effective when undertaken regularly but there is little research on what personal factors relate to ongoing participation in a screening program. This study will determine the factors associated with ongoing participation in CRC screening and will lead to better screening programs and improved health benefits. This study directly addresses the Cancer Australia priority area re improving screening programs.
Green Tea Polyphenols And Cancer Prevention: Use Of Population Controls And Biomarkers To Elicit Causal Pathways
Funder
National Health and Medical Research Council
Funding Amount
$956,189.00
Summary
There is laboratory evidence that chemicals in green tea (poloyphenols) protect against cancer. Epidemiologic studies in humans have generally supported these findings, especially for breast cancer. This project is a crucial stepping stone towards future prospects of a large-scale trial using green tea extract. It will see if the protection extends to leukaemia and bowel cancer, and will identify the genetic makeup of people who are able to benefit the most from green tea polyphenols.
The Australian And New Zealand Diabetes And Cancer Collaboration
Funder
National Health and Medical Research Council
Funding Amount
$412,291.00
Summary
Diabetes, obesity, metabolic syndrome, hypertension and cancer are chronic diseases faced by many Australians. There is some evidence to suggest that those with diabetes or are obese are at an increased risk of cancer. Sufficiently large studies to examine these relationships do not exist in Australia. This project aims to pool Australian and New Zealand longitudinal studies which have information on diabetes and obesity to examine the relationship between diabetes, obesity and cancer.
Case-control Study Of Reasons For Presentation Of Nonmelanocytic Skin Cancers At An Advanced Stage.
Funder
National Health and Medical Research Council
Funding Amount
$250,614.00
Summary
There are about four times as many skin cancers treated in Australia each year as all other cancers combined and the vast majority of these are the nonmelanocytic skin cancers (NMSC). While most of these cancers are easily treatable, a proportion of these cancers are not given potentially effective treatment until the cancer has reached an advanced stage. Preliminary results from our pilot studies indicate that at least 50% of patients with NMSC who are treated with radiotherapy and 92% of NMSC ....There are about four times as many skin cancers treated in Australia each year as all other cancers combined and the vast majority of these are the nonmelanocytic skin cancers (NMSC). While most of these cancers are easily treatable, a proportion of these cancers are not given potentially effective treatment until the cancer has reached an advanced stage. Preliminary results from our pilot studies indicate that at least 50% of patients with NMSC who are treated with radiotherapy and 92% of NMSC patients treated with a graft or flap surgical procedure by the dermatologists in Newcastle are so treated because of the extent of disease at the primary site. These advanced stage cancers make an important contribution to the 70,000 admissions to hospital for the treatment of NMSC each year in Australia. The total direct health services cost of treatment of these skin cancers was estimated to be $232,000,000 in 1993-94, which was more than for any other type of cancer. Some 379 people died from nonmelanocytic skin cancer in Australia in 1993 and these were all potentially preventable deaths. The study aims are therefore to: 1. Measure the contributions of delay in seeking treatment and inadequate inital treatment to the need for treatment of skin cancer at an advanced stage. 2. Ascertain the factors that are associated with delay in seeking treatment for skin cancer until it has reached an advanced stage. This study will be the first substantial and population-based study of advanced skin cancer and the factors that underlie it. It will give the first empirical guidance to the design of initiatives to prevent the development of advanced skin cancer, a major area of cost to Australian health services. The study will increase understanding of why some skin cancers are not treated definitively until they reach an advanced stage and guide the development of interventions to reduce the frequency of patients who present with advanced stage skin cancer.Read moreRead less