Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882701
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Establishment of a confocal/multiphoton microscope for imaging of living systems. This facility will allow us to study the dynamic changes in living systems, from the smallest unicellular organisms in the ocean through to the sophisticated neural networks of the living brain. Not only will this imaging facility allow us to understand how living systems work, we will also be able to explore the dynamic changes that underlie human disease and injury.
Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.
Architecture and industry: the migrant contribution to nation-building. This project aims to explore the post-war architectural, rural and industrial landscapes of Australia as shaped by the labour of displaced persons. Migrants after the Second World War were critical to the spatial making of modern Australia. Major federally-funded industries driving post-war nation-building programs depended on the employment of large numbers of war-displaced persons. While the immigrant contribution to natio ....Architecture and industry: the migrant contribution to nation-building. This project aims to explore the post-war architectural, rural and industrial landscapes of Australia as shaped by the labour of displaced persons. Migrants after the Second World War were critical to the spatial making of modern Australia. Major federally-funded industries driving post-war nation-building programs depended on the employment of large numbers of war-displaced persons. While the immigrant contribution to nation-building in cultural terms is well-known, its everyday spatial, architectural and landscape transformations remain unexamined. This project aims to bring to the foreground post-war industry and immigration to comprehensively document a how Australia has uniquely shaped its built environment.Read moreRead less
How do myelinating cells alter brain circuits to facilitate learning? This project aims to identify the brain circuits that receive new insulation and characterise the molecular mediators of this process. This project will apply innovative technologies to understand how the nervous system remains adaptable throughout life. This new knowledge, of the cellular mechanisms that allow brain circuits to remain adaptable throughout life, may have application in the development of interventions aimed at ....How do myelinating cells alter brain circuits to facilitate learning? This project aims to identify the brain circuits that receive new insulation and characterise the molecular mediators of this process. This project will apply innovative technologies to understand how the nervous system remains adaptable throughout life. This new knowledge, of the cellular mechanisms that allow brain circuits to remain adaptable throughout life, may have application in the development of interventions aimed at improving educational outcomes or counteracting age-related memory decline. Potential future benefits include facilitating the development of drugs to circumvent memory loss resulting from brain diseases, and improving the design of neuromorphic hardware for computing.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH220100016
Funder
Australian Research Council
Funding Amount
$2,959,803.00
Summary
ARC Research Hub to Advance Timber for Australia’s Future Built Environment. This project aims to transform Australia’s timber and construction sectors by stimulating rapid growth in timber innovation and uptake of use of timber in buildings. It plans to enable this transformation by addressing the diverse elements required to motivate investment, stimulate innovation, satisfy stakeholder demands, define long-term social-environmental-economic benefits and establish a roadmap for change. The exp ....ARC Research Hub to Advance Timber for Australia’s Future Built Environment. This project aims to transform Australia’s timber and construction sectors by stimulating rapid growth in timber innovation and uptake of use of timber in buildings. It plans to enable this transformation by addressing the diverse elements required to motivate investment, stimulate innovation, satisfy stakeholder demands, define long-term social-environmental-economic benefits and establish a roadmap for change. The expected outcomes will kickstart the change process, supported by growth in advanced manufacturing across the value chain. This should provide significant benefits in stimulating an opportunity for regional development and resource diversification whilst helping the sectors transition to a circular and net-zero economy.Read moreRead less
Architectural Work Cultures: professional identity, education and wellbeing. This project aims to examine the work and study cultures of architecture in Australia, in relation to professional identity, and in terms of impact on wellbeing, with a whole-of-career scope spanning education to retirement. It will generate the first comprehensive account of work-related wellbeing problems for both architectural practitioners and students, via qualitative and quantitative methods and a vigorous engagem ....Architectural Work Cultures: professional identity, education and wellbeing. This project aims to examine the work and study cultures of architecture in Australia, in relation to professional identity, and in terms of impact on wellbeing, with a whole-of-career scope spanning education to retirement. It will generate the first comprehensive account of work-related wellbeing problems for both architectural practitioners and students, via qualitative and quantitative methods and a vigorous engagement with the profession. Expected outcomes include two toolkits to assist the profession to support cultural change across educational, workplace and institutional settings. This should provide significant benefits for the wellbeing of architects at all career stages, and also support the long-term viability of the sector.Read moreRead less
ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environme ....ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environments. EII will address 3 tightly coupled research themes: Ability to interoperate across existing heterogenous platforms & applications; Efficient processing of very large data sets; Technology adoption & impact. Generic results will be applicable to e-science and large business information systems installations.Read moreRead less